Predicting Hospital Mortality in Critically Ill Cancer Patients according to Acute Kidney Injury Severity

Oncology ◽  
2011 ◽  
Vol 80 (3-4) ◽  
pp. 160-166 ◽  
Author(s):  
Alexandre Braga Libório ◽  
Krasnalhia Lívia S. Abreu ◽  
Geraldo B. Silva, Jr. ◽  
Rafael S.A. Lima ◽  
Adller G.C. Barreto ◽  
...  
2020 ◽  
Vol 98 (4) ◽  
pp. 932-946 ◽  
Author(s):  
Jihyun Yang ◽  
Chan Johng Kim ◽  
Yoon Sook Go ◽  
Hee Young Lee ◽  
Myung-Gyu Kim ◽  
...  

2012 ◽  
Vol 3 (4) ◽  
pp. 278 ◽  
Author(s):  
Xue-zhong Xing ◽  
Hai-jun Wang ◽  
Chu-lin Huang ◽  
Quan-hui Yang ◽  
Shi-ning Qu ◽  
...  

2016 ◽  
Vol 115 (12) ◽  
pp. 1046-1052 ◽  
Author(s):  
George Kuo ◽  
Shih-Yi Yang ◽  
Shiow-Shuh Chuang ◽  
Pei-Chun Fan ◽  
Chih-Hsiang Chang ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e014171 ◽  
Author(s):  
Peng Li ◽  
Li-ping Qu ◽  
Dong Qi ◽  
Bo Shen ◽  
Yi-mei Wang ◽  
...  

ObjectiveThe purpose of this study was to perform a systematic review and meta-analysis to evaluate the effect of high-dose versus low-dose haemofiltration on the survival of critically ill patients with acute kidney injury (AKI). We hypothesised that high-dose treatments are not associated with a higher risk of mortality.DesignMeta-analysis.SettingRandomised controlled trials and two-arm prospective and retrospective studies were included.ParticipantsCritically ill patients with AKI.InterventionsContinuous renal replacement therapy.Primary and secondary outcome measuresPrimary outcomes: 90-day mortality, intensive care unit (ICU) mortality, hospital mortality; secondary outcomes: length of ICU and hospital stay.ResultEight studies including 2970 patients were included in the analysis. Pooled results showed no significant difference in the 90-mortality rate between patients treated with high-dose or low-dose haemofiltration (pooled OR=0.90, 95% CI 0.73 to 1.11, p=0.32). Findings were similar for ICU (pooled OR=1.12, 95% CI 0.94 to 1.34, p=0.21) and hospital mortality (pooled OR=1.03, 95% CI 0.81 to 1.30, p=0.84). Length of ICU and hospital stay were similar between high-dose and low-dose groups. Pooled results are not overly influenced by any one study, different cut-off points of prescribed dose or different cut-off points of delivered dose. Meta-regression analysis indicated that the results were not affected by the percentage of patients with sepsis or septic shock.ConclusionHigh-dose and low-dose haemofiltration produce similar outcomes with respect to mortality and length of ICU and hospital stay in critically ill patients with AKI.This study was not registered at the time the data were collected and analysed. It has since been registered on 17 February 2017 athttp://www.researchregistry.com/, registration number: reviewregistry211.


Critical Care ◽  
2011 ◽  
Vol 15 (S2) ◽  
Author(s):  
LA Hajjar ◽  
H Palomba ◽  
J Almeida ◽  
J Fukushima ◽  
RE Nakamura ◽  
...  

2015 ◽  
Vol 41 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Nattachai Srisawat ◽  
Florentina E. Sileanu ◽  
Raghavan Murugan ◽  
Rinaldo Bellomo ◽  
Paolo Calzavacca ◽  
...  

Background: Despite standardized definitions of acute kidney injury (AKI), there is wide variation in the reported rates of AKI and hospital mortality for patients with AKI. Variation could be due to actual differences in disease incidence, clinical course, or a function of data ascertainment and application of diagnostic criteria. Using standard criteria may help determine and compare the risk and outcomes of AKI across centers. Methods: In this cohort study of critically ill patients admitted to the intensive care units at six hospitals in four countries, we used KDIGO criteria to define AKI. The main outcomes were the occurrence of AKI and hospital mortality. Results: Of the 15,132 critically ill patients, 32% developed AKI based on serum creatinine criteria. After adjusting for differences in age, sex, and severity of illness, the odds ratio for AKI continued to vary across centers (odds ratio (OR), 2.57-6.04, p < 0.001). The overall, crude hospital mortality of patients with AKI was 27%, which also varied across centers after adjusting for KDIGO stage, differences in age, sex, and severity of illness (OR, 1.13-2.20, p < 0.001). The severity of AKI was associated with incremental mortality risk across centers. Conclusions: In this study, the absolute and severity-adjusted rates of AKI and hospital mortality rates for AKI varied across centers. Future studies should examine whether variation in the risk of AKI among centers is due to differences in clinical practice or process of care or residual confounding due to unmeasured factors.


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