Pitfalls in the Management of Severe Hyponatraemia

Nephron ◽  
2012 ◽  
Vol 120 (4) ◽  
pp. c223-c227 ◽  
Author(s):  
Clare MacEwen ◽  
Peter Watkinson
Keyword(s):  
Severe Hyponatraemia

Active management of severe hyponatraemia by endocrinologists is associated with lower mortality

2018 ◽  
Author(s):  
Aoife Garrahy ◽  
Anne Marie Hannon ◽  
Martin Cuesta ◽  
Bryan Murphy ◽  
William Tormey ◽  
...  
Keyword(s):  
Active Management ◽  
Lower Mortality ◽  
Severe Hyponatraemia

scholarly journals Dialysis for severe hyponatraemia in preeclampsia

2010 ◽  
Vol 3 (2) ◽  
pp. 87-87
Author(s):  
M Bhardwaj ◽  
Archana Dixit
Keyword(s):  
Severe Hyponatraemia

scholarly journals Severe hyponatraemia associated with pre-eclampsia: Table 1

2016 ◽  
pp. bcr2016215036 ◽  
Author(s):  
Breffini Anglim ◽  
Kirk Levins ◽  
Neidin Bussmann ◽  
Mendinaro Imcha
Keyword(s):  
Severe Hyponatraemia

scholarly journals Reduced risk for hospitalization due to hyponatraemia in lithium treated patients: A Swedish population-based case–control study

2020 ◽  
pp. 026988112093759 ◽  
Author(s):  
Henrik Falhammar ◽  
Jakob Skov ◽  
Jan Calissendorff ◽  
Jonatan D Lindh ◽  
Buster Mannheimer
Keyword(s):  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Lithium Therapy ◽  
Inverse Association ◽  
Swedish Population ◽  
Unadjusted Odds Ratio ◽  
Severe Hyponatraemia ◽  
General Swedish Population ◽  
Control Study

Background: Many drugs used in psychiatry have been reported to cause hyponatraemia. However, lithium may be an exception due to its potential for causing nephrogenic diabetes insipidus, but clinical data are largely absent. The objective of this investigation was to study the association between lithium therapy and hospitalization due to hyponatraemia. Methods: This study was a register-based case–control investigation of the general Swedish population. Patients hospitalized with a principal diagnosis of hyponatraemia ( n=11,213) were compared with matched controls ( n=44,801). Analyses using multivariable logistic regression adjusting for co-medication, diseases, previous hospitalizations and socioeconomic factors were deployed to calculate the association between severe hyponatraemia and the use of lithium. Additionally, newly initiated (⩽90 days) and ongoing lithium therapy was studied separately. Results: Compared with controls, the unadjusted odds ratio (OR) (95% confidence interval (CI)) for hospitalization due to hyponatraemia was 1.07 (0.70–1.59) for lithium. However, after adjustment for confounding factors the risk was reduced (adjusted OR: 0.53 (0.31–0.87)). Newly initiated lithium therapy was not significantly associated with hyponatraemia (adjusted OR 0.73 (0.35–5.38)). In contrast, for ongoing therapy the corresponding adjusted OR was significantly reduced (adjusted OR: 0.52 (0.30–0.87)). Conclusions: A marked inverse association was found between ongoing lithium therapy and hospitalization due to hyponatraemia.

scholarly journals Clinical Presentation and Biochemical Abnormalities in Patients Presented with Diabetic Ketoacidosis in BIRDEM Hospital

2017 ◽  
Vol 5 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Suraiya Nazneen ◽  
Fatema Ahmed ◽  
SM Ashrafuzzaman ◽  
Khwaja Nazim Uddin ◽  
ASM Areef Ahsan ◽  
...  
Keyword(s):  
Diabetic Ketoacidosis ◽  
Clinical Presentation ◽  
Insulin Dose ◽  
Respiratory Pattern ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Severe Hyponatraemia ◽  
Age Range ◽  
Time Of Admission ◽  
Biochemical Abnormalities

Objective: To see the clinical presentation and biochemical abnormalities in hospitalized patients of Diabetic ketoacidosis.Methodology: This cross sectional observational study was carried enrolling 55 subjects with Diabetic ketoacidosis, in the Department of Medicine, BIRDEM General Hospital, Dhaka, over a period of six months starting from April 2013 to September 2013.Results: The mean age was 48.35±16.76 with age range from 30 to 68 years. Infection (pneumonia, urinary tract infection, cellulitis) 22(40%), omission of insulin or drugs 14 (25.4%), myocardial infarction 5(9.0%), and reduction of insulin dose 3(5.4%) worked as precipitating cause.Most patients had drowsiness 16(29.0%), moderate dehydration 30(55.5%), signs of infection 22(40%). About 13(23.56%) had Kussmaul’s type of respiratory pattern. Other signs were less obvious. Majority of the subjects 40(72.7%) had 3+ ketonuria at the time of admission in hospital. About 32(58.1%) of the known diabetic patients were on insulin from the beginning of their diagnosis.19 (34.4%) were initially on OHA followed by insulin and 14 (25.4%) patients took OHA alone.7 patients were on dietary modification and exercise without any drugs. Majority 52 (96.46%) patients had blood sugar level between 21-34 mmol/l and mean HbA1c was 12.31(SD±2.50).About 4(7.2%) patients had severe hyponatraemia and 22(40%) patients had hypokalaemia. Eight (14.5%) patients had severe acidosis while 18(32.7%) patients had only mild acidosis. Most of the subjects 29(52.7%) had moderate acidosis. Complete cure from DKA was observed in 53(96.3%) subjects. Only 2(3.6%) subjects developed cerebral oedema. It took 4 to 5 days in mild group, 6 to 8 days in moderate DKA and more than 9 days in severe DKA for recovery.Conclusion: From the study result it could be concluded that infection control and regular administration of insulin or control of diabetes and proper Diabetes Self Management Education (DSME) can prevent diabetic ketoacidosis.Bangladesh Crit Care J March 2017; 5(1): 7-10

A Case of Severe Hyponatraemia

2015 ◽  
pp. 201-207
Author(s):  
Deepa Narayanan ◽  
Julian H. Barth
Keyword(s):  
Severe Hyponatraemia

Severe hyponatraemia after DDAVP stimulation test in an adult patient

Haemophilia ◽  
2008 ◽  
Vol 14 (4) ◽  
pp. 844-845 ◽  
Author(s):  
D. POSTHOUWER ◽  
J. H. ROMMES ◽  
T. J. VAN BEMMEL ◽  
C. G. SCHAAR
Keyword(s):  
Adult Patient ◽  
Stimulation Test ◽  
Severe Hyponatraemia
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