Preoperative Cytodiagnosis of Cystic Pleomorphic Adenoma with Squamous Metaplasia and Cholesterol Crystals

2009 ◽  
Vol 53 (1) ◽  
pp. 101-104 ◽  
Author(s):  
Neelaiah Siddaraju ◽  
Paari Murugan ◽  
Debdatta Basu ◽  
Surendra Kumar Verma
Keyword(s):  
Pleomorphic Adenoma ◽  
Squamous Metaplasia ◽  
Cholesterol Crystals

scholarly journals Pleomorphic adenoma with squamous and appendageal metaplasia mimicking mucoepidermoid carcinoma on cytology

CytoJournal ◽  
2008 ◽  
Vol 6 ◽  
pp. 5 ◽  
Author(s):  
Meenakshi Batrani ◽  
Manju Kaushal ◽  
A. K. Sen ◽  
Rajbala Yadav ◽  
N. K. Chaturvedi
Keyword(s):  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Squamous Metaplasia ◽  
Salivary Gland Tumor ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Case Presentation ◽  
Squamous Cells ◽  
Foreign Body Giant Cells ◽  
Needle Aspiration Cytology

Background: Histological diversity is the hallmark of pleomorphic adenoma, the most common salivary gland tumor. It may cause difficulty in cytological interpretation, due to limited and selective sampling. Case presentation: A 16-year-old female patient presented with right cheek swelling. Fine needle aspiration cytology showed squamous cells, basaloid cells, and foamy cells, along with extracellular keratin and foreign body giant cells. Characteristic metachromatic fibrillary chondromyxoid stroma, which is usually seen in pleomorphic adenoma, was not seen in the aspirate. A diagnosis of mucoepidermoid carcinoma was given on cytology. Subsequent resection revealed an encapsulated pleomorphic adenoma, with extensive squamous metaplasia and appendageal differentiation on histology. Conclusion: This case illustrates that pleomorphic adenoma with squamous metaplasia presents a potential for misinterpretation as mucoepidermoid carcinoma on cytology. We discuss the various pitfalls and the features that are helpful in distinguishing these two lesions.

scholarly journals Cystic and florid squamous metaplasia in pleomorphic adenoma of palate – A diagnostic dilemma

2014 ◽  
Vol 5 (4) ◽  
pp. 108-110 ◽  
Author(s):  
H Kaveri ◽  
K Gopalkrishnana ◽  
Anehosur Venkatesh
Keyword(s):  
Pleomorphic Adenoma ◽  
Myoepithelial Cell ◽  
Benign Tumor ◽  
Squamous Metaplasia ◽  
Myoepithelial Cells ◽  
Cystic Degeneration ◽  
Minor Trauma ◽  
Medical Sciences ◽  
Diagnostic Dilemma

Pleomorphic adenoma is a benign tumor of salivary gland. Controversy regarding the origin of various mesenchymal components exists and myoepithelial cell has a key role. Metaplastic process is triggered by minor trauma and probable etiology for this change is ischemia. It is diagnostically challenging, because diagnostic pit falls in the presence of mucinous and squamous metaplasia. Report a case of pleomorphic adenoma in the palate of a 35 years old Indian female. Biopsy revealed epithelial component with extensive squamous metaplasia and cystic degeneration. Here we discuss the role of myoepithelial cells in the pathogenesis of pleomorphic adenoma and diagnostic pit falls. DOI: http://dx.doi.org/10.3126/ajms.v5i4.10434 Asian Journal of Medical Sciences 2014 Vol.5(4); 108-110

scholarly journals Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma

2018 ◽  
Vol 52 (6) ◽  
pp. 411-415 ◽  
Author(s):  
Swati Sharma ◽  
Monica Mehendiratta ◽  
Nivedita Chaudhary ◽  
Vineet Gupta ◽  
Maulshree Kohli ◽  
...  
Keyword(s):  
Pleomorphic Adenoma ◽  
Squamous Metaplasia

scholarly journals A challenging case of squamous metaplasia in a pleomorphic adenoma: diagnostic and clinical pitfalls

2015 ◽  
Vol 2015 (9) ◽  
pp. rjv113 ◽  
Author(s):  
Simon Brisebois ◽  
Myrna Chababi Atallah ◽  
Martin Borduas ◽  
Pierre-Hugues Fortier
Keyword(s):  
Pleomorphic Adenoma ◽  
Squamous Metaplasia

scholarly journals Pleomorphic adenoma of soft palate with extensive squamous metaplasia – A diagnostic enigma

2019 ◽  
Vol 8 (4) ◽  
pp. 268
Author(s):  
Rashmi Patnayak ◽  
Sandip Mohanty ◽  
AnjanKumar Sahoo ◽  
AdyaKinkara Panda ◽  
Amitabh Jena
Keyword(s):  
Pleomorphic Adenoma ◽  
Soft Palate ◽  
Squamous Metaplasia

scholarly journals Transmucosal Fine Needle Aspiration of Oral and Pharyngeal Lesions

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Fang-Ming Deng ◽  
Jack Hsu ◽  
Kamal K. Khurana
Keyword(s):  
Pleomorphic Adenoma ◽  
Fine Needle Aspiration ◽  
Squamous Metaplasia ◽  
Needle Aspiration ◽  
Histological Diagnosis ◽  
First Line ◽  
Cytologic Diagnosis ◽  
Fine Needle ◽  
Sensitivity Specificity ◽  
Malignant Diagnosis

Fine Needle aspiration (FNA) studies of oropharyngeal lesions are few and limited. We retrospectively reviewed cytologic diagnosis and cytohistologic correlation of 28 cases of FNAs of oropharyngeal lesions. Cytologically, 11 cases were diagnosed as malignant/suspicious and 17 cases as benign. Ten of these cases diagnosed as malignant/suspicious correlated with the subsequent histological diagnosis or were compatible with previous histological diagnoses. One case categorized as suspicious for malignancy revealed pleomorphic adenoma with extensive squamous metaplasia. Of the 17 cases diagnosed as benign by cytology, 11 correlated with the subsequent histological diagnosis. The remaining 6 cytologically benign cases were considered clinically benign, and there was no histological followup. Clinical followup on these 6 patients did not reveal any evidence of disease. The sensitivity, specificity, and accuracy of malignant diagnosis were 100%, 95%, and 97%. FNA biopsy may be used as the first line of investigation in evaluation of oropharyngeal lesions.

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