Ventricular Strain in Fetuses with Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome before and after Prenatal Aortic Valvuloplasty

2013 ◽  
Vol 35 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Tetsuko Ishii ◽  
Doff B. McElhinney ◽  
David M. Harrild ◽  
Edward N. Marcus ◽  
David J. Sahn ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Hypoplastic Left Heart Syndrome ◽  
Left Heart ◽  
Hypoplastic Left Heart ◽  
Aortic Valvuloplasty ◽  
Before And After ◽  
Left Heart Syndrome

Foetal aortic valvuloplasty: experience of five cases

2013 ◽  
Vol 23 (5) ◽  
pp. 675-681 ◽  
Author(s):  
Pablo Marantz ◽  
Horacio Aiello ◽  
Sofía Grinenco ◽  
Gustavo Izbizky ◽  
Gabriela Peña ◽  
...  
Keyword(s):  
At Risk ◽  
Aortic Stenosis ◽  
Hypoplastic Left Heart Syndrome ◽  
Severe Aortic Stenosis ◽  
Clinical Aspects ◽  
Left Heart ◽  
Hypoplastic Left Heart ◽  
Aortic Valvuloplasty ◽  
Risk Of Progression ◽  
Left Heart Syndrome

AbstractObjectivesFoetal aortic valvuloplasty has been proposed as a strategy to improve left heart growth and function in foetuses with severe aortic stenosis at risk of progression to hypoplastic left heart syndrome. We report our experience with this intervention.Methods and resultsBetween 2005 and 2010, five foetuses with aortic stenosis and at risk of progression to hypoplastic left heart syndrome underwent ultrasound-guided percutaneous foetal aortic valvuloplasty. There were no associated maternal complications or foetal demise. In one case, the pregnancy was terminated a couple of weeks after the intervention, one foetus evolved to hypoplastic left heart syndrome, and three did not.ConclusionsFoetal aortic valvuloplasty seems to be a safe and feasible procedure. It has been reported that it has the potential to prevent progression to hypoplastic left heart syndrome in selected foetuses with severe aortic stenosis. Further investigation regarding physiological and clinical aspects of this disease both prenatally and postnatally will probably allow to improve therapeutic strategies and clinical outcome.

scholarly journals OC181: In utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome

2008 ◽  
Vol 32 (3) ◽  
pp. 302-302
Author(s):  
D. B. McElhinney ◽  
A. C. Marshall ◽  
L. E. Wilkins-Haug ◽  
C. B. Benson ◽  
V. Silva ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Hypoplastic Left Heart Syndrome ◽  
In Utero ◽  
Left Heart ◽  
Hypoplastic Left Heart ◽  
Aortic Valvuloplasty ◽  
Left Heart Syndrome

Assessment of Left Ventricular Endocardial Fibroelastosis in Fetuses With Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome

2010 ◽  
Vol 106 (12) ◽  
pp. 1792-1797 ◽  
Author(s):  
Doff B. McElhinney ◽  
Melanie Vogel ◽  
Carol B. Benson ◽  
Audrey C. Marshall ◽  
Louise E. Wilkins-Haug ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Hypoplastic Left Heart Syndrome ◽  
Left Ventricular ◽  
Left Heart ◽  
Endocardial Fibroelastosis ◽  
Hypoplastic Left Heart ◽  
Left Heart Syndrome
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