scholarly journals Mitochondria Distinguish Granule-Stored from de novo Synthesized Tumor Necrosis Factor Secretion in Human Mast Cells

2012 ◽  
Vol 159 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Bodi Zhang ◽  
Zuyi Weng ◽  
Nikolaos Sismanopoulos ◽  
Sharhzad Asadi ◽  
Anastasia Therianou ◽  
...  
1989 ◽  
Vol 19 (5) ◽  
pp. 939-942 ◽  
Author(s):  
Philip Scuderi ◽  
Robert T. Dorr ◽  
James D. Liddil ◽  
Paul R. Finley ◽  
Paul Meltzer ◽  
...  

Metabolism ◽  
2002 ◽  
Vol 51 (7) ◽  
pp. 887-892 ◽  
Author(s):  
A.N. Vgontzas ◽  
M. Zoumakis ◽  
D.A. Papanicolaou ◽  
E.O. Bixler ◽  
P. Prolo ◽  
...  

1998 ◽  
Vol 66 (12) ◽  
pp. 6030-6034 ◽  
Author(s):  
Michel Arock ◽  
Elaine Ross ◽  
René Lai-Kuen ◽  
Geneviève Averlant ◽  
Zhimin Gao ◽  
...  

ABSTRACT Recent studies have implicated rodent mast cells in the innate immune response to infectious bacteria. We report that cord blood-derived human mast cells (CBHMC) obtained from culture of cord blood progenitors phagocytozed and killed various gram-negative and gram-positive bacteria and simultaneously released considerable amounts of tumor necrosis factor alpha. Overall, the extent of the endocytic and exocytic response of CBHMC correlated with the number of adherent bacteria. Thus, human mast cells are intrinsically capable of mediating microbial recognition and of actively contributing to the host defense against bacteria.


1990 ◽  
Vol 19 (5-6) ◽  
pp. 453-461 ◽  
Author(s):  
Philip Scuderi ◽  
Paul R. Finley ◽  
Brian Y. Shon ◽  
John N. Udall ◽  
Denlse J. Roe ◽  
...  

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