scholarly journals Gastric Mixed Adenoneuroendocrine Carcinoma with a Trilineage Cell Differentiation: Case Report and Review of the Literature

2012 ◽  
Vol 5 (2) ◽  
pp. 313-319 ◽  
Author(s):  
Marinos Pericleous ◽  
Christos Toumpanakis ◽  
Heather Lumgair ◽  
Martyn E. Caplin ◽  
Luke Morgan-Rowe ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Differentiation ◽  
Review Of The Literature ◽  
Mixed Adenoneuroendocrine Carcinoma

scholarly journals Mixed adenoneuroendocrine tumour with squamous differentiation: a case report

2021 ◽  
Vol 11 (1) ◽  
pp. 1891-1894
Author(s):  
Irene Thomas ◽  
Divya Surendran ◽  
Joy Augustine
Keyword(s):  
Case Report ◽  
Cell Differentiation ◽  
Squamous Cell ◽  
Tumour Type ◽  
Squamous Differentiation ◽  
Biological Behaviour ◽  
Rare Tumour ◽  
Mixed Adenoneuroendocrine Carcinoma ◽  
Rare Neoplasm ◽  
Histopathological Features

Mixed adenoneuroendocrine carcinoma is a rare neoplasm with both epithelial and neuroendocrine components. To date, only a few cases of this neoplasm have been reported in the literature among which gastric mixed adenoneuroendocrine carcinoma is very rare. We are reporting a case of gastric mixed adenoneuroendocrine carcinoma with squamous cell differentiation. Histopathological features, biological behaviour and the treatment of this rare tumour type have been discussed briefly.

scholarly journals Cutaneous epithelioid hemangiosarcoma with granular cell differentiation in a dog: a case report and review of the literature

2018 ◽  
Vol 30 (6) ◽  
pp. 951-954 ◽  
Author(s):  
Pompei Bolfa ◽  
Lusan DellaGrotte ◽  
Teri Weronko ◽  
Anibal G. Armien
Keyword(s):  
Case Report ◽  
Cell Differentiation ◽  
Membrane Vesicles ◽  
Granular Cell ◽  
Accurate Diagnosis ◽  
Ultrastructural Changes ◽  
Review Of The Literature ◽  
Neoplastic Cells ◽  
Single Entity ◽  
Immunohistochemical Markers

We report a case of cutaneous epithelioid hemangiosarcoma in a dog in which the majority of the neoplastic cells displayed histologic and ultrastructural features similar to those seen in granular cell tumors (GCTs). This intersection of hemangiosarcoma and granular cell change adds to the argument that GCTs are heterogeneous in histologic origin and underlines the fact that pathologists should not consider all GCTs as a single entity. The combination of histology in typical areas of the tumor with ultrastructural changes and the correct immunohistochemical markers can facilitate the accurate diagnosis of tumors with granular cell differentiation. Besides characteristic intracytoplasmic PAS-positive granules and ultrastructural proteinaceous accumulation within single membrane vesicles (presumably lysosomes and phagolysosomes), we suggest the following combination of markers for the diagnosis of granular cell angiosarcoma and/or hemangiosarcoma: vimentin positive, NSE and/or S100 negative, CD31 positive. We propose that the histologic granular appearance represents a metabolic defect of the neoplastic cells, which supports variability in cell origin for granular cell differentiation.

scholarly journals Primary mucinous carcinoma of thyroid gland with prominent signet-ring-cell differentiation: a case report and review of the literature

2018 ◽  
Vol Volume 11 ◽  
pp. 1521-1528
Author(s):  
Jian Wang ◽  
Qie-Re Guli ◽  
Xiao-Cui Ming ◽  
Hai-Tao Zhou ◽  
Yong-Jie Cui ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Differentiation ◽  
Thyroid Gland ◽  
Mucinous Carcinoma ◽  
Signet Ring Cell ◽  
Review Of The Literature ◽  
Signet Ring ◽  
Ring Cell

scholarly journals Mixed adenoneuroendocrine carcinoma of the esophagus: A case report and review of the literature

2018 ◽  
Vol 24 (2) ◽  
pp. 131 ◽  
Author(s):  
Fernando Mendoza-Moreno ◽  
MR Díez-Gago ◽  
J Mínguez-García ◽  
B Tallón-Iglesias ◽  
G Zarzosa-Hernández ◽  
...  
Keyword(s):  
Case Report ◽  
Review Of The Literature ◽  
Carcinoma Of The Esophagus ◽  
Mixed Adenoneuroendocrine Carcinoma

Anaplastic astrocytoma with granular cell differentiation: Case report and review of the literature

1993 ◽  
Vol 24 (7) ◽  
pp. 805-808 ◽  
Author(s):  
Mark J. Melaragno ◽  
Richard A. Prayson ◽  
Michael A. Murphy ◽  
Samuel J. Hassenbusch ◽  
Melinda L. Estes
Keyword(s):  
Case Report ◽  
Cell Differentiation ◽  
Anaplastic Astrocytoma ◽  
Granular Cell ◽  
Review Of The Literature

scholarly journals Intrahepatic bile duct mixed adenoneuroendocrine carcinoma: a case report and review of the literature

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Sean L. Zheng ◽  
Vincent S. Yip ◽  
Federica Pedica ◽  
Andreas Prachalias ◽  
Alberto Quaglia
Keyword(s):  
Case Report ◽  
Bile Duct ◽  
Intrahepatic Bile Duct ◽  
Review Of The Literature ◽  
Mixed Adenoneuroendocrine Carcinoma

scholarly journals Mixed adenoneuroendocrine carcinoma of the gastric stump following Billroth II gastrectomy: case report and review of the literature

2015 ◽  
Vol 134 (1) ◽  
pp. 84-87 ◽  
Author(s):  
Everton Cazzo ◽  
Helena Paes de Almeida de Saito
Keyword(s):  
Case Report ◽  
Gastric Resection ◽  
Residual Disease ◽  
Review Of The Literature ◽  
Gastric Stump ◽  
Billroth Ii ◽  
Rare Type ◽  
Mixed Adenoneuroendocrine Carcinoma ◽  
Billroth Ii Gastrectomy ◽  
One Year

CONTEXT: Gastric stump cancer after gastric resection is a well-known disease. It may be a newly developed cancer after resection due to benign disease, or recurrent or residual disease after oncological surgery. The predominant histological type is usually adenocarcinoma. This study aimed to report on a rare occurrence of a mixed adenoneuroendocrine carcinoma (MANEC) on the gastric stump. CASE REPORT: The case of an 83-year-old female who presented a locally aggressive gastric stump MANEC, 35 years after Billroth II gastrectomy to treat a peptic ulcer, is reported. The patient underwent resection and adjuvant therapy. She has been followed up for one year without signs of recurrence. CONCLUSION: MANEC is a rare type of gastrointestinal neoplasm. The classification, histopathology, clinical features, treatment issues and prognosis are discussed along with a brief review of the literature.

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