Pharmacological Interventions for Short Stature: Pros and Cons

Author(s):  
Ron G. Rosenfeld
2007 ◽  
Vol 41 (12) ◽  
pp. 29
Author(s):  
KERRI WACHTER
Keyword(s):  

Praxis ◽  
2020 ◽  
Vol 109 (14) ◽  
pp. 1141-1149
Author(s):  
Martina Boscolo Berto ◽  
Dominik C. Benz ◽  
Christoph Gräni

Abstract. Coronary artery disease (CAD) is the leading cause of morbidity and mortality in the industrialized countries. Assessment of symptomatic patients with suspected obstructive CAD is a common reason for a clinical visit. Noninvasive anatomical and functional imaging are established tools to rule-in and rule-out CAD, to assess the severity of disease and to determine the potential risk of future cardiovascular events. In this review, we discuss the updated Guidelines from the European Society of Cardiology on Chronic Coronary Syndromes and explore the different imaging modalities used in current clinical practice for the noninvasive assessment of CAD. The pros and cons of each method, especially comparing anatomical and functional testing, are presented. Furthermore we we address the practical clinical aspects in the selection of the optimal noninvasive tests according to clinical need.


Crisis ◽  
2012 ◽  
Vol 33 (2) ◽  
pp. 106-112 ◽  
Author(s):  
Christopher M. Bloom ◽  
Shareen Holly ◽  
Adam M. P. Miller

Background: Historically, the field of self-injury has distinguished between the behaviors exhibited among individuals with a developmental disability (self-injurious behaviors; SIB) and those present within a normative population (nonsuicidal self-injury; NSSI),which typically result as a response to perceived stress. More recently, however, conclusions about NSSI have been drawn from lines of animal research aimed at examining the neurobiological mechanisms of SIB. Despite some functional similarity between SIB and NSSI, no empirical investigation has provided precedent for the application of SIB-targeted animal research as justification for pharmacological interventions in populations demonstrating NSSI. Aims: The present study examined this question directly, by simulating an animal model of SIB in rodents injected with pemoline and systematically manipulating stress conditions in order to monitor rates of self-injury. Methods: Sham controls and experimental animals injected with pemoline (200 mg/kg) were assigned to either a low stress (discriminated positive reinforcement) or high stress (discriminated avoidance) group and compared on the dependent measures of self-inflicted injury prevalence and severity. Results: The manipulation of stress conditions did not impact the rate of self-injury demonstrated by the rats. The results do not support a model of stress-induced SIB in rodents. Conclusions: Current findings provide evidence for caution in the development of pharmacotherapies of NSSI in human populations based on CNS stimulant models. Theoretical implications are discussed with respect to antecedent factors such as preinjury arousal level and environmental stress.


Author(s):  
Charles A. Peterson

Abstract. Content analysis is a late and contentious addition to the Rorschach canon. The determinants have ruled. Hermann Rorschach was at best, ambivalent about content analysis, focusing on the perceptual aspects of the process. Rorschachers have been not been conTENT about CONtent. The literature on the pros and cons and the how-to of content analysis is reviewed chronologically, concluding with eight issues and objections that have left Rorschach practitioners malcontent with content. Hoping to help practitioners improve the analysis of Rorschach content, ten suggestions, often with examples, are offered, these “hints” affecting both conceptualization and practice. A case fragment is appended to the review to host the above suggestions and to illustrate the (likely) less frequent “active evocation” of content to further the analysis.


PsycCRITIQUES ◽  
2006 ◽  
Vol 51 (10) ◽  
Author(s):  
Robert T. Hitlan ◽  
M. Catherine DeSoto
Keyword(s):  

PsycCRITIQUES ◽  
2006 ◽  
Vol 51 (30) ◽  
Author(s):  
Katerina Bezrukova
Keyword(s):  

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