scholarly journals Aleukemic Leukemia Cutis Manifesting with Disseminated Nodular Eruptions and a Plaque Preceding Acute Monocytic Leukemia: A Case Report

2011 ◽  
Vol 4 (3) ◽  
pp. 547-554 ◽  
Author(s):  
Ipek Yonal ◽  
Fehmi Hindilerden ◽  
Raif Coskun ◽  
Oner Ibrahim Dogan ◽  
Meliha Nalcaci
2011 ◽  
Vol 28 (2) ◽  
pp. 147-149
Author(s):  
Chihiro Kawakami ◽  
Akiko Inoue ◽  
Kimitaka Takitani ◽  
Takayuki Ikemoto ◽  
Noboru Yonetani ◽  
...  

2018 ◽  
Vol 10 (4) ◽  
pp. 119-123
Author(s):  
Dušan Mihajlović ◽  
Miroslav Dinić ◽  
Željko Mijušković ◽  
Nenad Petrov ◽  
Olga Radić Tasić ◽  
...  

Abstract Leukemia cutis is a specific skin lesion which is characterized by diffuse infiltration of neoplastic cells and can occur in all types of leukemia. Leukemia cutis can have varied cutaneous presentations such as papules, macules, nodules, plaques and ulcers. We report a case of 52-year-old woman who presented with erythematous macules and papules over her trunk, thighs and upper arms. A skin punch biopsy showed monomorphic, perivascular and periadnexal infiltration by the cells positive for CD45, CD15, CD68 and lysozyme. According to the subsequent bone marrow biopsy and immunophenotypic analysis of peripheral blood cells, the diagnosis of acute monocytic leukemia (FAB AML-M5b) was made. In our case, the first clinical sign suggestive of the diagnosis of leukemia was the presence of erythematous macules and papules. Therefore, we believe that leukemia cutis should be taken into consideration in the differential diagnosis of maculopapular rush on the trunk, upper arms and leg


2016 ◽  
Vol 28 (4) ◽  
pp. 418-420
Author(s):  
Sonali R Gawai ◽  
VG Binesh ◽  
Ambooken Betsy ◽  
KT Jisha

Leukemia cutis is seen in around 20% of acute monocytic leukemia. They usually present as papules or nodules or infiltrated plaques but ulceration is uncommon. A 28-year-old female presented with multiple painless indurated genital ulcers of three weeks’ duration with low-grade fever, gum hyperplasia, and generalized lymphadenopathy. Tissue smear from the edge of the ulcer showed atypical monocytes suggestive of leukemic infiltrate which was further confirmed by peripheral smear and bone marrow aspirate. Herein, we report a case of acute monocytic leukemia (AML) with leukemia cutis presenting initially with genital ulcers simulating chancre.


2007 ◽  
Vol 01 (02) ◽  
pp. 111-114 ◽  
Author(s):  
Serhat Demirer ◽  
Hakan Özdemir ◽  
Mehmet Şencanc ◽  
Ismail Marakoğlud

ABSTRACTAcute Myeloblastic Leukemia (AML) is a malignant disease of bone marrow. Due to its high morbidity rate, early diagnosis and appropriate medical therapy is essential. Rapidly forming gingival hyperplasia is usually the first sign of this disease. This case report describes a 17-year-old female who presented rapid gingival overgrowth together with gingival bleeding in only two weeks time. A medical consultation was asked from hematology clinics and after a detailed medical examination Acute Monocytic Leukemia (FAB M5) was rendered. Chemotherapy was the choice of treatment. The patient responded well to chemotherapeutic induction regimen and after two months of medical therapy disease remised and gingival hyperplasia regressed. This case report shows that the gingival hyperplasia may represent an initial manifestation of an underlying systemic disease. Also, early medical therapy in acute monocytic leukemia may resolve the gingival hyperplasia that companies the disease progression. (Eur J Dent 2007;2:111-114)


2013 ◽  
Vol 6 (5) ◽  
pp. 1319-1322
Author(s):  
DONG KEUN SEOK ◽  
SAE YOON KEE ◽  
SOON YOUNG KO ◽  
JUNG HWA LEE ◽  
HYE YOUNG KIM ◽  
...  

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