The Significance of the External Limiting Membrane in the Recovery of Photoreceptor Layer after Successful Macular Hole Closure: A Study by Spectral Domain Optical Coherence Tomography

2011 ◽  
Vol 225 (3) ◽  
pp. 176-184 ◽  
Author(s):  
Panagiotis G. Theodossiadis ◽  
Vlassis G. Grigoropoulos ◽  
George P. Theodossiadis
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Spectral Domain ◽  
Optical Coherence ◽  
External Limiting Membrane ◽  
Photoreceptor Layer ◽  
Hole Closure

scholarly journals Predicting macular hole closure with ocriplasmin based on spectral domain optical coherence tomography

Eye ◽  
2016 ◽  
Vol 30 (5) ◽  
pp. 740-745 ◽  
Author(s):  
D H W Steel ◽  
C Parkes ◽  
V T Papastavrou ◽  
P J Avery ◽  
I A El-Ghrably ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Hole Closure

Early Imaging of Macular Hole Closure: A Diagnostic Technique and Its Quality for Gas-Filled Eyes with Spectral Domain Optical Coherence Tomography

2013 ◽  
Vol 229 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Toshifumi Yamashita ◽  
Takehiro Yamashita ◽  
Hiroki Kawano ◽  
Yasushi Sonoda ◽  
Keita Yamakiri ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Diagnostic Technique ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Early Imaging ◽  
Hole Closure

scholarly journals External limiting membrane: retinal structural barrier in diabetic macular edema

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sandeep Saxena ◽  
Levent Akduman ◽  
Carsten H. Meyer
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Barrier Effect ◽  
External Limiting Membrane ◽  
Ellipsoid Zone ◽  
Structural Barrier ◽  
Sd Oct

AbstractAdvances in spectral-domain optical coherence tomography (SD-OCT) technology have enhanced the understanding of external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema. An increase in VEGF has been demonstrated to be associated with sequential ELM and EZ disruption on SD-OCT. An intact ELM is a prerequisite for an intact EZ in DME. Anti-VEGF therapy leads to restoration of barrier effect of ELM. The ELM restores first followed by EZ restoration.

Vitreomacular interface alterations following peripheral laser retinopexy: Interface changes after laser

2019 ◽  
Vol 30 (5) ◽  
pp. 941-947
Author(s):  
Gian Marco Tosi ◽  
Tommaso Bacci ◽  
Antonio Tarantello ◽  
Davide Marigliani ◽  
Giacomo Calmanti ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Pars Plana Vitrectomy ◽  
Control Analysis ◽  
Optical Coherence ◽  
Vitreomacular Adhesion ◽  
Mean Width ◽  
Pars Plana ◽  
Laser Group ◽  
Hole Closure

Aim: To demonstrate the morphological outcomes of macular hole following prophylactic peripheral laser retinopexy (PPLR). Methods: Our retrospective case-control analysis included 92 eyes, 55 in the laser group and 37 in the non-laser group. Fifty-five patients were subjected to prophylactic peripheral laser retinopexy in preparation for pars plana vitrectomy for macular hole, with and without vitreomacular adhesion (laser group). Before and after prophylactic peripheral laser retinopexy, we evaluated any changes in vitreomacular anatomy by optical coherence tomography. Optical coherence tomography changes were also analyzed in the visits preceding pars plana vitrectomy in 37 macular hole eyes not subjected to prophylactic peripheral laser retinopexy (non-laser group). Results: In the laser group, 7 out of 55 eyes (12.7%) showed macular hole closure (6 out of 18 macular hole eyes with vitreomacular adhesion (33.3%) and 1 out of 37 eyes without vitreomacular adhesion (2.7%)), while no patients showed macular hole closure in the non-laser group (p < 0.05). The mean width of the seven closed macular hole was 191.4 µm (range: 59–282 µm). In all except one of the six macular hole eyes with vitreomacular adhesion, the macular hole closed without vitreomacular adhesion release. In our analysis of the patient subgroup with vitreomacular adhesion, we observed a release of vitreomacular adhesion in 3 out of 18 eyes (16.6%) in the laser group and in 1 out of 13 eyes (7.6%) in the non-laser group (p > 0.05). Conclusion: These findings support a possible beneficial role for prophylactic peripheral laser retinopexy in selected individuals with macular hole.

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