scholarly journals Socially Modulated Cell Proliferation Is Independent of Gonadal Steroid Hormones in the Brain of the Adult Green Treefrog(Hyla cinerea)

2012 ◽  
Vol 79 (3) ◽  
pp. 170-180 ◽  
Author(s):  
Lynn M. Almli ◽  
Walter Wilczynski
Keyword(s):  
Cell Proliferation ◽  
Steroid Hormones ◽  
Gonadal Steroid Hormones ◽  
Gonadal Steroid ◽  
Hyla Cinerea ◽  
Green Treefrog ◽  
The Brain

scholarly journals Impact of sex in the prevalence and progression of glioblastomas: the role of gonadal steroid hormones

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Claudia Bello-Alvarez ◽  
Ignacio Camacho-Arroyo
Keyword(s):  
Cell Proliferation ◽  
Steroid Hormones ◽  
Physiological State ◽  
Migration And Invasion ◽  
Low Grade ◽  
Main Body ◽  
Protective Effects ◽  
Gonadal Steroid Hormones ◽  
Gonadal Steroid

Abstract Background As in other types of cancers, sex is an essential factor in the origin and progression of glioblastomas. Research in the field of endocrinology and cancer suggests that gonadal steroid hormones play an important role in the progression and prevalence of glioblastomas. In the present review, we aim to discuss the actions and mechanism triggered by gonadal steroid hormones in glioblastomas. Main body Glioblastoma is the most common malignant primary brain tumor. According to the epidemiological data, glioblastomas are more frequent in men than in women in a 1.6/1 proportion both in children and adults. This evidence, and the knowledge about sex influence over the prevalence of countless diseases, suggest that male gonadal steroid hormones, such as testosterone, promote glioblastomas growth. In contrast, a protective role of female gonadal steroid hormones (estradiol and progesterone) against glioblastomas has been questioned. Several pieces of evidence demonstrate a variety of effects induced by female and male gonadal steroid hormones in glioblastomas. Several studies indicate that pregnancy, a physiological state with the highest progesterone and estradiol levels, accelerates the progression of low-grade astrocytomas to glioblastomas and increases the symptoms associated with these tumors. In vitro studies have demonstrated that progesterone has a dual role in glioblastoma cells: physiological concentrations promote cell proliferation, migration, and invasion while very high doses (out physiological range) reduce cell proliferation and increases cell death. Conclusion Gonadal steroid hormones can stimulate the progression of glioblastomas through the increase in proliferation, migration, and invasion. However, the effects mentioned above depend on the concentrations of these hormones and the receptor involved in hormone actions. Estradiol and progesterone can exert promoter or protective effects while the role of testosterone has been always associated to glioblastomas progression.

scholarly journals Functional neuroimaging as a direct probe of the effects of gonadal steroid hormones on the brain

2002 ◽  
Vol 4 (2) ◽  
pp. 192-195
Keyword(s):  
Steroid Hormones ◽  
Animal Studies ◽  
Functional Neuroimaging ◽  
Functional Brain Imaging ◽  
Neural Function ◽  
Gonadal Steroid Hormones ◽  
Gonadal Steroid ◽  
Neurophysiological Data ◽  
Health And Disease ◽  
The Brain

There is considerable evidence from animal studies dial gonadal steroid hormones modulate neuronal activity and affect behavior. In humans, however, the behavioral and cognitive evidence has not been conclusive, and, until recently, there have been few direct neurophysiological data. Functional brain imaging offers unique opportunities to characterize in humans the effects of gonadal steroid hormones on basic neurobiological parameters, such as neuronal metabolism and neurochemical systems, and to clarify the interactions between these hormones and cognition and mood regulation in health and disease. The most commonly used tools within the considerable armamentarium available for such research and the parameters of neural function that they can access are briefly reviewed here.

scholarly journals Effect of gonadal steroid hormones on formalin-induced temporomandibular joint inflammation

2012 ◽  
Vol 16 (2) ◽  
pp. 204-216 ◽  
Author(s):  
K.E. Torres-Chávez ◽  
J.M. Sanfins ◽  
J.T. Clemente-Napimoga ◽  
A. Pelegrini-Da-Silva ◽  
C.A. Parada ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Steroid Hormones ◽  
Joint Inflammation ◽  
Gonadal Steroid Hormones ◽  
Gonadal Steroid ◽  
Temporomandibular Joint Inflammation

scholarly journals Ovarian Activity and Pregnancy in the Siberian Tiger, Panthera tigris altaica, Assessed by Fecal Gonadal Steroid Hormones Analyses

2007 ◽  
Vol 69 (5) ◽  
pp. 569-571 ◽  
Author(s):  
Heri Dwi PUTRANTO ◽  
Satoshi KUSUDA ◽  
Kayo INAGAKI ◽  
Gaku KUMAGAI ◽  
Rie ISHII-TAMURA ◽  
...  
Keyword(s):  
Steroid Hormones ◽  
Ovarian Activity ◽  
Panthera Tigris ◽  
Gonadal Steroid Hormones ◽  
Gonadal Steroid ◽  
Siberian Tiger ◽  
Panthera Tigris Altaica
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