Novel Therapeutic Approach for Neurodegenerative Pathologies: Multitarget Iron-Chelating Drugs Regulating Hypoxia-Inducible Factor 1 Signal Transduction Pathway

Orly Weinreb; Tamar Amit; Silvia Mandel; Moussa B.H. Youdim

doi:10.1159/000332597

Novel Therapeutic Approach for Neurodegenerative Pathologies: Multitarget Iron-Chelating Drugs Regulating Hypoxia-Inducible Factor 1 Signal Transduction Pathway

Neurodegenerative Diseases ◽

10.1159/000332597 ◽

2012 ◽

Vol 10 (1-4) ◽

pp. 112-115 ◽

Cited By ~ 9

Author(s):

Orly Weinreb ◽

Tamar Amit ◽

Silvia Mandel ◽

Moussa B.H. Youdim

Keyword(s):

Signal Transduction ◽

Therapeutic Approach ◽

Hypoxia Inducible Factor ◽

Signal Transduction Pathway ◽

Transduction Pathway ◽

Hypoxia Inducible Factor 1 ◽

Novel Therapeutic

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Hypoxia-inducible Factor 1α Regulates a SOCS3-STAT3-Adiponectin Signal Transduction Pathway in Adipocytes

Journal of Biological Chemistry ◽

10.1074/jbc.m112.426338 ◽

2012 ◽

Vol 288 (6) ◽

pp. 3844-3857 ◽

Cited By ~ 41

Author(s):

Changtao Jiang ◽

Jung-Hwan Kim ◽

Fei Li ◽

Aijuan Qu ◽

Oksana Gavrilova ◽

...

Keyword(s):

Signal Transduction ◽

Hypoxia Inducible Factor ◽

Signal Transduction Pathway ◽

Transduction Pathway ◽

Hypoxia Inducible Factor 1Α

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Use of hypoxia-inducible factor signal transduction pathway to measure O2 levels and modulate growth factor pathways

Wound Repair and Regeneration ◽

10.1046/j.1524-475x.2003.11620.x ◽

2003 ◽

Vol 11 (6) ◽

pp. 496-503 ◽

Cited By ~ 4

Author(s):

Jon E. Mogford ◽

Nakshatra K. Roy ◽

Kevin J. Cross ◽

Thomas A. Mustoe

Keyword(s):

Signal Transduction ◽

Growth Factor ◽

Hypoxia Inducible Factor ◽

Signal Transduction Pathway ◽

Transduction Pathway ◽

Growth Factor Pathways

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159: Deletion of SM-B, the High Atpase Isoform of Myosin, Upregulates the PKC-Mediated Signal Transduction Pathway in the Urinary Bladder Smooth Muscle

The Journal of Urology ◽

10.1016/s0022-5347(18)32426-1 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 51-51

Author(s):

Joseph A. Hypolite ◽

Shaohua Chang ◽

Edward Labelle ◽

Gopal J. Babu ◽

Muthu Periasamy ◽

...

Keyword(s):

Signal Transduction ◽

Smooth Muscle ◽

Urinary Bladder ◽

Signal Transduction Pathway ◽

Transduction Pathway ◽

Bladder Smooth Muscle ◽

Urinary Bladder Smooth Muscle

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1628: Direct Regulation of Prostate Blood Flow By Vascular Endothelial Growth Factor and its Participation in The Signal Transduction Pathway of Androgenic Prostate Blood Flow Regulation

The Journal of Urology ◽

10.1016/s0022-5347(18)38836-0 ◽

2004 ◽

Vol 171 (4S) ◽

pp. 430-430

Author(s):

Seiji Arai ◽

Yasuhiro Shibata ◽

Bunzo Kashiwagi ◽

Yoshitatsu Fukabori ◽

Kazuhiro Suzuki ◽

...

Keyword(s):

Signal Transduction ◽

Vascular Endothelial Growth Factor ◽

Blood Flow ◽

Growth Factor ◽

Signal Transduction Pathway ◽

Flow Regulation ◽

Vascular Endothelial ◽

Transduction Pathway ◽

Endothelial Growth Factor ◽

Direct Regulation

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A PI-3′ kinase- and ets-dependent signal transduction pathway regulates anchorage-independent growth and tumorigenicity in human breast and female reproductive tract carcinomas

Journal of the Society for Gynecologic Investigation ◽

10.1016/s1071-5576(97)86079-0 ◽

1998 ◽

Vol 5 (1) ◽

pp. 39A-39A

Author(s):

B KACINSKI

Keyword(s):

Signal Transduction ◽

Reproductive Tract ◽

Signal Transduction Pathway ◽

Female Reproductive Tract ◽

Transduction Pathway ◽

Human Breast ◽

Anchorage Independent Growth ◽

Dependent Signal

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Faculty Opinions recommendation of Ethylene inhibits the Nod factor signal transduction pathway of Medicago truncatula.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000965.16059 ◽

2001 ◽

Author(s):

Allan Downie

Keyword(s):

Signal Transduction ◽

Medicago Truncatula ◽

Signal Transduction Pathway ◽

Transduction Pathway ◽

Nod Factor

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Faculty Opinions recommendation of The Ras1-mitogen-activated protein kinase signal transduction pathway regulates synaptic plasticity through fasciclin II-mediated cell adhesion.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1005655.67206 ◽

2002 ◽

Author(s):

Morgan Sheng

Keyword(s):

Signal Transduction ◽

Cell Adhesion ◽

Synaptic Plasticity ◽

Protein Kinase ◽

Signal Transduction Pathway ◽

Mitogen Activated Protein Kinase ◽

Transduction Pathway ◽

Mitogen Activated Protein

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Faculty Opinions recommendation of The ARG1-LIKE2 gene of Arabidopsis functions in a gravity signal transduction pathway that is genetically distinct from the PGM pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017529.203285 ◽

2004 ◽

Author(s):

Emmanuel Liscum

Keyword(s):

Signal Transduction ◽

Signal Transduction Pathway ◽

Transduction Pathway ◽

Gravity Signal

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Faculty Opinions recommendation of A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017235.203231 ◽

2004 ◽

Author(s):

Ron Prywes

Keyword(s):

Signal Transduction ◽

Signal Transduction Pathway ◽

Tnf Alpha ◽

Transduction Pathway ◽

Nf Kappa B ◽

Functional Map

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Faculty Opinions recommendation of Salt stress responses in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1096008.551993 ◽

2007 ◽

Author(s):

Ramón Serrano

Keyword(s):

Signal Transduction ◽

Endoplasmic Reticulum ◽

Salt Stress ◽

Endoplasmic Reticulum Stress ◽

Stress Responses ◽

Signal Transduction Pathway ◽

Stress Signaling ◽

Transduction Pathway

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