Prior Use of Antiplatelet Therapy Can Be Associated with a Higher Chance for Early Recanalization of the Occluded Middle Cerebral Artery in Acute Stroke Patients Treated with Intravenous Thrombolysis

2012 ◽  
Vol 67 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Daniel Šaňák ◽  
Martin Kuliha ◽  
Roman Herzig ◽  
Martin Roubec ◽  
David Školoudík ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Middle Cerebral Artery ◽  
Antiplatelet Therapy ◽  
Cerebral Artery ◽  
Intravenous Thrombolysis ◽  
Stroke Patients ◽  
Prior Use

Hypoperfusion in lenticulostriate arteries territory related to unexplained early neurological deterioration after intravenous thrombolysis

2019 ◽  
Vol 14 (3) ◽  
pp. 306-309 ◽  
Author(s):  
Ying Zhou ◽  
Wansi Zhong ◽  
Anli Wang ◽  
Wanyun Huang ◽  
Shenqiang Yan ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Acute Ischemic Stroke ◽  
Cerebral Artery ◽  
Intravenous Thrombolysis ◽  
Neurological Deterioration ◽  
Terminal Branch ◽  
Stroke Patients ◽  
Lenticulostriate Arteries ◽  
Early Neurological Deterioration

Background Early neurological deterioration occurs in approximately 10% acute ischemic stroke patients after thrombolysis. Over half of the early neurological deterioration occurred without known causes and is called unexplained early neurological deterioration. Aims We aimed to explore the development of early neurological deterioration at 24 h after thrombolysis, and whether it could be predicted by the presence of baseline hypoperfusion in lenticulostriate arteries territory in acute ischemic stroke patients. Methods We retrospectively reviewed our prospectively collected database of acute ischemic stroke patients in the unilateral middle cerebral artery territory who had baseline perfusion image and received thrombolysis. Unexplained early neurological deterioration was defined as ≥ 2 points increase of National Institutes of Health Stroke Scale (NIHSS) from baseline to 24 h, without known causes. Hypoperfusion lesions in different territories were identified on perfusion maps. Results A total of 306 patients were included in analysis. Patients with pure lenticulostriate arteries hypoperfusion (defined as the presence of hypoperfusion in lenticulostriate artery territory, but not in middle cerebral artery terminal branch territory) were more likely to have unexplained early neurological deterioration than others (27.6% vs. 6.1%; OR, 5.974; p = 0.001), after adjusting for age, baseline NIHSS and onset to treatment time. Conclusions Patients presenting hypoperfusion in pure lenticulostriate arteries territory were easier to experience unexplained early neurological deterioration.

Intravenous thrombolysis in stroke patients with hyperdense middle cerebral artery sign

2009 ◽  
Vol 16 (2) ◽  
pp. 162-167 ◽  
Author(s):  
D. Georgiadis ◽  
F. Wirz ◽  
H-C. von Büdingen ◽  
P. Valko ◽  
M. Hund-Georgiadis ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Intravenous Thrombolysis ◽  
Stroke Patients ◽  
Hyperdense Middle Cerebral Artery

scholarly journals Intravenous Thrombolysis of Occlusion in the Middle Cerebral and Retinal Arteries from Presumed Ventricular Myxoma

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Cheung-Ter Ong ◽  
Rei-Yeuh Chang
Keyword(s):  
Emergency Department ◽  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Intravenous Thrombolysis ◽  
Case Description ◽  
Stroke Patients ◽  
Tissue Plasminogen ◽  
The Right

Background. Although thrombolytic therapy has been shown to be beneficial to stroke patients, the effectiveness of intravenous thrombolysis in ischemic stroke patients with ventricle myxoma is unknown.Case Description. A 22-year-old woman with left hemiplegia was sent to the emergency department at a teaching hospital. The magnetic resonance angiography showed occlusion of the right middle cerebral artery, and the echocardiography showed a mass in the left ventricle. Intravenous recombined tissue plasminogen activator (rt-PA) was administrated, and the postthrombolysis transcranial Doppler exam showed that her right middle cerebral artery was circulative. The patient's condition improved gradually, and no complication was observed up to 16 months of follow-up.Conclusion. Intravenous rt-PA is a reasonable treatment for stroke patients with ventricle myxoma.

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