Heart Rate Variability in Peritoneal Dialysis Patients: What Is the Role of Residual Renal Function

2012 ◽  
Vol 34 (1) ◽  
pp. 58-66 ◽  
Author(s):  
Wen Tang ◽  
Li-Xian Li ◽  
Juan Pei ◽  
Tao Wang
2005 ◽  
Vol 23 (6) ◽  
pp. 459-465 ◽  
Author(s):  
Xin-kui Tian ◽  
Yi-sheng Shan ◽  
Xing-wei Zhe ◽  
Li-tao Cheng ◽  
Tao Wang

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Natalia Stepanova ◽  
Lesya Korol ◽  
Lyudmyla Snisar ◽  
Larysa Lebid

Abstract Background and Aims Under physiological conditions, the bulk of circulating oxalate (90% to 95%) is ultimately excreted by the kidneys. Under uremic and/or anuric conditions, dialysis is considered to be the main method of oxalate removal. Nevertheless, little evidence is available on oxalate balance in peritoneal dialysis (PD) patients. The present study aimed to evaluate the separate contribution of residual renal and peritoneal oxalate clearances to oxalate balance in PD patients. Method We performed a cross-sectional observational study involving 62 PD patients with the average age of 50.5±13.5 years and PD vintage of 37±24 months. Plasma oxalate (POx) concentration, levels of daily urinary (UOx) and peritoneal dialysis effluent oxalate (PDEOx) excretion were evaluated. POx concentration was measured spectrophotometrically using MAK315 kit (Sigma, Spain); UOx and PDEOx concentrations were determined using an oxalate oxidase/peroxidase reagent (BioSystems, Spain). In addition, oxalate transport status (4-hour D/P oxalate ratio), renal oxalate clearance (ROxCL) and peritoneal oxalate clearance (PerOxCL) were calculated. Results Among the examined PD patients were 41 (66%) patients with preserved diuresis and 21 (34%) patients with anuria. The anuric PD patients had lower PerOxCL and, accordingly, peritoneal and overall oxalate removal levels compared with the patients with preserved diuresis (Table 1). Conclusion The results of our research demonstrated an important role of the residual renal function in oxalate balance in PD patients. However, the decline in RRF could partially (but not completely) contribute to the increase in POx in PD patients. Thus, PerOxCL but not ROxCL could significantly affect oxalate balance in PD patients.


2011 ◽  
pp. 30-34
Author(s):  
Hoang Bui Bao Hoang ◽  
Huu Loi Le ◽  
Tam Vo ◽  
Thi Anh Thu Tran

Background: Peritoneal dialysis is used regularlly in treatment of ESRDs. Residual renal function (RRF) in these patients helps the adequacy of PD therapy very much. Objectives: 1. Study RRF of PD patients at Department of Nephro – Rheumatology, Hue Central Hospital. 2. Search the correlation between RRF and Kt/V. Patients and methods: 35 PD patients at Department of Nephro – Rheumatology, Hue Central Hospital. Measure RRF and Kt/V by formulars that depend on blood, urine and PD fluid samples. Results: Mean RRF of PD patients is 4.36 ± 13.8 ml/minute. There is a close correlation between RRF and Kt/V (r=0.79, p<0.01). Conclusion: RRF in PD patients correlates with Kt/V.


2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii264-iii264
Author(s):  
Seung Hyeok Han ◽  
Tae Ik Chang ◽  
Dong-Ryeol Ryu ◽  
Tae-Hyun Yoo ◽  
Hyung Jong Kim ◽  
...  

2002 ◽  
Vol 22 (3) ◽  
pp. 415-417 ◽  
Author(s):  
Francisco Caravaca ◽  
Carmen Dominguez ◽  
Manuel Arrobas

2001 ◽  
Vol 21 (3_suppl) ◽  
pp. 152-156 ◽  
Author(s):  
Abelardo Aguilera ◽  
Rosa Codoceo ◽  
M. Auxiliadora Bajo ◽  
Juan J. Diéz ◽  
Gloria Del Peso ◽  
...  

♦ Objective Helicobacter pylori (HP) infection has frequently been found in dialysis patients. Chronic infections induce overproduction of pro-inflammatory substances. Inflammation has been associated with cachexia and anorexia. We explored the relationship between HP infection, anorexia, and malnutrition in peritoneal dialysis (PD) patients. ♦ Patients and Methods The study included 48 clinically stable PD patients divided into four groups: HP+ with anorexia (group I, n = 12); HP+ without anorexia (group II, n = 4); HP- with anorexia (group III, n = 5); and HP- without anorexia (group IV, n = 27). Infection with HP was diagnosed by breath test. Anorexia was evaluated using a personal interview and an eating motivation scale (VAS). The VAS included five questions that are answered before and after eating. The questions concern desire to eat, hunger, feeling of fullness, prospective consumption, and palatability. Biochemical markers of nutrition and inflammation were also determined. ♦ Results At baseline, group I showed lower scores for desire to eat, hunger sensation, prospective consumption, and palatability. They also showed lower lymphocyte counts, prealbumin, transferrin, serum albumin, normalized equivalent of protein–nitrogen appearance (nPNA), and residual renal function (RRF). In addition, the same group showed higher levels of C-reactive protein (CRP) and more sensation of fullness than the remaining groups. In the entire series, we found significant linear correlations between the following markers of nutrition and certain questions on the VAS: albumin with before-lunch desire to eat ( r = 0.38, p < 0.05), and prealbumin with before-lunch hunger ( r = 0.41, p < 0.05) and after-lunch hunger ( r = -0.35, p < 0.05). Negative linear correlations were found between albumin and fullness before lunch ( r = -0.45, p < 0.01), and between prealbumin and before-lunch desire to eat ( r = -0.39, p < 0.05). Negative linear correlations were also seen between CRP and albumin ( r = -0.35, p < 0.05) and between CRP and prealbumin ( r = -0.36, p < 0.05). Similarly, CRP showed a negative correlation with before-lunch desire to eat ( r = -0.38, p < 0.05) and after-lunch desire to eat ( r = -0.45, p < 0.01). After HP eradication, group I showed a significant increase in markers of nutrition and in VAS scores for almost all questions. Simultaneously, they showed a decrease in CRP level. Significant differences were also found in lymphocyte count (1105 ± 259.4 cells/mm3 vs 1330.8 ± 316 cells/mm3, p < 0.05), nPNA (0.9 ± 0.16 g/kg/day vs 1.07 ± 0.3 g/kg/day, p < 0.05), prealbumin (26.7 ± 6.5 mg/dL vs 33.9 ± 56.6 mg/dL, p < 0.01), albumin (3.48 ± 0.3 g/dL vs 3.67 ± 0.35 g/dL, p < 0.05), CRP (1.16 ± 1.14 mg/dL vs 0.88 ± 1.2 mg/dL, p < 0.054), before-lunch desire to eat (56.6 ± 6.8 vs 72.2 ± 4, p < 0.001), after-lunch desire to eat (5.4 ± 2.6 vs 12.3 ± 2, p < 0.01), hunger before lunch (55.4 ± 5.4 vs 73.1 ± 4.6, p < 0.001), hunger after lunch (5.8 ± 2.9 vs 11 ± 4, p < 0.01), fullness before lunch (36.6 ± 10.3 vs 18.7 ± 8.8, p < 0.001), consumption after lunch (5 ± 4.7 vs 17.5 ± 18, p < 0.05), and palatability (61 ± 5.3 vs 74.1 ± 4.1, p < 0.001). ♦ Conclusion Infection with HP is associated with anorexia, inflammation, and malnutrition in PD patients. Eradication of HP significantly improves this syndrome. Residual renal function seem to have a protective effect on appetite preservation. The present study supports the hypothesis of the involvement of inflammation in the pathogenesis of malnutrition in PD patients.


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