scholarly journals Activation of Human Neutrophils by Oleic Acid Involves the Production of Reactive Oxygen Species and a Rise in Cytosolic Calcium Concentration: a Comparison with N-6 Polyunsaturated Fatty Acids

2011 ◽  
Vol 28 (2) ◽  
pp. 329-338 ◽  
Author(s):  
Celia Carrillo ◽  
María del Mar Cavia ◽  
Hennie Roelofs ◽  
Geert Wanten ◽  
Sara R. Alonso-Torre
Keyword(s):  
Reactive Oxygen Species ◽  
Fatty Acids ◽  
Oleic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Calcium Concentration ◽  
Reactive Oxygen ◽  
Cytosolic Calcium ◽  
Human Neutrophils ◽  
Oxygen Species ◽  
Cytosolic Calcium Concentration

scholarly journals Nitro-Oleic Acid Induced Reactive Oxygen Species Formation and Plant Defense Signaling in Tomato Cell Suspensions

2018 ◽  
Author(s):  
Andrés Arruebarrena Di Palma ◽  
Luciano M. Di Fino ◽  
Sonia R. Salvatore ◽  
Juan Martín D’Ambrosio ◽  
Gustavo Esteban Gergoff Grozeff ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Reactive Oxygen Species ◽  
Fatty Acids ◽  
Oleic Acid ◽  
Nitrogen Dioxide ◽  
Plant Defense ◽  
Reduced Glutathione ◽  
Reactive Oxygen ◽  
Ros Production ◽  
Oxygen Species

ABSTRACTNitrated fatty acids (NO2-FAs) are formed by the addition reaction of nitric oxide- and nitrite-derived nitrogen dioxide with unsaturated fatty acids. Nitrated fatty acids act as signaling molecules in mammals through the formation of covalent adducts with cellular thiols. The study of NO2-FAs in plant systems constitutes an interesting and emerging area. The presence of NO2-FA has been reported in olives, peas, rice and in Arabidopsis. To gain a better understanding of the role of NO2-FA on plant physiology, we analyzed the effects of exogenous application of nitro-oleic acid (NO2-OA) to tomato cell cultures. We found that NO2-OA induced reactive oxygen species (ROS) production in a dose-dependent manner via activation of NADPH oxidases, which requires calcium entry from the extracellular compartment and protein kinase activation, a mechanism that resembles the plant defense responses. NO2-OA-induced ROS production, expression of plant defense genes and led to cell death. The mechanism of action of NO2-OA involves a reduction in the glutathione cellular pool and covalently addition reactions with protein thiols and reduced glutathione. Altogether, these results indicate that NO2-OA triggers responses associated with plant defense, revealing its possible role as a signal molecule in biotic stress.Abbreviations•NO2nitrogen dioxide•NOnitric oxideFAfatty acidGSHreduced glutathioneH2O2hydrogen peroxydeNO2-FAnitro fatty acidsNO2-Lnnitro-linolenic acidNO2-OAnitro-oleic acidOAoleic acidROSreactive oxygen species

scholarly journals EFFECTS OF FATTY ACIDS ON PRODUCTION OF REACTIVE OXYGEN SPECIES (ROS) BY SKELETAL MUSCLE CELLS

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Renato Tadeu Nachbar ◽  
Augusto Ducati Luchessi ◽  
Tavane David Cambiaghi ◽  
Rafael Herling Lambertucci ◽  
Sandro Massao Hirabara ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Skeletal Muscle ◽  
Fatty Acids ◽  
Reactive Oxygen ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Oxygen Species
Sign in / Sign up

Export Citation Format

Share Document