Clinical Efficacy and Safety in Children with Vesicoureteral Reflux of a Single Injection of Two Different Bulking Agents – Polydimethylsiloxane (Macroplastique) or Dextranomer/Hyaluronic Acid Copolymer (Deflux): A Short-Term Prospective Comparative Study

2011 ◽  
Vol 87 (3) ◽  
pp. 299-303 ◽  
Author(s):  
Sun-Ouck Kim ◽  
Bo Sung Shin ◽  
In Sang Hwang ◽  
Eu Chang Hwang ◽  
Kyung Jin Oh ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Comparative Study ◽  
Vesicoureteral Reflux ◽  
Clinical Efficacy ◽  
Single Injection ◽  
Bulking Agents ◽  
Efficacy And Safety ◽  
Short Term ◽  
Acid Copolymer ◽  
Prospective Comparative Study

scholarly journals Endoscopic Treatment of Vesicoureteral Reflux in Children with Dextranomer/Hyaluronic Acid—A Single Surgeon's 6-Year Experience

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Hou-Chuan Chen ◽  
Chou-Ming Yeh ◽  
Chia-Man Chou
Keyword(s):  
Hyaluronic Acid ◽  
Antibiotic Prophylaxis ◽  
Vesicoureteral Reflux ◽  
Ureteral Obstruction ◽  
Endoscopic Treatment ◽  
Single Injection ◽  
Ureteral Reimplantation ◽  
Cure Rate ◽  
Acid Copolymer

Endoscopic treatment for vesicoureteral reflux (VUR) has become an established alternative to long-term antibiotic prophylaxis and ureteral reimplantation. We present the outcome of endoscopic treatment with dextranomer/hyaluronic acid copolymer (Deflux) for VUR in children by a single surgeon at our institute from October 2003 to October 2009. We reviewed the cases of 150 patients (total 239 ureters), 56 girls (37%) and 94 boys (63%), with a mean age of 2.2 years and a median followup of 2.5 years (range 3–68 months). Among the 239 ureters treated, 67.4% (161/239) were cured with a single injection, and a second and third injection raised the cure rate to 86.6% (207/239) and 88.3% (211/239), respectively. None had postoperative ureteral obstruction.

scholarly journals Efficacy and Safety of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild-to-Moderate Acne Vulgaris: A Comparative Study

2021 ◽  
pp. 2021063
Author(s):  
Surabhi Dayal ◽  
Satbir Singh ◽  
Priyadarshini Sahu
Keyword(s):  
Salicylic Acid ◽  
Adverse Effects ◽  
Comparative Study ◽  
Clinical Efficacy ◽  
Trichloroacetic Acid ◽  
Acne Vulgaris ◽  
Efficacy And Safety ◽  
Inflammatory Lesions ◽  
Treatment Groups ◽  
Proven Efficacy

Background: Both salicylic acid (SA) and trichloroacetic acid (TCA) have proven efficacy with goodsafety profiles in the treatment of acne vulgaris. Objectives: This study compared the clinical efficacy and safety of 25% TCA and 30% SA peels in thetreatment of mild and moderate acne vulgaris. Methods: Patients with mild or moderate acne vulgaris were randomized into 2 groups of 25 personseach, and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Evaluationof active acne was done by individual lesion counts (comedones, papules and pustules) and calculationof the Michaelsson acne score (MAS). Results: Both peels led to significant decrease in individual lesion counts and MAS compared to baselinevalues, without significant differences between the treatment groups. Thus, the peels had equivalentefficacy against acne vulgaris. The TCA peel was better in treating non-inflammatory lesions,while the SA peel was better for inflammatory lesions, but the differences were not significant. Noserious adverse effects were recorded, but more patients in the TCA peel group experienced burningand stinging sensations. Conclusion: The efficacy of 25% TCA is comparable to that of 30% SA in mild-to-moderate acnevulgaris, but safety and tolerability were better with the SA peel than TCA peel.

Endoscopic Injection of Dextranomer/Hyaluronic Acid Copolymer to Correct Vesicoureteral Reflux Following Failed Ureteroneocystostomy

2006 ◽  
Vol 176 (4S) ◽  
pp. 1861-1863 ◽  
Author(s):  
David Kitchens ◽  
Eugene Minevich ◽  
William DeFoor ◽  
Pramod Reddy ◽  
Jeffrey Wacksman ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Vesicoureteral Reflux ◽  
Endoscopic Injection ◽  
Acid Copolymer
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