The Unique Liquid-Based Cytologic Findings of Thyroid Signet-Ring Follicular Adenoma: A Report of Two Cases with Fine Needle Aspiration Cytology

2013 ◽  
Vol 57 (1) ◽  
pp. 100-106 ◽  
Author(s):  
Yoon Yang Jung ◽  
Mi Kyung Kim ◽  
Tae Jin Lee ◽  
Chung Hun Lee ◽  
Chae Young Lee ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Follicular Adenoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Signet Ring ◽  
Needle Aspiration Cytology

scholarly journals Correlation between fine needle aspiration cytology and histopathological examination in thyroid swellings-a pilot study

2020 ◽  
Vol 7 (11) ◽  
pp. 4381
Author(s):  
Sanjay V. Gupta ◽  
Manish Munjal ◽  
Devyani Gupta ◽  
Siddharth Gupta ◽  
Shubham Munjal ◽  
...  
Keyword(s):  
Papillary Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Nodules ◽  
Follicular Adenoma ◽  
Follicular Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Thyroid swellings are an enigma that necessitates either, a partial thyroidectomy and a tissue diagnosis to be followed by completion surgery or straightaway a radical intervention. A preoperative presumptive diagnosis of a thyroid swelling, solitary or otherwise is correlated with the post-surgical histopathological finding in the present study.Methods: 30 patients of thyroid nodules were selected from the head-neck tumour clinic of Dayanand medical college hospital, Ludhiana. Pre-operative fine needle aspiration cytology (FNAC) was performed and subjects taken for thyroidectomy, partial or total as the case maybe.Results: There were 20 (66.6%) females in the age group 25-65 years and 10 males (33.3%) 19-50 years with thyroid nodules. 86.6%, 26 patients were of follicular adenoma, 10% 3 patients of papillary carcinoma and 3.33% 1 patient of follicular carcinoma. No case in this study was reported as medullary carcinoma. In the cytological diagnosis of follicular neoplasm in 5 cases, 3 were diagnosed as thyroid adenoma, 2 were finally found to be papillary carcinoma. Overall sensitivity of fine needle aspiration was 40%. There was 84.6% agreement in follicular adenoma; 33% in papillary carcinoma and 100% in follicular carcinoma, and overall accuracy was 85.7%.Conclusion: FNAC is an ideal preoperative investigative modality in thyroid swellings with overall accuracy of 85 % and can differentiate preoperatively a benign from a   malignant thyromegaly; and thereby plan extent of surgery, with or without a neck dissection, Maximum cases of follicular adenoma could be easily diagnosed with this aspiration modality.                                               

scholarly journals A clinicopathological evaluation of solitary nodule in thyroid; a retrospective observational hospital based study

2020 ◽  
Vol 7 (12) ◽  
pp. 3951
Author(s):  
Y. Ananta Lakshmi ◽  
K. V. Narasimha Reddy
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Benign Lesion ◽  
Follicular Adenoma ◽  
Needle Aspiration ◽  
Neoplastic Disease ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Solitary Nodule ◽  
Needle Aspiration Cytology

Background: The solitary node in thyroid is a palpably discrete swelling within an apparently normal thyroid gland. It is usually a benign lesion but from clinical standpoint the possibility of neoplastic disease is of major concern for surgeon and patient. AS there is variability in the conclusion of various authors and there is no work about clinicopathology of solitary nodules of thyroid in our region. Present study has been designed to evaluate the epidemiology, fine needle aspiration cytology and incidence of malignancy in solitary nodule.Methods: As per exclusion and inclusion criteria 80 patients with solitary nodule of thyroid were included in this study. Various data like age, sex, family history, duration of nodule, site and size of nodule were recorded. Thyroid function test, fine needle aspiration cytology and ultrasonographic finding were recorded from case record.Results: Out of all histopathological finding of nodules follicular adenoma was most common followed by multinodular goitre (25%) and Adenomatous goitre (7.5%). Carcinoma was present in (17.5 %) and thyroiditis is 7.5% patients.Conclusions: Most of the patients were Euthyroid and benign condition was more common than malignancy. Follicular adenoma was most common among benign lesion and papillary carcinoma was more common neoplasm. Most of the patients required hemithyroidectomy.

scholarly journals Comparative study of FNAC and histopathology in the diagnosis of thyroid swelling

1970 ◽  
Vol 16 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Md Shafiqul Islam ◽  
Belayat Hossain Siddiquee ◽  
Nasima Akhtar ◽  
Kazi Shameemus Salam ◽  
Mohammad Aktaruzzaman
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Follicular Adenoma ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Histopathological Analysis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

The objective of this study was to determine the efficacy of fine needle aspiration cytology indiagnosis and management of thyroid swelling. The study evaluated the predictive value ofPre operative fine needle aspiration cytology (FNAC) in surgical decision making, by comparingthis (FNAC) with the post operative histopathological diagnosis.Ninety patients who underwent thyroidectomy between Jan-2007 to Dec-2008 were analysedin the department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh MujibMedical University, Dhaka. All the patients underwent pre operative FNAC were included inthis study.FNAC was accurate in 85 (94.44%) patients. Failure were mainly noted in cases of follicularneoplasm (lesion). Our result indicates that FNAC is helpful in the diagnosis and surgicalplanning of thyroid swelling. However, histopathological analysis is still remaining essential todistinguish follicular adenoma from follicular carcinoma.Key words: FNAC; Histopathology; Thyroid swellingDOI: 10.3329/bjo.v16i1.5779Bangladesh J Otorhinolaryngol 2010; 16(1): 35-43

Role of fine needle aspiration cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm

2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Preoperative Diagnostic ◽  
Needle Aspiration Cytology

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118

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