Combined Fine Needle Aspiration Biopsy, and Immunophenotypic and Genotypic Approach to Posttransplantation Lymphoproliferative Disorders

1998 ◽  
Vol 42 (4) ◽  
pp. 869-874 ◽  
Author(s):  
Brian T. Collins ◽  
Ricardo R. Ramos ◽  
Leonard E. Grosso
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Lymphoproliferative Disorders ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

LYMPHOID INFILTRATION IN TOXIC GOITRES STUDIED WITH FINE NEEDLE ASPIRATION BIOPSY

1972 ◽  
Vol 71 (3) ◽  
pp. 480-490 ◽  
Author(s):  
Göran Nilsson
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Lymphoid Cells ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Needle Aspiration Biopsy ◽  
Lymphoid Infiltration ◽  
Long Acting

ABSTRACT Cytodiagnostic fine needle aspiration biopsy specimens from toxic goitres were studied for signs of lymphoid infiltration. Comparison with histological sections of specimens obtained by surgery showed that an excess of lymphoid cells in the aspirate smears corresponded to a large number of lymphoid foci in these sections. Excess of lymphoid cells in the fine needle aspirates was also positively correlated with the occurrence of circulating thyroid antibodies against thyroglobulin and/or cytoplasmic antigen, but not with the presence of the long-acting thyroid stimulating factor, LATS. It also varied with age in that it was most common in the youngest patients and in patients between 40–55 years, while lymphoid infiltration was seldom seen in patients over 55 years. A finding of practical clinical interest was that in toxic goitres with cytological signs of lymphoid infiltration hyperthyroidism had less tendency to recur after treatment with thiocarbamide drugs than in those without such signs.

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