scholarly journals Assessment of Lower Limb Microcirculation: Exploring the Reproducibility and Clinical Application of Laser Doppler Techniques

2011 ◽  
Vol 24 (3) ◽  
pp. 136-143 ◽  
Author(s):  
M. Klonizakis ◽  
G. Manning ◽  
R. Donnelly
Keyword(s):  
Clinical Application ◽  
Lower Limb ◽  
Laser Doppler ◽  
Doppler Techniques

scholarly journals Limb perfusion in the lower limb amputee—a comparative study using a laser Doppler flowmeter and a transcutaneous oxygen electrode

1987 ◽  
Vol 11 (2) ◽  
pp. 80-84 ◽  
Author(s):  
S. L. E. Fairs ◽  
R. O. Ham ◽  
B. A. Conway ◽  
V. C. Roberts
Keyword(s):  
Laser Doppler Flowmetry ◽  
Lower Limb ◽  
Local Heating ◽  
Objective Assessment ◽  
Relative Increase ◽  
Laser Doppler ◽  
Transcutaneous Oxygen ◽  
Doppler Flowmetry ◽  
Amputation Level ◽  
Significant Difference

Accurate and objective assessment of amputation level in the lower limb plays an important role in patient management. Laser Doppler flowmetry (LDF) is a new and noninvasive technique for skin blood flow measurement and has been used pre-operatively in 25 patients undergoing amputation for vascular disease and in five normal controls. Baseline flux measurements were made at room temperature on the medial aspect of legs and then again after local heating of the skin for five minutes. Transcutaneous oxygen measurements were made at the same site for comparison and amputation level in patients selected on this basis. Significant differences (p<0.001) in TcPO2 values were found between controls (10.9±0.5kPa), below-knee (BK) amputees (6.0±1.5kPa) and above-knee (AK) amputees (1.5±0.6kPa). Baseline LDF flux did not differ significantly between any group. Heated flux values did however show a significant difference (p<0.005) between controls (52.4±23.5) and both BK (20.6±9.2) and AK groups (8.1±7.7) and also between the amputee groups. The relative increase in flux (heated flux/baseline flux) differed significantly between the BK (3.3±1.5) and AK (1.2±0.3) groups (p<0.001) and between these two and the controls (11.2±5.4) (p<0.001). The correlation between relative increase in flux and TcPO2 was 0.7 (p<0.001). It is concluded that laser Doppler flowmetry used in conjunction with thermal stressing could provide a quick, simple and non-invasive method for objectively determining amputation level in the lower limb.

Reflex control of the cutaneous circulation during passive body core heating in humans

2000 ◽  
Vol 88 (5) ◽  
pp. 1756-1764 ◽  
Author(s):  
Jochen K. Peters ◽  
Takeshi Nishiyasu ◽  
Gary W. Mack
Keyword(s):  
Blood Pressure ◽  
Heat Stress ◽  
Lower Body Negative Pressure ◽  
Venous Pressure ◽  
Laser Doppler ◽  
Vascular Conductance ◽  
Arterial Blood ◽  
Body Core ◽  
Doppler Techniques ◽  
The Impact

The impact of body core heating on the interaction between the cutaneous and central circulation during blood pressure challenges was examined in eight adults. Subjects were exposed to −10 to −90 mmHg lower body negative pressure (LBNP) in thermoneutral conditions and −10 to −60 mmHg LBNP during heat stress. We measured forearm vascular conductance (FVC; ml ⋅ min−1 ⋅ 100 ml−1 ⋅ mmHg−1) by plethysmography; cutaneous vascular conductance (CVC) by laser-Doppler techniques; and central venous pressure, arterial blood pressure, and cardiac output by impedance cardiography. Heat stress increased FVC from 5.7 ± 0.9 to 18.8 ± 1.3 conductance units (CU) and CVC from 0.21 ± 0.07 to 1.02 ± 0.20 CU. The FVC-CVP relationship was linear over the entire range of LBNP and was shifted upward during heat stress with a slope increase from 0.46 ± 0.10 to 1.57 ± 0.3 CU/mmHg CVP ( P < 0.05). Resting CVP was lower during heat stress (6.3 ± 0.6 vs. 7.7 ± 0.6 mmHg; P < 0.05) but fell to similar levels during LBNP as in normothermic conditions. Data analysis indicates an increased capacity, but not sensitivity, of peripheral baroreflex responses during heat stress. Laser-Doppler techniques detected thermoregulatory responses in the skin, but no significant change in CVC occurred during mild-to-moderate LBNP. Interestingly, very high levels of LBNP produced cutaneous vasodilation in some subjects.

Physical sciences

2020 ◽  
Vol 44 (6) ◽  
pp. 373-383
Author(s):  
Phillip M Stevens
Keyword(s):  
Clinical Application ◽  
Upper Limb ◽  
Lower Limb ◽  
Material Science ◽  
Load Distribution ◽  
Educational Needs ◽  
Physical Sciences ◽  
Material Sciences ◽  
To Come ◽  
Original Edition

In the original edition of Prosthetics and Orthotics International, Dr Sidney Fishman identified what he anticipated as foundational educational needs for the emerging field of clinical prosthetics and orthotics. Within the broader construct of the physical sciences, this included mathematics, physics, chemistry, biomechanics, and material sciences. The clinical application of these disciplines to expanding the collective understanding within the field is described, including the biomechanics of able-bodied and prosthetic gait, the material science of socket construction, the physics of suspension and load distribution, and the engineering of prosthetic components to mimic human biomechanics. Additional applications of the physical sciences to upper limb prosthetics and lower limb orthotics are also described. In contemplating the continued growth and maturation of the field in the years to come, mechatronics and statistics are suggested as future areas where clinical proficiency will be required.

Vascular Assessment in Patients With a Lower Limb Wound: A Correlational Study of Photoplethysmography and Laser Doppler Flowmetry Toe Pressure Techniques

2020 ◽  
pp. 193229682097997
Author(s):  
Jérôme Patry ◽  
Louis Laurencelle ◽  
Justine Bélisle ◽  
Maryse Beaumier
Keyword(s):  
Laser Doppler Flowmetry ◽  
Pressure Measurement ◽  
Lower Limb ◽  
Laser Doppler ◽  
Lower Limbs ◽  
Correlational Study ◽  
Care Clinic ◽  
Doppler Flowmetry ◽  
Vascular Assessment ◽  
Toe Pressure

Background: Vascular assessment of the lower limbs is essential in patients with diabetes. In the presence of noncompressible arteries, the ankle brachial index (ABI) can either be inconclusive or provide false-positive results. Toe pressure measurement has been suggested as an alternative as a noninvasive method for detecting peripheral arterial disease (PAD). Toe pressure measurement can be performed either by photoplethysmography (PPG) or by Laser Doppler flowmetry (LDF). The aim of this study was to determine correlations between the two techniques in order to promote the use of PPG in clinical practice. Methods: This was a prospective correlational study of 108 consecutive recruited adult patients, with and without diabetes, with at least one lower limb wound from a University-affiliated hospital wound care clinic. Toe pressure measurements were both performed with PPG and LDF devices. Results: Mean toe pressure values for PPG and LDF were, respectively, 83.7 (SD 35.4) and 79.5 (SD 32.0) mmHg (with a paired t-test 3.969, P < 0.01). In patients with at least one lower limb wound, a strong linear relation was found between PPG and LDF toe pressure techniques with a Pearson’s r correlation coefficient of 0.920 ( P < 0.001). Conclusions: PPG and LDF toe pressure techniques are equivalent in patients with at least one lower limb wound, irrespective of the presence of diabetes. Therefore, in the presence of an ABI with inconclusive results, such as in a patient with noncompressible vessels, both toe pressure techniques can be used for assessing the vascular supply of the lower limb with a wound.

Cadaveric study and clinical application of turnover fascial flap for lower-limb defects

2010 ◽  
Vol 34 (5) ◽  
pp. 387-394
Author(s):  
Visweswar Bhattacharya ◽  
Partha Sarathi Barooah ◽  
Saurabh Rawat ◽  
Gaurab Ranjan Chaudhuri ◽  
Neeraj Kant Agrawal ◽  
...  
Keyword(s):  
Clinical Application ◽  
Lower Limb ◽  
Cadaveric Study ◽  
Limb Defects ◽  
Fascial Flap

SCANNING LASER DOPPLER TECHNIQUES FOR VIBRATION TESTING

2008 ◽  
Vol 16 (6) ◽  
pp. 21-26 ◽  
Author(s):  
P. Sriram ◽  
J. I. Craig ◽  
S. Hanagud
Keyword(s):  
Laser Doppler ◽  
Scanning Laser ◽  
Vibration Testing ◽  
Doppler Techniques
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