Daily Short-Term Intratympanic Dexamethasone Treatment Alone as an Initial or Salvage Treatment for Idiopathic Sudden Sensorineural Hearing Loss

2011 ◽  
Vol 16 (3) ◽  
pp. 191-197 ◽  
Author(s):  
Seiji Kakehata ◽  
Akira Sasaki ◽  
Kazunori Futai ◽  
Rei Kitani ◽  
Hideichi Shinkawa
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Salvage Treatment ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Dexamethasone Treatment ◽  
Short Term ◽  
Intratympanic Dexamethasone

Simultaneous versus Subsequent Intratympanic Dexamethasone for Idiopathic Sudden Sensorineural Hearing Loss

2011 ◽  
Vol 145 (6) ◽  
pp. 1016-1021 ◽  
Author(s):  
Moo Kyun Park ◽  
Chi Kyou Lee ◽  
Kye Hoon Park ◽  
Jong Dae Lee ◽  
Chan Goo Lee ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Dexamethasone Treatment ◽  
Early Recovery ◽  
Dexamethasone Group ◽  
Number Of Patients ◽  
Hearing Recovery ◽  
Intratympanic Dexamethasone

Objective. The authors compared the efficacy of simultaneous and subsequent intratympanic dexamethasone injections for the treatment of idiopathic sudden sensorineural hearing loss. Study Design. Prospective randomized controlled multicenter study. Setting. Three tertiary university hospitals. Subjects and Methods. In the simultaneous intratympanic dexamethasone group, intratympanic dexamethasone was given initially with systemic steroids. In the subsequent intratympanic dexamethasone group, intratympanic dexamethasone was given 7 days after systemic treatment. The authors compared hearing outcomes between the groups according to Siegel’s criteria and frequency (0.25, 0.5, 1, 2, 3, 4, 6, and 8 kHz). Results. A total of 88 patients were analyzed in this study. There was no difference between the groups in hearing recovery according to Siegel’s criteria or frequencies. Neither recovery time nor early recovery differed between the groups. In the subsequent intratympanic dexamethasone group, 15 patients showed hearing recovery within 7 days and did not need intratympanic dexamethasone treatment. After intratympanic dexamethasone treatment, >28% (25/88) of the patients complained of otalgia, transient dizziness, ear fullness, and headache. Five percent of the patients showed small, transient perforations and otorrhea during intratympanic dexamethasone treatment. Conclusions. Simultaneous intratympanic dexamethasone did not confer an additional hearing gain or earlier recovery rate compared with subsequent intratympanic dexamethasone. A considerable number of patients did not need intratympanic dexamethasone for idiopathic sudden sensorineural hearing loss, and some patients experienced unnecessary side effects due to intratympanic dexamethasone. Therefore, the use of intratympanic dexamethasone is recommended only for subsequent or salvage treatment of idiopathic sudden sensorineural hearing loss after systemic steroid treatment.

Noninvasive intratympanic dexamethasone treatment for sudden sensorineural hearing loss

2012 ◽  
Vol 132 (6) ◽  
pp. 583-589 ◽  
Author(s):  
Qiuying Zhang ◽  
Haitao Song ◽  
Hao Peng ◽  
Xuemei Yang ◽  
Junmei Zhou ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Dexamethasone Treatment ◽  
Intratympanic Dexamethasone
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