scholarly journals Elevated Interleukin-6 Concentration and Alterations of the Coagulation System Are Associated with the Development of Intraventricular Hemorrhage in Extremely Preterm Infants

Neonatology ◽  
2012 ◽  
Vol 102 (4) ◽  
pp. 270-275 ◽  
Author(s):  
Christine Poralla ◽  
Hans-Jörg Hertfelder ◽  
Johannes Oldenburg ◽  
Andreas Müller ◽  
Peter Bartmann ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Interleukin 6 ◽  
Intraventricular Hemorrhage ◽  
Coagulation System ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

scholarly journals The coagulation system of extremely preterm infants: influence of perinatal risk factors on coagulation

2011 ◽  
Vol 32 (11) ◽  
pp. 869-873 ◽  
Author(s):  
C Poralla ◽  
C Traut ◽  
H-J Hertfelder ◽  
J Oldenburg ◽  
P Bartmann ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Infants ◽  
Coagulation System ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

scholarly journals Early pulmonary hypertension is a risk factor for bronchopulmonary dysplasia-associated late pulmonary hypertension in extremely preterm infants

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hyun Ho Kim ◽  
Se In Sung ◽  
Mi Sun Yang ◽  
Yea Seul Han ◽  
Hye Seon Kim ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Risk Factor ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Odds Ratio ◽  
Intraventricular Hemorrhage ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Grade 3 ◽  
Ventilator Care

AbstractThis study evaluated whether early pulmonary hypertension (PH) in extremely preterm infants (EPIs) at 22–27 weeks of gestation detected clinically with echocardiography at 4–7 postnatal days (PND) is a risk factor for death before 36 weeks post-menstrual age (PMA) or late PH in moderate or severe (m/s) bronchopulmonary dysplasia (BPD) (BPD-PH). We analyzed risk factors for death before 36 weeks PMA or BPD-PH. Among 247 EPIs enrolled, 74 (30.0%) had early PH. Twenty-one (28.4%) infants with early PH and 18 (10.4%) without early PH died before 36 weeks PMA; 14 (18.9%) infants with early PH and 9 (5.2%) without early PH had BPD-PH at 36–38 weeks PMA. Multivariate analysis revealed that early PH (adjusted odds ratio, 6.55; 95% confidence interval, 3.10–13.82, P < 0.05), clinical chorioamnionitis (2.50; 1.18–5.31), intraventricular hemorrhage (grade 3–4) (3.43; 1.26–9.37), and late sepsis (6.76; 3.20–14.28) independently increased the risk of development of death before 36 weeks PMA or BPD-PH. Subgroup analysis among m/s BPD patients revealed that early PH (4.50; 1.61–12.58) and prolonged invasive ventilator care (> 28 days) (4.91; 1.02–23.68) increased the risk for late PH independently. In conclusion, EPIs with early PH at 4–7 PND should be monitored for BPD-associated late PH development.

Global incidence of intraventricular hemorrhage among extremely preterm infants: a systematic literature review

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Csaba Siffel ◽  
Kristin D. Kistler ◽  
Sujata P. Sarda
Keyword(s):  
North America ◽  
Literature Review ◽  
Preterm Infants ◽  
Systematic Literature Review ◽  
Gestational Age ◽  
Intraventricular Hemorrhage ◽  
Population Based ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Grade 3

Abstract Objectives To conduct a systematic literature review to evaluate the global incidence of intraventricular hemorrhage grade 2–4 among extremely preterm infants. Methods We performed searches in MEDLINE and Embase for intraventricular hemorrhage and prematurity cited in English language observational studies published from May 2006 to October 2017. Included studies analyzed data from infants born at ≤28 weeks’ gestational age and reported on intraventricular hemorrhage epidemiology. Results Ninety-eight eligible studies encompassed 39 articles from Europe, 31 from North America, 25 from Asia, five from Oceania, and none from Africa or South America; both Europe and North America were included in two publications. The reported global incidence range of intraventricular hemorrhage grade 3–4 was 5–52% (Europe: 5–52%; North America: 8–22%; Asia: 5–36%; Oceania: 8–13%). When only population-based studies were included, the incidence range of intraventricular hemorrhage grade 3–4 was 6–22%. The incidence range of intraventricular hemorrhage grade 2 was infrequently documented and ranged from 5–19% (including population-based studies). The incidence of intraventricular hemorrhage was generally inversely related to gestational age. Conclusions Intraventricular hemorrhage is a frequent complication of extremely preterm birth. Intraventricular hemorrhage incidence range varies by region, and the global incidence of intraventricular hemorrhage grade 2 is not well documented.

scholarly journals Intraventricular Hemorrhage and Developmental Outcomes at 24 Months of Age in Extremely Preterm Infants

2012 ◽  
Vol 27 (1) ◽  
pp. 22-29 ◽  
Author(s):  
T. Michael O’Shea ◽  
Elizabeth N. Allred ◽  
Karl C. K. Kuban ◽  
Deborah Hirtz ◽  
Barbara Specter ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Intraventricular Hemorrhage ◽  
Developmental Outcomes ◽  
Extremely Preterm ◽  
Extremely Preterm Infants
Sign in / Sign up

Export Citation Format

Share Document