Effects of a High-Protein Diet on Insulin Resistance and Body Fat in Catch-Up Growth Rats Born Small for Gestational Age

2012 ◽  
Vol 78 (3) ◽  
pp. 180-187 ◽  
Author(s):  
Hong-Zhu Deng ◽  
Hong Deng ◽  
Yan-Hong Li ◽  
Zhe Su ◽  
Hua-Mei Ma ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Body Fat ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Catch Up

scholarly journals Premature small for gestational age infants fed an exclusive human milk-based diet achieve catch-up growth without metabolic consequences at 2 years of age

2018 ◽  
Vol 104 (3) ◽  
pp. F242-F247 ◽  
Author(s):  
Chonnikant Visuthranukul ◽  
Steven A Abrams ◽  
Keli M Hawthorne ◽  
Joseph L Hagan ◽  
Amy B Hair
Keyword(s):  
Insulin Resistance ◽  
Body Composition ◽  
Birth Weight ◽  
Human Milk ◽  
Premature Infants ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Insulin Level ◽  
Metabolic Outcomes ◽  
Catch Up

ObjectiveTo compare postdischarge growth, adiposity and metabolic outcomes of appropriate for gestational age (AGA) versus small for gestational age (SGA) premature infants fed an exclusive human milk (HM)-based diet in the neonatal intensive care unit.DesignPremature infants (birth weight ≤1250 g) fed an exclusive HM-based diet were examined at 12–15 months corrected gestational age (CGA) (visit 1) for anthropometrics, serum glucose and non-fasting insulin, and at 18–22 months CGA (visit 2) for body composition by dual-energy X-ray absorptiometry.ResultsOf 51 children, 33 were AGA and 18 were SGA at birth. The SGA group had weight gain (g/day) equal to AGA group during the follow-up period. SGA had a significantly greater body mass index (BMI) z-score gain from visit 1 to visit 2 (0.25±1.10 vs −0.21±0.84, p=0.02) reflecting catch-up growth. There were no significant differences in total fat mass (FM) and trunk FM between groups. SGA had significantly lower insulin level (5.0±3.7 vs 17.3±15.1 µU/mL, p=0.02) and homeostatic model of assessment-insulin resistance (1.1±0.9 vs 4.3±4.1, p=0.02). Although regional trunk FM correlated with insulin levels in SGA (r=0.893, p=0.04), they had lower insulin level compared with AGA and no difference in adiposity.ConclusionsSGA premature infants who received an exclusive HM-based diet exhibited greater catch-up growth without increased adiposity or elevated insulin resistance compared with AGA at 2 years of age. An exclusive HM-based diet may improve long-term body composition and metabolic outcomes of premature infants with ≤1250 g birth weight, specifically SGA.

554 A High Protein Diet Reduces Body Fat Mass and Alters the Gut Microbiome, With Expansion of Akkermansia, in a Rat Model of Diet-Induced Obesity

2016 ◽  
Vol 150 (4) ◽  
pp. S117
Author(s):  
Jonathan Jacobs ◽  
Lixin Wang ◽  
Mulugeta Million ◽  
Joseph R. Pisegna ◽  
Yvette Tache
Keyword(s):  
Body Fat ◽  
Fat Mass ◽  
Rat Model ◽  
Gut Microbiome ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Body Fat Mass ◽  
Diet Induced Obesity

scholarly journals Protein source in a high-protein diet modulates reductions in insulin resistance and hepatic steatosis in fa/fa Zucker rats

Obesity ◽  
2015 ◽  
Vol 24 (1) ◽  
pp. 123-131 ◽  
Author(s):  
Jennifer L. Wojcik ◽  
Jessay G. Devassy ◽  
Yinghong Wu ◽  
Peter Zahradka ◽  
Carla G. Taylor ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Hepatic Steatosis ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Source ◽  
Protein Diet ◽  
Zucker Rats

scholarly journals A high-protein diet for reducing body fat: mechanisms and possible caveats

2014 ◽  
Vol 11 (1) ◽  
pp. 53 ◽  
Author(s):  
Dominik H Pesta ◽  
Varman T Samuel
Keyword(s):  
Body Fat ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet

Insulin resistance and its association with catch-up growth in Chinese children born small for gestational age

Obesity ◽  
2016 ◽  
Vol 25 (1) ◽  
pp. 172-177 ◽  
Author(s):  
Chunhua Liu ◽  
Baiyan Wu ◽  
Niyang Lin ◽  
Xiaoyi Fang
Keyword(s):  
Insulin Resistance ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Chinese Children ◽  
Catch Up
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