Fine Needle Aspiration Cytology of a Metastatic Ductal Carcinoma of the Prostate

2006 ◽  
Vol 50 (4) ◽  
pp. 469-472 ◽  
Author(s):  
David Alrahwan ◽  
Gregg Staerkel ◽  
Yun Gong
1989 ◽  
Vol 5 (4) ◽  
pp. 371-377 ◽  
Author(s):  
Nour Sneige ◽  
Virginia A. White ◽  
Ruth L. Katz ◽  
Patricia Troncoso ◽  
Herman I. Libshitz ◽  
...  

2012 ◽  
Vol 2 (4) ◽  
pp. 285-288
Author(s):  
RC Adhikari ◽  
A Jha

Background: Pure mucinous carcinoma is a rare histologic type of mammary neoplasm and may exist as mixed mucinous-ductal carcinoma. This study aims to describe fine needle aspiration cytology features of mucinous carcinoma of breast diagnosed in Tribhuvan University Teaching Hospital, Nepal over the period of 2 years and to correlate with histological findings.Materials and Methods: There were a total of 8 cases of mucinous carcinoma of breast, diagnosed on fine needle aspiration cytology in TUTH during the period from April 2010 to March 2012. The patient’s age, laterality of involvement, fine needle aspiration cytology features, gross and histological findings, type of surgery performed and tumor size were evaluated. Fine needle aspiration cytology smears were evaluated for cellularity, amount of mucin, chicken-wire vasculature and nuclear atypia.Results: Fine needle aspiration cytology provided a pre-operative diagnosis of mucinous carcinoma in 5 cases and mixed mucinous carcinoma-invasive ductal carcinoma in 3 cases. Histological examination showed pure mucinous carcinoma in 3 cases, mixed mucinous carcinoma-invasive ductal carcinoma in 4 cases and mixed cribriform carcinoma and ductal carcinoma in 1 case.Conclusion: Mucinous carcinoma may appear clinically and radiologically benign and fine needle aspiration cytology plays important role in the correct pre-operative diagnosis. Significant nuclear pleomorphism and necrosis, in addition to extracellular mucin suggests mixed mucinous carcinomainvasive ductal carcinoma.Journal of Pathology of Nepal (2012) Vol. 2, 285-288DOI: http://dx.doi.org/10.3126/jpn.v2i4.6879


2014 ◽  
Vol 2 (2) ◽  
pp. 40-43 ◽  
Author(s):  
Adnan Khan ◽  
Raza Jamali ◽  
Muneeb Jan ◽  
Maria Tasneem

Background: A large number of patients have been suffer from breast cancer worldwide and this trend is increasing. It is difficult to determine whether a lump is benign or malignant from clinical assessment; thus, the need for micropic and tissue analysis arises. Methods: This comparative retrospective cross sectional study was conducted in the Department of Pathology, Rehman Medical Institute, Peshawar, Pakistan from January 2006 to March 2013, to determine the value of fine needle aspiration cytology (FNAC) in the diagnosis of breast lump and to compare the result of FNAC with histological diagnosis to assess its accuracy. Results: Seventy-four  cases with breast lumps were presented for FNAC. Of these, 32.4% were reported as a C2 lesion, 4.1% were reported as benign with atypical cells (C3), 8.1% cases were suspicious for malignancy (C4), and 55.4% were positive for malignancy (C5). On histopathology examination, out of 24 cases which were reported as C2 lesions, 95.8% were benign and 4.1% turned out to be invasive ductal carcinoma. Of the cases that presented as C3 lesions, one was diagnosed as benign duct ectasia, one with ductal carcinoma in situ, and one with invasive ductal carcinoma on histopathological examination. The cases that were diagnosed as C4 lesions all turned out to be carcinoma on histopathology.  In this study, FNAC and histopathology diagnoses were strongly correlated [r 0.92, p <0.001]. Conclusion: Diagnosis of breast lump based on FNAC should be practiced as there is high correlation with histopathological finding. FNAC should be used as a routine diagnostic procedure due to its cost effectiveness, thus maximizing the availability of effective health care to patients with breast lesions.


2017 ◽  
Vol 4 (4) ◽  
pp. 1171
Author(s):  
Rajat Gupta ◽  
Deepika Dewan ◽  
Dinesh Kumar ◽  
Rameshwar Sharma

Background: Fine-needle aspiration cytology (FNAC) has proved to be a rapid, safe, cost effective and good screening or initial diagnostic tool for early diagnosis and management of palpable breast swellings. The present study was conducted to describe and categorize various breast lesions on FNAC. The study also aimed to find out the diagnostic accuracy of FNAC procedure.Methods: This study was carried out on 175 patients who presented with palpable breast swellings in Government Hospital Gandhi Nagar, Jammu, Jammu and Kashmir, India and subsequently referred to Pathology Department of Govt. Hospital Gandhi Nagar over a period of two years and eight months from January 2013 to September 2015. Lesions were categorized as per cytomorphological features obtained on FNAC. Histopathological correlation was done on 68 cases inclusive of all malignant cases.Results: 156 (89%) cases were categorized as benign and 19 cases (11%) as malignant on FNAC out of 175 cases. The most common benign lesion was fibro adenoma (41%) and the most common breast carcinoma was ductal carcinoma (65%). Sensitivity, specificity, positive predictive value, negative predictive value, LR+ and LR-  came out to be 85%, 95.8%, 89%, 93.8%, 20.4 and 0.15 respectively.Conclusions: FNAC is a good screening procedure for initial diagnosis of breast lumps. It is highly useful procedure in secondary care centres due to its cost effectiveness, rapid and safe nature.


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