scholarly journals Population-Based Screening of Children for Specific Speech and Language Impairment in Germany: A Systematic Review

2011 ◽  
Vol 63 (5) ◽  
pp. 247-263 ◽  
Author(s):  
Jürgen Kasper ◽  
Julia Kreis ◽  
Fülöp Scheibler ◽  
Delia Möller ◽  
Guido Skipka ◽  
...  
Keyword(s):  
Systematic Review ◽  
Language Impairment ◽  
Population Based ◽  
Speech And Language ◽  
Speech And Language Impairment

scholarly journals Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review

2020 ◽  
Vol 29 (3) ◽  
pp. 1674-1701 ◽  
Author(s):  
Lindsay K. Butler ◽  
Swathi Kiran ◽  
Helen Tager-Flusberg
Keyword(s):  
Systematic Review ◽  
Infrared Spectroscopy ◽  
Life Span ◽  
Near Infrared Spectroscopy ◽  
Systematic Reviews ◽  
Language Impairment ◽  
Near Infrared ◽  
Speech And Language ◽  
Functional Near Infrared Spectroscopy ◽  
Speech And Language Impairment

Purpose Functional brain imaging is playing an increasingly important role in the diagnosis and treatment of communication disorders, yet many populations and settings are incompatible with functional magnetic resonance imaging and other commonly used techniques. We conducted a systematic review of neuroimaging studies using functional near-infrared spectroscopy (fNIRS) with individuals with speech or language impairment across the life span. We aimed to answer the following question: To what extent has fNIRS been used to investigate the neural correlates of speech-language impairment? Method This systematic review was preregistered with PROSPERO, the international prospective register of systematic reviews (CRD42019136464). We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol for preferred reporting items for systematic reviews. The database searches were conducted between February and March of 2019 with the following search terms: (a) fNIRS or functional near-infrared spectroscopy or NIRS or near-infrared spectroscopy, (b) speech or language, and (c) disorder or impairment or delay. Results We found 34 fNIRS studies that involved individuals with speech or language impairment across nine categories: (a) autism spectrum disorders; (b) developmental speech and language disorders; (c) cochlear implantation and deafness; (d) dementia, dementia of the Alzheimer's type, and mild cognitive impairment; (e) locked-in syndrome; (f) neurologic speech disorders/dysarthria; (g) stroke/aphasia; (h) stuttering; and (i) traumatic brain injury. Conclusions Though it is not without inherent challenges, fNIRS may have advantages over other neuroimaging techniques in the areas of speech and language impairment. fNIRS has clinical applications that may lead to improved early and differential diagnosis, increase our understanding of response to treatment, improve neuroprosthetic functioning, and advance neurofeedback.

Speech and language impairment and oromotor dyspraxia due to deletion of 7q31 that involvesFOXP2

2006 ◽  
Vol 140A (5) ◽  
pp. 509-514 ◽  
Author(s):  
Susan Zeesman ◽  
Małgorzata J.M. Nowaczyk ◽  
Ikuko Teshima ◽  
Wendy Roberts ◽  
Janis Oram Cardy ◽  
...  
Keyword(s):  
Language Impairment ◽  
Speech And Language ◽  
Speech And Language Impairment

Pitch and Timing Abilities in Inherited Speech and Language Impairment

2000 ◽  
Vol 75 (1) ◽  
pp. 34-46 ◽  
Author(s):  
Katherine J. Alcock ◽  
Richard E. Passingham ◽  
Kate Watkins ◽  
Faraneh Vargha-Khadem
Keyword(s):  
Language Impairment ◽  
Speech And Language ◽  
Speech And Language Impairment

scholarly journals Metabolic and Structural Signatures of Speech and Language Impairment in Corticobasal Syndrome: A Multimodal PET/MRI Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Jacy Bezerra Parmera ◽  
Isabel Junqueira de Almeida ◽  
Marcos Castello Barbosa de Oliveira ◽  
Marcela Lima Silagi ◽  
Camila de Godoi Carneiro ◽  
...  
Keyword(s):  
Language Impairment ◽  
Fdg Pet ◽  
Verbal Fluency ◽  
Inferior Frontal Gyrus ◽  
Premotor Cortex ◽  
Corticobasal Syndrome ◽  
Speech And Language ◽  
Positive Correlation ◽  
Major Cluster ◽  
Speech And Language Impairment

Introduction: Corticobasal syndrome (CBS) is a progressive neurological disorder related to multiple underlying pathologies, including four-repeat tauopathies, such as corticobasal degeneration and progressive supranuclear palsy, and Alzheimer's disease (AD). Speech and language are commonly impaired, encompassing a broad spectrum of deficits. We aimed to investigate CBS speech and language impairment patterns in light of a multimodal imaging approach.Materials and Methods: Thirty-one patients with probable CBS were prospectively evaluated concerning their speech–language, cognitive, and motor profiles. They underwent positron emission tomography with [18F]fluorodeoxyglucose (FDG-PET) and [11C]Pittsburgh Compound-B (PIB-PET) on a hybrid PET-MRI machine to assess their amyloid status. PIB-PET images were classified based on visual and semi-quantitative analyses. Quantitative group analyses were performed on FDG-PET data, and atrophy patterns on MRI were investigated using voxel-based morphometry (VBM). Thirty healthy participants were recruited as imaging controls.Results: Aphasia was the second most prominent cognitive impairment, presented in 67.7% of the cases, following apraxia (96.8%). We identified a wide linguistic profile, ranging from nonfluent variant-primary progressive aphasia to lexical–semantic deficits, mostly with impaired verbal fluency. PIB-PET was classified as negative (CBS-A– group) in 18/31 (58%) and positive (CBS-A+ group) in 13/31 (42%) patients. The frequency of dysarthria was significantly higher in the CBS-A– group than in the CBS-A+ group (55.6 vs. 7.7%, p = 0.008). CBS patients with dysarthria had a left-sided hypometabolism at frontal regions, with a major cluster at the left inferior frontal gyrus and premotor cortex. They showed brain atrophy mainly at the opercular frontal gyrus and putamen. There was a positive correlation between [18F]FDG uptake and semantic verbal fluency at the left inferior (p = 0.006, R2 = 0.2326), middle (0.0054, R2 = 0.2376), and superior temporal gyri (p = 0.0066, R2 = 0.2276). Relative to the phonemic verbal fluency, we found a positive correlation at the left frontal opercular gyrus (p = 0.0003, R2 = 0.3685), the inferior (p = 0.0004, R2 = 0.3537), and the middle temporal gyri (p = 0.0001, R2 = 0.3993).Discussion: In the spectrum of language impairment profile, dysarthria might be helpful to distinguish CBS patients not related to AD. Metabolic and structural signatures depicted from this feature provide further insights into the motor speech production network and are also helpful to differentiate CBS variants.

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