scholarly journals Developmental Expression of the Pluripotency Factor Sal-Like Protein 4 in the Monkey, Human and Mouse Testis: Restriction to Premeiotic Germ Cells

2012 ◽  
Vol 196 (3) ◽  
pp. 206-220 ◽  
Author(s):  
K. Eildermann ◽  
N. Aeckerle ◽  
K. Debowski ◽  
M. Godmann ◽  
H. Christiansen ◽  
...  
Keyword(s):  
Germ Cells ◽  
Mouse Testis ◽  
Developmental Expression ◽  
Pluripotency Factor ◽  
Human And Mouse

scholarly journals Peroxisomes in Human and Mouse Testis: Differential Expression of Peroxisomal Proteins in Germ Cells and Distinct Somatic Cell Types of the Testis1

2007 ◽  
Vol 77 (6) ◽  
pp. 1060-1072 ◽  
Author(s):  
Anca Nenicu ◽  
Georg H. Lüers ◽  
Werner Kovacs ◽  
Martin Bergmann ◽  
Eveline Baumgart-Vogt
Keyword(s):  
Somatic Cell ◽  
Differential Expression ◽  
Germ Cells ◽  
Cell Types ◽  
Mouse Testis ◽  
Human And Mouse

Binucleate Spermiogenesis in the Mouse

1972 ◽  
Vol 30 ◽  
pp. 112-113
Author(s):  
John J. Wolosewick
Keyword(s):  
Electron Microscopy ◽  
Phosphate Buffer ◽  
Seminiferous Epithelium ◽  
Mouse Testis ◽  
Germinal Epithelium ◽  
Intercellular Bridges ◽  
Adult Mice ◽  
Cervical Dislocation ◽  
Human And Mouse

Classically, the male germinal epithelium is depicted as synchronously developing uninucleate spermatids conjoined by intercellular bridges. Recently, binucleate and multinucleate spermatids from human and mouse testis have been reported. The present paper describes certain developmental events in one type of binucleate spermatid in the seminiferous epithelium of the mouse.Testes of adult mice (ABP Jax) were removed from the animals after cervical dislocation and placed into 2.5% glutaraldehyde/Millonig's phosphate buffer (pH 7.2). Testicular capsules were gently split and separated, exposing the tubules. After 15 minutes the tissue was carefully cut into cubes (approx. 1mm), fixed for an additional 45 minutes and processed for electron microscopy.

scholarly journals FLIP is expressed in mouse testis and protects germ cells from apoptosis

2003 ◽  
Vol 10 (2) ◽  
pp. 175-184 ◽  
Author(s):  
C Giampietri ◽  
S Petrungaro ◽  
P Coluccia ◽  
A D'Alessio ◽  
D Starace ◽  
...  
Keyword(s):  
Germ Cells ◽  
Mouse Testis

Developing germ cells in mouse testis express pheromone receptors

FEBS Letters ◽  
2001 ◽  
Vol 488 (3) ◽  
pp. 139-144 ◽  
Author(s):  
Hiroyuki Tatsura ◽  
Hiroshi Nagao ◽  
Atsushi Tamada ◽  
Shoichi Sasaki ◽  
Kenjiro Kohri ◽  
...  
Keyword(s):  
Germ Cells ◽  
Mouse Testis

Developmental expression of c-kit, a proto-oncogene encoded by the W locus

Development ◽  
1990 ◽  
Vol 109 (4) ◽  
pp. 911-923 ◽  
Author(s):  
A. Orr-Urtreger ◽  
A. Avivi ◽  
Y. Zimmer ◽  
D. Givol ◽  
Y. Yarden ◽  
...  
Keyword(s):  
Germ Cells ◽  
Receptor Tyrosine Kinase ◽  
Germ Line ◽  
Primordial Germ Cells ◽  
Mouse Embryos ◽  
Developmental Expression ◽  
Male Germ Line ◽  
Polypeptide Growth Factors ◽  
Adult Ovary

Developmental expression of the c-kit proto-oncogene, a receptor tyrosine kinase encoded by the W locus, was investigated by in situ hybridization in normal mouse embryos. Early after implantation transcripts were detectable only in the maternal placenta (6 1/2-7 1/2 days p.c.). Subsequently (8 1/2 days p.c.) numerous ectodermal (neural tube, sensory placodes) and endodermal (embryonic gut) derivatives expressed c-kit. Later transcripts were detected also in the blood islands of the yolk sac and in the embryonic liver, the main sites of embryonic hemopoiesis. Around midgestation, transcripts accumulated in the branchial pouches and also in primordial germ cells of the genital ridges. This complex pattern of expression remained characteristic also later in gestation, when c-kit was expressed in highly differentiated structures of the craniofacial area, in presumptive melanoblasts and in the CNS. In the adult ovary, maternal c-kit transcripts were detected. They were present in the oocytes of both immature and mature ovarian follicles, but not in the male germ line, where c-kit expression may be down regulated. Thus, c-kit activity is complex and appears in multiple tissues including those that also display defects in mutations at the W locus where c-kit is encoded. Correlation between W phenotypes and c-kit expression, as well as the regulation of the complex and multiple expression of polypeptide growth factors and receptors, is discussed.

Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells

Development ◽  
1994 ◽  
Vol 120 (7) ◽  
pp. 1759-1766 ◽  
Author(s):  
K. Yomogida ◽  
H. Ohtani ◽  
H. Harigae ◽  
E. Ito ◽  
Y. Nishimune ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Developmental Stage ◽  
Sertoli Cell ◽  
Germ Cells ◽  
Sertoli Cells ◽  
Transcriptional Activation ◽  
Germ Line ◽  
Mouse Testis ◽  
Seminiferous Tubules ◽  
Specific Expression

GATA-1 is an essential factor for the transcriptional activation of erythroid-specific genes, and is also abundantly expressed in a discrete subset of cells bordering the seminiferous epithelium in tubules of the murine testis. In examining normal and germ-line defective mutant mice, we show here that GATA-1 is expressed only in the Sertoli cell lineage in mouse testis. GATA-1 expression in Sertoli cells is induced concomitantly with the first wave of spermatogenesis, and GATA-1-positive cells are uniformly distributed among all tubules during prepubertal testis development. However, the number of GATA-1-positive cells declines thereafter and were found only in the peripheral zone of seminiferous tubules in stages VII, VIII and IX of spermatogenesis in the adult mouse testis. In contrast, virtually every Sertoli cell in mutant W/Wv, jsd/jsd or cryptorchid mice (all of which lack significant numbers of germ cells) expresses GATA-1, thus showing that the expression of this transcription factor is negatively controlled by the maturing germ cells. These observations suggest that transcription factor GATA-1 is a developmental stage- and spermatogenic cycle-specific regulator of gene expression in Sertoli cells.

A novel spermatogenesis-specific uPAR gene expressed in human and mouse testis

2006 ◽  
Vol 342 (4) ◽  
pp. 1223-1227 ◽  
Author(s):  
Xiaokun Teng ◽  
Jun Yang ◽  
Yong Xie ◽  
Zumei Ni ◽  
Ruiying Hu ◽  
...  
Keyword(s):  
Mouse Testis ◽  
Human And Mouse
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