Neuronal Migration Defect of the Developing Cerebellar Vermis in Substrains of C57BL/6 Mice: Cytoarchitecture and Prevalence of Molecular Layer Heterotopia

2013 ◽  
Vol 35 (1) ◽  
pp. 28-39 ◽  
Author(s):  
Zareema Mangaru ◽  
Elsaid Salem ◽  
Matthew Sherman ◽  
Sarah E. Van Dine ◽  
Ankur Bhambri ◽  
...  
Keyword(s):  
Neuronal Migration ◽  
Molecular Layer ◽  
Cerebellar Vermis ◽  
Neuronal Migration Defect

Array-based characterization of an interstitial de-novo deletion of chromosome 4q in a patient with a neuronal migration defect and hypocalcemia plus a literature review

2012 ◽  
Vol 21 (3) ◽  
pp. 172-176 ◽  
Author(s):  
Marta Moreno-García ◽  
Jaime Sánchez del Pozo ◽  
Jaime Cruz-Rojo ◽  
Francisco Javier Fernández-Martínez ◽  
Guiomar Perez-Nanclares Leal
Keyword(s):  
Literature Review ◽  
Neuronal Migration ◽  
De Novo ◽  
Neuronal Migration Defect

Axonal anatomy of molecular layer heterotopia of the cerebellar vermis

2013 ◽  
Vol 47 ◽  
pp. 90-95 ◽  
Author(s):  
Sarah E. Van Dine ◽  
Elsaid Salem ◽  
Dhruv B. Patel ◽  
Elizabeth George ◽  
Raddy L. Ramos
Keyword(s):  
Molecular Layer ◽  
Cerebellar Vermis

Unilateral megalencephaly associated with contralateral neuronal migration defect

1999 ◽  
Vol 43 (3) ◽  
pp. 346-348 ◽  
Author(s):  
Arzu Arslan ◽  
Ali Demırcı ◽  
Ercüment Çıftçı
Keyword(s):  
Neuronal Migration ◽  
Neuronal Migration Defect

scholarly journals Neuronal Migration Defect: A Case of Subcortical Heterotopia in a California Sea Lion

2008 ◽  
Vol 45 (3) ◽  
pp. 412-416 ◽  
Author(s):  
B. Blankenship ◽  
C. Dold ◽  
E. Jensen ◽  
C. Smith ◽  
W. Van Bonn ◽  
...  
Keyword(s):  
Neuronal Migration ◽  
Sea Lion ◽  
California Sea Lion ◽  
Neuronal Migration Defect

scholarly journals Regional distributions of choline acetyltransferase and acetylcholinesterase activities in layers of rat cerebellar vermis.

1983 ◽  
Vol 31 (7) ◽  
pp. 927-937 ◽  
Author(s):  
C D Ross ◽  
J T Smith ◽  
D A Godfrey
Keyword(s):  
Choline Acetyltransferase ◽  
Granular Layer ◽  
Molecular Layer ◽  
Mossy Fibers ◽  
Acetylcholinesterase Activity ◽  
Cerebellar Vermis ◽  
Numerical Density ◽  
Acetyltransferase Activity ◽  
Acetylcholinesterase Staining ◽  
Choline Acetyltransferase Activity

Entire sagittal sections of rat cerebellar vermis were dissected into microgram-sized samples of molecular, granular, and white matter layers. Assayed activities of choline acetyltransferase and acetylcholinesterase were plotted back onto sectional maps of exact sample locations. On the average, the activities of choline acetyltransferase and acetylcholinesterase in the granular layer were about four and five times, respectively, those in the molecular layer. The highest activity of both enzymes was in the granular layer of the vestibulocerebellum, the nodulus and ventral uvula (lobules X and IXc of Larsell). This activity might be related to the secondary vestibulocerebellar projection, terminating as mossy fibers in the granular layer of this region. Intermediate levels of activity were found in the granular layer of the dorsal uvula (lobule IX, a and b). The lowest activities of both enzymes in the granular layer were in the culmen (lobule V). A 7.1-fold difference in choline acetyltransferase activity and a 4.5-fold difference in acetylcholinesterase activity were found between the granular layer of lobules V and X. The numerical density of aggregates of acetylcholinesterase staining product in the granular layer correlated much better with assayed acetylcholinesterase activity than with choline acetyltransferase activity.

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