Effect of Gap Geometry on Secondary Caries Wall Lesion Development

2011 ◽  
Vol 45 (4) ◽  
pp. 346-352 ◽  
Author(s):  
H.M. Nassar ◽  
C. González-Cabezas
Keyword(s):  
Lesion Development ◽  
Secondary Caries ◽  
Wall Lesion

Chlorhexidine, a Matrix Metalloproteinase Inhibitor and the Development of Secondary Caries Wall Lesions in a Microcosm Biofilm Model

2018 ◽  
Vol 53 (1) ◽  
pp. 107-117
Author(s):  
Tamires T. Maske ◽  
Nicolien K. Kuper ◽  
Maximiliano S. Cenci ◽  
Marie-Charlotte D.N.J.M. Huysmans
Keyword(s):  
Matrix Metalloproteinase ◽  
Matrix Metalloproteinase Inhibitor ◽  
Lesion Development ◽  
Secondary Caries ◽  
Mmp Inhibitor ◽  
Biofilm Model ◽  
Wall Lesion ◽  
Composite Samples ◽  
Wall Lesions

This study investigated the role of a matrix metalloproteinase (MMP) inhibitor (CHX 2%) in the development of secondary caries wall lesions in different interface conditions with small (run 1) and wider gaps (run 2). Dentin discs were restored and pretreated with or without CHX 2%. In run 1, interfaces were made with gaps of 30, 60, or 90 µm. Interfaces with composite placed directly onto the dentin were either bonded (Adper Single Bond 2) or not bonded. In run 2, interfaces were made with gaps of 100 µm, with or without adhesive on the composite side (CLEARFIL SE Bond). Interfaces were either bonded or not bonded, as in run 1. Microcosm biofilms were grown on dentin-composite samples for 14 days. Caries lesion outcomes were analyzed by transversal wavelength-independent microradiography at 3 locations: the outer surface, and the interface wall at a distance of 200 and 500 µm from the gap entrance. Linear regression analyses showed that pretreatment with MMP inhibitor did not influence progression of the wall lesion at any location (p ≥ 0.218). Interfaces with intentional gaps showed positive and significant effect on the wall lesion progression at 200 µm from the gap entrance (p ≤ 0.005). A small trend of increase in wall lesion development was observed at the 200-µm location when bonding was present on the composite side. In conclusion, the dentin pretreatment with CHX 2% was not able to slow down the development of secondary caries wall lesions in small and wide gaps in this biofilm model.

Minimal Gap Size and Dentin Wall Lesion Development Next to Resin Composite in a Microcosm Biofilm Model

2017 ◽  
Vol 51 (5) ◽  
pp. 475-481 ◽  
Author(s):  
Tamires T. Maske ◽  
Nicolien K. Kuper ◽  
Maximiliano S. Cenci ◽  
Marie-Charlotte D.N.J.M. Huysmans
Keyword(s):  
Resin Composite ◽  
Linear Regression Analysis ◽  
In Vitro Study ◽  
Gap Size ◽  
Lesion Development ◽  
Secondary Caries ◽  
Biofilm Model ◽  
Wall Lesion ◽  
Wall Lesions

This in vitro study investigated the development of dentin wall lesions next to resin composite containing very small gap sizes using an in vitro biofilm model, and evaluated whether a relevant threshold for the gap size could be established. Microcosm biofilms were grown for 14 days within small interfacial gaps between dentin-resin composite discs under intermittent cariogenic challenge. The factor under study was gap size: samples were either restored with composite resin without adhesive procedure (no intentional gap; no bonding [NB] group) or with intentional gaps of 30, 60, or 90 µm, or with complete adhesive procedure (no gap; bonding [B] group). Secondary caries wall lesion progression was measured in lesion depth (LD) and mineral loss (ML) using transversal wavelength independent microradiography at 3 locations: outer surface lesion and wall lesions at 200 and 500 µm distance from gap entrance. Results from linear regression analysis showed that the presence of an intentional gap (30, 60, and 90 µm) affected the secondary caries progression at 200 µm from the gap entrance (p ≤ 0.013). The NB group did not show significant wall lesion development (ML and LD, p ≥ 0.529). At 500 µm distance almost no wall caries development was observed. In conclusion, dentin wall lesions developed in minimal gap sizes, and the threshold for secondary wall lesion development was a gap of around 30 µm in this microcosm biofilm model.

scholarly journals Wall-lesion development in gaps: The role of the adhesive bonding material

2015 ◽  
Vol 43 (8) ◽  
pp. 1007-1012 ◽  
Author(s):  
Anelise F. Montagner ◽  
Nicolien K. Kuper ◽  
Niek J.M. Opdam ◽  
Ewald M. Bronkhorst ◽  
Maximiliano S. Cenci ◽  
...  
Keyword(s):  
Adhesive Bonding ◽  
Lesion Development ◽  
Bonding Material ◽  
Wall Lesion

scholarly journals Gap Size and Wall Lesion Development Next to Composite

2014 ◽  
Vol 93 (7_suppl) ◽  
pp. 108S-113S ◽  
Author(s):  
N.K. Kuper ◽  
N.J.M. Opdam ◽  
J.L. Ruben ◽  
J.J. de Soet ◽  
M.S. Cenci ◽  
...  
Keyword(s):  
Gap Size ◽  
Lesion Development ◽  
Wall Lesion

scholarly journals Histological features of initial secondary caries adjacent to composite resin restorations.

2010 ◽  
Vol 51 (2) ◽  
pp. 15-18
Author(s):  
Berenice Barbachan e Silva ◽  
Débora Heller ◽  
Marisa Maltz
Keyword(s):  
Morphological Analysis ◽  
Polarized Light ◽  
Cavity Wall ◽  
Secondary Caries ◽  
Caries Lesion ◽  
Apical Direction ◽  
Composite Resin Restorations ◽  
Wall Lesion ◽  
Resin Restorations

The aim of this study was to analyse morphologically the initiation of the secondary caries lesion. Thirty-three proximal surfaces adjacent to Class II resin restorations were examined by stereomicroscope (x40) for the presence of caries and gap. Sixty sites (39 sound, 7 with lesions, 14 adjacent to lesions) were prepared for examination using polarized light microscopy in water and after air drying. Lesions were observed in 52.7% of the wet sections and 85.0% of the dried sections. The dried ground sections displayed larger lesions. Further analyses were performed on the dried sections. One hundred per cent of the ground sections from the stereomicroscope carious sites, 87.2% from sound sites, and 71.4% from sites adjacent to lesions displayed demineralized areas. Morphological analysis indicated that caries lesion initiates at the external enamel surface in the interface between tooth and restoration. Two distinct patterns of caries development were observed, related to the direction of enamel rods: (1) the direction of the rods in the adjacent enamel was parallel to the cavity wall (the deepest part of caries penetration was located at the cavity wall), and (2) the direction of the rods ran in the apical direction (the deepest part of caries penetration was oblique to the cavity wall). The pattern 1 could be mistaken for a wall lesion. The prevalence of lesions adjacent to restorations was similar in the sites with (85.7%) and without (84.0%) gaps. The findings support the assumption that secondary caries initiation in vivo is not related to the presence of a gap and follows the direction of the enamel rods.

Caries Diagnosis Within Restored Teeth

1990 ◽  
Vol 4 (1) ◽  
pp. 10-13 ◽  
Author(s):  
E.A.M. Kidd
Keyword(s):  
Common Reason ◽  
Carious Lesion ◽  
Secondary Caries ◽  
Caries Diagnosis ◽  
Diagnostic Difficulties ◽  
Residual Caries ◽  
Wall Lesion

Secondary caries is the most common reason given by dentists for the replacement of restorations, and yet this is a diagnosis that is difficult to make with confidence. This paper attempts to define some of the problems in the diagnosis of caries in restored teeth. The histology of the secondary carious lesion shows that it may be considered in two parts: an outer lesion adjacent to the filling, and a wall lesion which will occur only if there is leakage between the filling and the tooth. The specific diagnostic difficulties addressed are the difficulty of seeing this wall lesion, whether a defective margin indicates secondary caries, and the difficulties of differentiating secondary from residual caries and active from arrested disease. Since further research is needed to solve many of these problems, the paper ends by discussing the consequences of these difficulties for clinicians, epidemiologists, teachers, and research workers.

A threshold gap size for in situ secondary caries lesion development

2019 ◽  
Vol 80 ◽  
pp. 36-40 ◽  
Author(s):  
T.T. Maske ◽  
A.C.C Hollanders ◽  
N.K. Kuper ◽  
E.M. Bronkhorst ◽  
M.S. Cenci ◽  
...  
Keyword(s):  
Gap Size ◽  
Lesion Development ◽  
Secondary Caries ◽  
Caries Lesion

scholarly journals Epithelioid trophoblastic tumor coexisting with choriocarcinoma around an abdominal wall cesarean scar: a case report and review of the literature

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Chunfeng Yang ◽  
Jianqi Li ◽  
Yuanyuan Zhang ◽  
Hanzhen Xiong ◽  
Xiujie Sheng
Keyword(s):  
Abdominal Wall ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Unknown Origin ◽  
Exploratory Laparotomy ◽  
Cesarean Scar ◽  
Trophoblastic Tumor ◽  
Epithelioid Trophoblastic Tumor ◽  
Trophoblastic Tumors ◽  
Wall Lesion

Abstract Background Mixed gestational trophoblastic neoplasms are extremely rare and comprise a group of fetal trophoblastic tumors including choriocarcinomas, epithelioid trophoblastic tumors, and placental site trophoblastic tumors. We present a case of a patient with extrauterine mixed gestational trophoblastic neoplasm adjacent to the abdominal wall cesarean scar. On the basis of a literature review, this type of case has never been reported before due to the unique lesion location and low incidence. Case presentation Our patient was a 39-year-old Chinese woman who had a history of two cesarean sections and one miscarriage. She had a recurrent anterior abdominal wall mass around her cesarean scar, and the mass was initially suspected of being choriocarcinoma of unknown origin. The patient had concomitant negative or mildly increased serum β-human chorionic gonadotropin at follow-up and no abnormal vaginal bleeding or abdominal pain. However, she underwent local excision twice and had two courses of chemotherapy with an etoposide and cisplatin regimen. She finally opted for exploratory laparotomy with abdominal wall lesion removal, subtotal hysterectomy, bilateral salpingectomy, and left ovarian cyst resection, which showed the abdominal wall lesion, whose components were revealed by microscopy and immunohistochemical staining to be approximately 90% epithelioid trophoblastic tumors and 10% choriocarcinomas from a solely extrauterine mixed gestational trophoblastic neoplasm around an abdominal wall cesarean scar. Conclusions It is worth noting whether epithelioid trophoblastic tumor exists in the setting of persistent positive low-level β-human chorionic gonadotropin. More studies are required to provide mechanistic insights into these mixed gestational trophoblastic neoplasms.

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