Fine Needle Aspiration Cytology and Flow Cytometry in the Diagnosis and Subclassification of Non-Hodgkin’s Lymphoma Based on the World Health Organization Classification

2007 ◽  
Vol 51 (3) ◽  
pp. 390-398 ◽  
Author(s):  
Markus Bangerter ◽  
Olaf Brudler ◽  
Bernhard Heinrich ◽  
Martin Griesshammer
Keyword(s):  
Flow Cytometry ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
World Health ◽  
World Health Organization Classification ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
The World ◽  
Needle Aspiration Cytology ◽  
Health Organization

scholarly journals Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis

Rare Tumors ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 172-174 ◽  
Author(s):  
Rehab M. Samaka ◽  
Mona A. Kandil
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Soft Tissues ◽  
Pelvic Mass ◽  
Needle Aspiration ◽  
World Health ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Health Organization

Parachordoma is an extremely rare soft tissue tumor of unknown lineage. Parachordoma develops most often on the extremities. Only 2 cases have been reported as pelvic parachordoma. A 46-year old Egyptian woman with a huge painful pelvic mass was found to have a parachordoma with ectopic pelvic right kidney. There is only one report in the literature of fine needle aspiration cytology in this setting. The microscopic picture of parachordoma is not new to pathologists but the gross picture of this rare tumor has not previously been published; not even in the World Health Organization classification of soft tissues tumors. Diagnosis was confirmed by immunohistochemistry. The patient is in good clinical condition without any evidence of recurrence or metastasis after 84 months of follow up.

Investigation of lymphoid lesions of the head and neck using combined fine needle aspiration cytology and flow cytometry: Accuracy and pitfalls

Cytopathology ◽  
2019 ◽  
Vol 30 (4) ◽  
pp. 370-377 ◽  
Author(s):  
Heinrich Crous ◽  
Amanda Gillam ◽  
Mary‐Anne Kalokerinos ◽  
Sasenka Knezevic ◽  
Peter Hobson ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Head And Neck ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Systematic Review of the Effectiveness of Fine-Needle Aspiration and/or Core Needle Biopsy for Subclassifying Lymphoma

2015 ◽  
Vol 139 (2) ◽  
pp. 245-251 ◽  
Author(s):  
John K. Frederiksen ◽  
Meenal Sharma ◽  
Carla Casulo ◽  
W. Richard Burack
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Diagnostic Yield ◽  
Needle Aspiration ◽  
Lymph Node Biopsy ◽  
World Health ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Context The World Health Organization system for lymphoma classification relies on histologic findings from excisional biopsies. In contradistinction to expert guidelines, practitioners increasingly rely on fine-needle aspiration cytology and core needle biopsies rather than excisional biopsies to diagnose lymphomas. Objective To determine a rate at which fine-needle aspiration cytology and core needle biopsies, combined with flow cytometry and/or genetic techniques, can provide a diagnosis sufficient for optimal medical management of lymphoma. Data Sources The English-language literature on fine-needle aspiration cytology and core needle biopsies for lymphoma was reviewed to identify studies that provided interpretations of all specimens regardless of whether these were deemed diagnostic. Conclusions Forty-two studies (1989–2012) specified the lymphoma subtypes for each diagnosis or indicated a rate at which the methods failed to provide a diagnosis. The median rate at which fine-needle aspiration cytology and core needle biopsies yielded a subtype-specific diagnosis of lymphoma was 74%. Strictly adhering to expert guidelines, which state that follicular lymphoma cannot be graded by these techniques, decreased the diagnostic yield further to 66%. Thus, 25% to 35% of fine-needle aspirates and/or core biopsies of nodes must be followed by an excisional lymph node biopsy to fully classify lymphoma.

scholarly journals Gallbladder carcinoma: An attempt of WHO histological classification on fine needle aspiration material

CytoJournal ◽  
2013 ◽  
Vol 10 ◽  
pp. 12 ◽  
Author(s):  
Rajni Yadav ◽  
Deepali Jain ◽  
Sandeep R. Mathur ◽  
Atul Sharma ◽  
Venkateswaran K. Iyer
Keyword(s):  
Fine Needle Aspiration ◽  
Who Classification ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Undifferentiated Carcinoma ◽  
World Health ◽  
Fine Needle ◽  
Signet Ring ◽  
Needle Aspiration Cytology ◽  
Health Organization

Background: Carcinoma of the gallbladder (CaGB) is common in India and its prognosis depends primarily on the extent of the disease and histological type. We aim to study the role of guided fine needle aspiration cytology (FNAC) for diagnosis of CaGB and to evaluate the feasibility of applying world health organization (WHO) classification on fine needle aspiration (FNA) material to predict the outcome of the tumor. Materials and Methods: Retrospective cytomorphologic analysis was performed in all cases of CaGB diagnosed by ultrasound (US) guided FNAC over a period of 2 years. A specific subtype was assigned according to WHO classification based on characteristic cytologic features. These included papillary or acinar arrangement, intra and extracellular mucin, keratin, rosettes and columnar, signet ring, atypical squamous, small, clear, spindle and giant cells. Correlation with histopathology was performed when available. Results: A total of 541 aspirations with clinical or radiological suspicion of primary CaGB were studied. Of these, 54 aspirates were unsatisfactory. Fifty cases were negative for malignancy. Remaining 437 aspirates were positive for carcinoma. Histopathologic diagnosis was available in 32 cases. Adenocarcinoma was the most frequent diagnosis in 86.7% of cases. Mucinous, signet ring, adenosquamous, squamous, small cell, mixed adenoneuroendocrine and undifferentiated carcinoma including spindle and giant cell subtypes were diagnosed identifying specific features on FNAC. Correlation with histopathology was present in all, but one case giving rise to sensitivity of 96.8%. No post-FNA complications were recorded. Conclusions: US guided FNAC is a safe and effective method to diagnose CaGB. Although, rare, clinically and prognostically significant variants described in WHO classification can be detected on cytology.

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