Helical Tomotherapy: Image-Guided and Adaptive Radiotherapy

2011 ◽  
pp. 165-180 ◽  
Author(s):  
Patrick Kupelian ◽  
Katja Langen
Keyword(s):  
Helical Tomotherapy ◽  
Adaptive Radiotherapy ◽  
Image Guided

Bladder preservation with helical tomotherapy-based, image-guided radiotherapy: A clinical study using “plan of the day” adaptive radiotherapy.

2011 ◽  
Vol 29 (7_suppl) ◽  
pp. 289-289
Author(s):  
V. Murthy
Keyword(s):  
Clinical Study ◽  
Helical Tomotherapy ◽  
Bladder Wall ◽  
Transitional Cell ◽  
Adaptive Radiotherapy ◽  
Post Treatment ◽  
Bladder Preservation ◽  
Trimodality Therapy ◽  
Image Guided Radiotherapy ◽  
Image Guided

289 Background: This clinical study assessed the potential of helical tomotherapy-based, image-guided radiotherapy (IGRT) to increase the accuracy of bladder irradiation using a plan of the day adaptive radiotherapy (ART) technique. Methods: Ten patients with stage T2b-T4- N0 M0, histologically proven bladder transitional cell carcinoma, who underwent bladder preservation with trimodality therapy in an ongoing trial, are reported. All patients received a dose of 64Gy/32# to the whole bladder. Seven of these also received a simultaneous integrated boost of 68Gy/32 fractions to tumor bed. The ART technique entailed the generation of six planning PTVs and thus six separate IMRT plans for each patient. All patients underwent daily pre and post treatment MVCT imaging to correct for positioning errors, choose the plan of the day, depending on deformation of the bladder, and verify intrafraction filling at the end of treatment. Margins needed to encompass the bladder wall in each direction during radiotherapy was determined in the following three scenarios: (a) centers with availability of daily IGRT and performing ART, (b) centers with IGRT not doing ART, and (c) centers without IGRT using electronic portal imaging for setup. Results: At a median follow-up of 12.2 months, all patients had a complete response in the bladder and one patient had a pelvic nodal recurrence. No patient developed treatment related grade 3 toxicity. Post treatment MVCT scans (n=315) were used to generate margins for centers with varying resources. Overall, the margin needed to encompass the anterior and superior walls 85 to 95% of the time was more than the other walls (Table, margins for six walls in cm). Maximum geographical miss in spite of IGRT was noted for the superior (13.8%) and anterior walls (10.3%). Conclusions: Plan of the day ART is a feasible and promising technique for optimal treatment and dose escalation in bladder cancer. [Table: see text] No significant financial relationships to disclose.

Practical Aspects of Implementation of Helical Tomotherapy for Intensity-modulated and Image-guided Radiotherapy

2010 ◽  
Vol 22 (4) ◽  
pp. 294-312 ◽  
Author(s):  
N.G. Burnet ◽  
E.J. Adams ◽  
J. Fairfoul ◽  
G.S.J. Tudor ◽  
A.C.F. Hoole ◽  
...  
Keyword(s):  
Helical Tomotherapy ◽  
Image Guided Radiotherapy ◽  
Image Guided ◽  
Intensity Modulated

scholarly journals Clinical outcome of image-guided adaptive radiotherapy in the treatment of lung cancer patients

2015 ◽  
Vol 54 (9) ◽  
pp. 1430-1437 ◽  
Author(s):  
Marie Tvilum ◽  
Azza A. Khalil ◽  
Ditte S. Møller ◽  
Lone Hoffmann ◽  
Marianne M. Knap
Keyword(s):  
Lung Cancer ◽  
Clinical Outcome ◽  
Cancer Patients ◽  
Adaptive Radiotherapy ◽  
Lung Cancer Patients ◽  
Image Guided

EP-1412: Image guided adaptive radiotherapy: A practical method to estimate rectal and bladder dose in prostate treatment

2014 ◽  
Vol 111 ◽  
pp. S126
Author(s):  
S. Castiglioni ◽  
G. Maffucci ◽  
F. Cammarano ◽  
C. Plasmati ◽  
E. Di Betta ◽  
...  
Keyword(s):  
Practical Method ◽  
Adaptive Radiotherapy ◽  
Image Guided
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