scholarly journals Combined Gene and Protein Expression of Hormone-Sensitive Lipase and Adipose Triglyceride Lipase, Mitochondrial Content, and Adipocyte Size in Subcutaneous and Visceral Adipose Tissue of Morbidly Obese Men

Obesity Facts ◽  
2011 ◽  
Vol 4 (5) ◽  
pp. 407-416 ◽  
Author(s):  
Hélène De Naeyer ◽  
D. Margriet Ouwens ◽  
Yves Van Nieuwenhove ◽  
Piet Pattyn ◽  
Leen M. ‘t Hart ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Hormone Sensitive Lipase ◽  
Morbidly Obese ◽  
Adipose Triglyceride Lipase ◽  
Adipocyte Size ◽  
Mitochondrial Content ◽  
Gene And Protein Expression ◽  
Hormone Sensitive ◽  
Visceral Adipose

Trans-palmitoleic Acid Reduces Adiposity via Increased Lipolysis in a Rodent Model of Diet-Induced Obesity

2021 ◽  
pp. 1-24
Author(s):  
L. Irasema Chávaro-Ortiz ◽  
Brenda D. Tapia-Vargas ◽  
Mariel Rico-Hidalgo ◽  
Ruth Gutiérrez-Aguilar ◽  
María E. Frigolet
Keyword(s):  
Adipose Tissue ◽  
Lipid Metabolism ◽  
Visceral Adipose Tissue ◽  
High Fat Diet ◽  
Palmitoleic Acid ◽  
Rodent Model ◽  
Adipocyte Size ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Visceral Adipose

Abstract Obesity is defined as increased adiposity, which leads to metabolic disease. The growth of adipose tissue depends on its capacity to expand, through hyperplasia or hypertrophy, in order to buffer energy surplus. Also, during the establishment of obesity, adipose tissue expansion reflects adipose lipid metabolism (lipogenesis and/or lipolysis). It is well known that dietary factors can modify lipid metabolism promoting or preventing the development of metabolic abnormalities that concur with obesity. Trans-palmitoleic acid (TP), a biomarker of dairy consumption, has been associated with reduced adiposity in clinical studies. Thus, we aimed to evaluate the effect of TP over adiposity and lipid metabolism-related genes in a rodent model of diet-induced obesity (DIO). To fulfil this aim, we fed C57BL/6 mice with a Control or a High Fat diet, added with or without TP (3g/kg diet), during 11 weeks. Body weight and food intake were monitored, fat pads were weighted, histology of visceral adipose tissue was analysed, and lipid metabolism-related gene expression was explored by qPCR. Results show that TP consumption prevented weight gain induced by high fat diet, reduced visceral adipose tissue weight, and adipocyte size, while increasing the expression of lipolytic molecules. In conclusion, we show for the first time that TP influences adipose tissue metabolism, specifically lipolysis, resulting in decreased adiposity and reduced adipocyte size in a DIO mice model.

Overexpression of hepatic 5α-reductase and 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue is associated with hyperinsulinemia in morbidly obese patients

Metabolism ◽  
2011 ◽  
Vol 60 (12) ◽  
pp. 1775-1780 ◽  
Author(s):  
René Baudrand ◽  
José Miguel Domínguez ◽  
Cristian A. Carvajal ◽  
Arnoldo Riquelme ◽  
Carmen Campino ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Hydroxysteroid Dehydrogenase ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Visceral Adipose

scholarly journals Erratum to: SIRT1 Transcription Is Decreased in Visceral Adipose Tissue of Morbidly Obese Patients with Severe Hepatic Steatosis

2010 ◽  
Vol 20 (6) ◽  
pp. 831-831
Author(s):  
Cíntia dos Santos Costa ◽  
Thais Ortiz Hammes ◽  
Francieli Rohden ◽  
Rogério Margis ◽  
Josiane Woutheres Bortolotto ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Hepatic Steatosis ◽  
Visceral Adipose Tissue ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Visceral Adipose

scholarly journals Age and gender specific estimation of visceral adipose tissue amounts from radiological images in morbidly obese patients

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Nicolas Linder ◽  
Alexander Schaudinn ◽  
Nikita Garnov ◽  
Matthias Blüher ◽  
Arne Dietrich ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Age And Gender ◽  
Radiological Images ◽  
And Gender ◽  
Visceral Adipose ◽  
Gender Specific

scholarly journals Effect of Aerobic Training and Octopamine Supplementation on the Expression of Octopamine Receptors in the Visceral Adipose Tissue of Rats Exposed to Deep Fried Oils

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mahnaz Vesali ◽  
Mohammad Ali Azarbayjani ◽  
Maghsood Peeri
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Aerobic Training ◽  
Hormone Sensitive Lipase ◽  
Interactive Effects ◽  
Octopamine Receptors ◽  
Two Factors ◽  
Male Wistar Rats ◽  
Healthy Control ◽  
Visceral Adipose

Background: The use of deep fried oils (DFOs) to cook foods is associated with numerous diseases. Although the role of physical activity and some supplements on fat lipolysis has been established, the effect of aerobic training (AT) and octopamine (Oct) on octopamine receptor-dependent lipolysis pathway is not well understood. Objectives: The present study aimed to investigate the effect of AT and Oct supplementation on the expression of Oct receptors in the visceral adipose tissue of DFO-exposed rats. Methods: In this experimental study, 30 male Wistar rats were divided into (1) healthy control (C), (2) DFO, (3) DFO + Oct, (4) DFO + AT, and (5) DFO + Oct + AT groups. Aerobic training was performed for four weeks, five sessions per week at an intensity of 16 - 26 m/min and equivalent to 50% - 65% VO2max, and Otc supplement was interperitoneally injected at 81 µmol/kg five days a week. Results: Aerobic training and Oct supplementation increased tyramin-R and hormone-sensitive lipase (HSL) (P ≤ 0.05), while Oct significantly decreased G protein-coupled receptors (GPCR) (P ≤ 0.05). Also, the interaction of AT and Oct on GPCR reduction was significant (P ≤ 0.05). Conclusions: It seems that AT and Otc alone improve octopamine receptors and lipolysis markers in the visceral adipose tissue of DFO-treated rats, but these two factors have no interactive effects on this pathway.

SIRT1 Transcription Is Decreased in Visceral Adipose Tissue of Morbidly Obese Patients with Severe Hepatic Steatosis

2009 ◽  
Vol 20 (5) ◽  
pp. 633-639 ◽  
Author(s):  
Cíntia dos Santos Costa ◽  
Thais Ortiz Hammes ◽  
Francieli Rohden ◽  
Rogério Margis ◽  
Josiane Woutheres Bortolotto ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Hepatic Steatosis ◽  
Visceral Adipose Tissue ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Visceral Adipose

Adipose Tissue Distribution and Quantification of PPARβ/δ and PPARγ1-3 mRNAs: Discordant Gene Expression in Subcutaneous, Retroperitoneal and Visceral Adipose Tissue of Morbidly Obese Patients

2007 ◽  
Vol 17 (7) ◽  
pp. 934-940 ◽  
Author(s):  
Josiane Woutheres Bortolotto ◽  
Rogério Margis ◽  
Ângela Cristine Bersch Ferreira ◽  
Alexandre Vontobel Padoin ◽  
Cláudio Cora Mottin ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Tissue Distribution ◽  
Visceral Adipose Tissue ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Adipose Tissue Distribution ◽  
Visceral Adipose
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