scholarly journals Metabolic Syndrome, Components, and Cardiovascular Disease Prevalence in Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study

2011 ◽  
Vol 33 (6) ◽  
pp. 477-484 ◽  
Author(s):  
Raymond R. Townsend ◽  
Amanda H. Anderson ◽  
Jing Chen ◽  
Crystal A. Gadebegku ◽  
Harold I. Feldman ◽  
...  
2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Emily A Hu ◽  
Cheryl A M Anderson ◽  
Deidra C Crews ◽  
Katherine T Mills ◽  
Jiang He ◽  
...  

ABSTRACT Background Beverages are a source of calories and other bioactive constituents but are an understudied aspect of the diet. Different beverages have varying effects on health outcomes. Objectives We created the Healthy Beverage Score (HBS) to characterize participants’ beverage patterns and examined its association with chronic kidney disease (CKD) progression, incident cardiovascular disease (CVD), and all-cause mortality among individuals with CKD. Methods We conducted a prospective analysis of 2283 adults aged 21–74 y with a baseline estimated glomerular filtration rate of 20–70 mL · min−1 · 1.73 m−2 from the Chronic Renal Insufficiency Cohort. Diet was assessed using a 124-item FFQ at visit 1 (2003–2008). The HBS, ranging from 7 to 28 possible points, consisted of 7 components, each scored from 1 to 4 based on rank distribution by quartile, except alcohol, which was based on sex-specific cutoffs. Participants were given more points for higher consumption of low-fat milk and of coffee/tea, for moderate alcohol, and for lower consumption of 100% fruit juice, whole-fat milk, artificially sweetened beverages, and sugar-sweetened beverages. CKD progression, incident CVD, and mortality were ascertained through January 2018. We conducted multivariable Cox proportional hazards models. Results There were 815 cases of CKD progression, 285 cases of incident CVD, and 725 deaths over a maximum of 14 y of follow-up. Compared with participants in the lowest tertile of the HBS, participants in the highest tertile had a 25% lower likelihood of CKD progression (HR: 0.75; 95% CI: 0.63, 0.89; P-trend = 0.001) and a 17% lower likelihood of all-cause mortality (HR: 0.83; 95% CI: 0.69, 1.00; P-trend = 0.04) after adjusting for sociodemographic, clinical, and dietary factors. There was no significant trend for incident CVD. Conclusions Among individuals with CKD, a healthier beverage pattern was inversely associated with CKD progression and all-cause mortality. Beverage intake may be an important modifiable target in preventing adverse outcomes for individuals with CKD.


2015 ◽  
Vol 116 (10) ◽  
pp. 1527-1533 ◽  
Author(s):  
Juan E. Grunwald ◽  
Maxwell Pistilli ◽  
Gui-Shuang Ying ◽  
Maureen Maguire ◽  
Ebenezer Daniel ◽  
...  

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Emily Hu ◽  
Cheryl A Anderson ◽  
Morgan Grams ◽  
Lawrence J Appel ◽  
Josef Coresh ◽  
...  

Background: The association between an overall healthy beverage pattern and chronic disease outcomes is unknown. We created the Healthy Beverage Score (HBS) to characterize the healthfulness of participants’ beverage profiles and examined its association with chronic kidney disease (CKD) progression, cardiovascular disease (CVD), and all-cause mortality among individuals with CKD. Methods: We conducted a prospective analysis of 2,275 participants aged 21-74 years with an estimated glomerular filtration rate (eGFR) between 20 and 70 mL/min/1.73 m 2 from the Chronic Renal Insufficiency Cohort. Diet was assessed using a 124-item food frequency questionnaire at visit 1 (2003-2008). The HBS (7-28) consisted of 7 components. Each component was scored 1-4 based on rank distribution by quartile. Participants were given more points for higher consumption of low-fat milk, coffee and tea, moderate consumption of alcohol, and lower consumption of 100% fruit juice, full-fat milk, artificially-sweetened beverages, and sugar-sweetened beverages. CKD progression, CVD, and all-cause mortality were ascertained through January 2018. We conducted multivariable Cox proportional hazards models. Results: There were 815 cases of CKD progression, 285 cases of CVD, and 725 deaths over a median of 7, 10, and 12 years of follow-up, respectively. Compared with participants in the lowest tertile of the HBS, participants in the highest tertile had a 27% lower risk of CKD progression (hazard ratio, HR: 0.73, 95% confidence interval, CI: 0.61-0.87) ( P -trend<0.001) and 17% lower risk of all-cause mortality (HR: 0.83, 95% CI: 0.69-1.00) ( P -trend=0.05) after adjusting for covariates ( Table ). There was no significant association for CVD comparing tertile 3 with tertile 1 (HR: 0.93, 95% CI: 0.70-1.23) ( P -trend=0.70). Conclusions: A healthier beverage pattern was associated with lower risk of CKD progression and all-cause mortality. Beverage intake may be an important modifiable dietary target in managing outcomes for individuals with CKD.


2019 ◽  
Vol 25 (6) ◽  
pp. 700-709 ◽  
Author(s):  
Shuangshuang Zhang ◽  
Yong Wang ◽  
Jinsong Cheng ◽  
Ning Huangfu ◽  
Ruochi Zhao ◽  
...  

Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research. In this review, we summarize the recent knowledge about hyperuricemia, with a special focus on its physiology, epidemiology, and correlation with cardiovascular disease. This review also discusses the possible positive effects of treatment to reduce urate levels in patients with cardiovascular disease and hyperuricemia, which may lead to an improved clinical treatment plan.


2015 ◽  
Vol 115 (9) ◽  
pp. 1281-1286 ◽  
Author(s):  
Marie A. Guerraty ◽  
Boyang Chai ◽  
Jesse Y. Hsu ◽  
Akinlolu O. Ojo ◽  
Yanlin Gao ◽  
...  

2010 ◽  
Vol 55 (4) ◽  
pp. B74
Author(s):  
James Lash ◽  
Ana Ricardo ◽  
Matt Budoff ◽  
Claudia Lora ◽  
Martin Keane ◽  
...  

2009 ◽  
Vol 22 (12) ◽  
pp. 1235-1241 ◽  
Author(s):  
S. S. DeLoach ◽  
L. J. Appel ◽  
J. Chen ◽  
M. M. Joffe ◽  
C. A. Gadegbeku ◽  
...  

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