Pathogenesis of Rapidly Progressive Glomerulonephritis: What Do We Learn?

2013 ◽  
pp. 207-215 ◽  
Author(s):  
Yong-Xi Chen ◽  
Nan Chen
Keyword(s):  
Rapidly Progressive Glomerulonephritis

Rapidly progressive glomerulonephritis as presenting feature of systemic lupus erythematosus in a Bangladeshi male patient: a rare case report

2020 ◽  
Vol 10 (2) ◽  
pp. 137-138
Author(s):  
Samiha Haque ◽  
Ishrat Jahan ◽  
Tufayel Ahmed Chowdhury ◽  
Muhammad Abdur Rahim ◽  
Mehruba Alam Ananna ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Venous Pressure ◽  
Rapidly Progressive Glomerulonephritis ◽  
Initial Response ◽  
Systemic Lupus ◽  
Renal Manifestation ◽  
Rare Case Report ◽  
Diagnostic Work ◽  
Work Up

Rapidly progressive glomerulonephritis is one of the most dramatic and tragic presentations of lupus nephritis (LN) or renal manifestation of systemic lupus erythematosus (SLE). A 35-year-old Bangladeshi gentleman presented with worsening oedema, scanty, high colored, frothy urine and deteriorating renal function. He had puffy face, anaemia, oedema, normal jugular venous pressure (JVP), high blood pressure (150/90 mm Hg), ascites and bilateral pleural effusions. Diagnostic work-up confirmed SLE with class IV LN. His initial response to specific therapy showed improvement Birdem Med J 2020; 10(2): 137-138

scholarly journals SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Alexander Winkler ◽  
Emanuel Zitt ◽  
Hannelore Sprenger-Mähr ◽  
Afschin Soleiman ◽  
Manfred Cejna ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Plasma Cells ◽  
Rapidly Progressive Glomerulonephritis ◽  
Kidney Injury ◽  
Pulmonary Involvement ◽  
Pulmonary Haemorrhage ◽  
Basement Membranes ◽  
High Avidity ◽  
History Of

Abstract Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage. Recently, an association between COVID-19 and anti-glomerular basement membrane (anti-GBM) disease has been proposed. We report on a patient with recurrence of anti-GBM disease after SARS-CoV-2 infection. Case presentation The 31-year-old woman had a past medical history of anti-GBM disease, first diagnosed 11 years ago, and a first relapse 5 years ago. She was admitted with severe dyspnoea, haemoptysis, pulmonary infiltrates and acute on chronic kidney injury. A SARS-CoV-2 PCR was positive with a high cycle threshold. Anti-GBM autoantibodies were undetectable. A kidney biopsy revealed necrotising crescentic glomerulonephritis with linear deposits of IgG, IgM and C3 along the glomerular basement membrane, confirming a recurrence of anti-GBM disease. She was treated with steroids, plasma exchange and two doses of rituximab. Pulmonary disease resolved, but the patient remained dialysis-dependent. We propose that pulmonary involvement of COVID-19 caused exposure of alveolar basement membranes leading to the production of high avidity autoantibodies by long-lived plasma cells, resulting in severe pulmonary renal syndrome. Conclusion Our case supports the assumption of a possible association between COVID-19 and anti-GBM disease.

A Case of Rapidly Progressive Glomerulonephritis Associated With Bucillamine-Treated Rheumatoid Arthritis

1992 ◽  
Vol 20 (4) ◽  
pp. 411-413 ◽  
Author(s):  
Atsuhiro Yoshida ◽  
Kunio Morozumi ◽  
Asami Takeda ◽  
Katsushi Koyama ◽  
Tadashi Oikawa ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rapidly Progressive Glomerulonephritis

scholarly journals The therapy of rapidly progressive glomerulonephritis

1983 ◽  
Vol 61 (24) ◽  
pp. 1254-1254
Author(s):  
H. G. Sieberth ◽  
N. Maurin
Keyword(s):  
Rapidly Progressive Glomerulonephritis

β1 and β3 integrin upregulation in rapidly progressive glomerulonephritis

1995 ◽  
Vol 10 (7) ◽  
pp. 1155-1161 ◽  
Author(s):  
A. Baraldi ◽  
G. Zambruno ◽  
L. Furci ◽  
M. Ballestri ◽  
A. Tombesi ◽  
...  
Keyword(s):  
Rapidly Progressive Glomerulonephritis ◽  
Β3 Integrin

scholarly journals FMS-Like Tyrosine Kinase 3 Ligand Treatment Does Not Ameliorate Experimental Rapidly Progressive Glomerulonephritis

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0123118
Author(s):  
Joanna R. Ghali ◽  
Kim M. O’Sullivan ◽  
Peter J. Eggenhuizen ◽  
Stephen R. Holdsworth ◽  
A. Richard Kitching
Keyword(s):  
Tyrosine Kinase ◽  
Rapidly Progressive Glomerulonephritis
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