scholarly journals Validity of Laparoscopic Staging to Avoid Adjuvant Chemoradiation following Radical Surgery in Patients with Early Cervical Cancer

Oncology ◽  
2012 ◽  
Vol 83 (6) ◽  
pp. 346-353 ◽  
Author(s):  
Simone Marnitz ◽  
Christhardt Köhler ◽  
Renato Jose Affonso ◽  
Achim Schneider ◽  
Vito Chiantera ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Radical Surgery ◽  
Laparoscopic Staging ◽  
Adjuvant Chemoradiation ◽  
Early Cervical Cancer

Weekly Cisplatin Therapy Compared With Triweekly Combination Chemotherapy as Concurrent Adjuvant Chemoradiation Therapy After Radical Hysterectomy for Cervical Cancer

2011 ◽  
Vol 21 (1) ◽  
pp. 128-136 ◽  
Author(s):  
Hae Nam Lee ◽  
Keun Ho Lee ◽  
Dae Woo Lee ◽  
Yong Seok Lee ◽  
Eun Kyung Park ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Overall Survival ◽  
Combination Chemotherapy ◽  
Radical Hysterectomy ◽  
Radical Surgery ◽  
Disease Free Survival ◽  
Chemoradiation Therapy ◽  
Adjuvant Chemoradiation ◽  
Chemotherapy Group ◽  
Weekly Cisplatin

Objective:To evaluate whether the use of triweekly combination chemotherapy together with radiation exerts a more beneficial systemic effect than weekly cisplatin chemoradiation in patients with cervical cancer after radical surgery.Methods:We retrospectively analyzed patients with stage IB1 to stage IIB cervical cancer who had undergone radical hysterectomy with pelvic lymph node dissection, followed by concurrent adjuvant chemoradiation therapy. The patients were divided into 2 groups: the triweekly combination chemotherapy group and the weekly cisplatin chemotherapy group. We evaluated the survival and adverse effects of the 2 groups.Results:In total, 201 patients were included. The mean duration of follow-up was 52.2 months. Of the 201 patients, 130 received triweekly combination chemotherapy, and 71 patients received weekly cisplatin chemotherapy as an adjuvant treatment. The 5-year disease-free survival was 82.2% for patients treated with weekly cisplatin chemotherapy and 74.3% for those treated with triweekly combination chemotherapy (P= 0.3929). The 5-year overall survival was 81.4% and 79.3% for the same treatment groups, respectively (P= 0.9833). The overall survival of the patients with stage IIB cervical cancer was marginally higher in the triweekly combination chemotherapy group than in the weekly cisplatin group (P= 0.0582). Leukopenia, neutropenia, thrombocytopenia, anemia, and hepatopathy were significantly more common in the triweekly combination chemotherapy group.Conclusions:The weekly cisplatin chemotherapy group experienced the same therapeutic effect as the triweekly combination chemotherapy group but with less toxicity. Therefore, weekly cisplatin chemotherapy is considered the more useful concurrent adjuvant chemoradiation regimen after radical surgery.

Fertility-Sparing Surgery for Early Cervical Cancer—Approach to Less Radical Surgery

2012 ◽  
Vol 22 (2) ◽  
pp. 311-317 ◽  
Author(s):  
Shanti Kankipati Raju ◽  
Andreas John Papadopoulos ◽  
Stephen Attard Montalto ◽  
Michael Coutts ◽  
Giuseppe Culora ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Radical Surgery ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing ◽  
Early Cervical Cancer

Transrectal ultrasound (TRUS) and MRI in staging of early cervical cancer

2007 ◽  
Vol 28 (S 1) ◽  
Author(s):  
D Fischerova ◽  
D Cibula ◽  
M Zikan ◽  
P Calda ◽  
H Vondrichova ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Transrectal Ultrasound ◽  
Early Cervical Cancer

Efficiency of diagnosis and treatment non-invasive and microinvasive sgamous cell cervical cancer

2020 ◽  
pp. 71-74
Author(s):  
M.M. Melnyk ◽  
◽  
S.V. Nespradko ◽  
I.V. Goncharuk ◽  
M.V. Marchenko ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Key Words ◽  
National Cancer Institute ◽  
Reproductive Function ◽  
Diagnosis And Treatment ◽  
Non Invasive ◽  
Corpus Uteri ◽  
Complex Program ◽  
Early Cervical Cancer

The objective: analyse the effectiveness of diagnosis and treatment for early cervical cancer. Materials and methods. Analysed 107 cases of women’s disease on CIN ІІІ, cancer in situ, they were on treatment in National cancer institute and Kyiv dictrict cancer dispensary from 2010 till 2015 years. Results. Diagnosed percent relapse CIN ІІІ, cancer in situ contain 4.57% uninvasive and invasive form – 0.94%. Conclusion. According diagnostic CIN ІІ and CIN ІІІ is recommended to do treatment conization and dynamic dispensary observation. Are making complex program of infection HPV16, 18. In appering of margins resection some elements of tumor after wider conization by forms of cancer in situ. Many of expansive burns in cervical glands, in making of reproductive function, going disease (nodel leiomyoma of corpus uteri etc). In perspective is accept the notion of looking after and screening research of considering infection HPV16, 18 on CIN І, CIN ІІ. Key words: cervical cancer, сancer in situ, CIN І–ІІІ, diagnostic, treatment, conization.

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