Elevated Pro-Brain Natriuretic Peptide, Troponin T and Malnutrition Inflammatory Score in Chronic Hemodialysis Patients with Overt Cardiovascular Disease

2011 ◽  
Vol 117 (3) ◽  
pp. c198-c205 ◽  
Author(s):  
Hernán Trimarchi ◽  
Alexis Muryan ◽  
Vicente Campolo-Girard ◽  
Mariana Dicugno ◽  
Nanci Barucca ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Troponin T ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Inflammatory Score

scholarly journals Moderate elevations of high-sensitivity cardiac troponin I and B-type natriuretic peptide in chronic hemodialysis patients are associated with mortality

2013 ◽  
Vol 51 (6) ◽  
Author(s):  
Daniël A. Geerse ◽  
Miranda van Berkel ◽  
Steffie Vogels ◽  
Jeroen P. Kooman ◽  
Constantijn J.A.M. Konings ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Total Mortality ◽  
High Sensitivity ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Cardiac Troponin I ◽  
Moderate Elevation

AbstractSeveral biomarkers are associated with mortality in hemodialysis patients. In particular, elevated cardiac troponin T and B-type natriuretic peptide (BNP) are strong predictors of mortality; however, less is known about cardiac troponin I (cTnI). Elevated troponin I is detected in many hemodialysis patients, but the association of moderate elevations with mortality is unclear.The relation between mortality and cTnI, using a high-sensitivity cTnI assay, as well as BNP and C-reactive protein (CRP) was evaluated in 206 chronic hemodialysis patients.Median follow-up was 28 months with a total mortality of 35%. Mortality was significantly associated with elevated cTnI, BNP and CRP. Even patients with only moderate elevation of cTnI (0.01–0.10 μg/L) showed 2.5-fold increased mortality. Interestingly, hazard ratios for mortality for single (random) measurements were comparable to those for mean/median measurements. Subsequently, subgroup analysis based on combined markers was performed. Patients with both cTnI <0.01 μg/L and BNP in the first quartile had 100% survival. Patients with either cTnI <0.01 μg/L or BNP in the lowest quartile had significantly lower mortality (12% and 13%, respectively) than patients with BNP levels in the second quartile or higher and cTnI of 0.01–0.05 μg/L and patients with cTnI ≥0.05 μg/L (mortality 46 and 58%, respectively).A combination of moderate elevation of cTnI and BNP provided additional prognostic value. A single measurement of these biomarkers performed comparably to the mean/median of multiple measurements.

The mature form of adrenomedullin correlates with brain natriuretic peptide in plasma of chronic hemodialysis patients

2002 ◽  
Vol 57 (06) ◽  
pp. 444-451 ◽  
Author(s):  
T. Suda ◽  
A. Osajima ◽  
M. Iwamoto ◽  
H. Anai ◽  
M. Tamura ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Mature Form

1518: Troponin T and N-Terminal Pro-Brain Natriuretic Peptide (PRO-BNP) Changes in Patients Undergoing Transurethral Resection of The Prostate (TURP)

2004 ◽  
Vol 171 (4S) ◽  
pp. 399-400
Author(s):  
Ramaswamy Manikandan ◽  
Calvin Nathaniel ◽  
Ravi Gullipalli ◽  
Adebanji Adeyoju ◽  
Stephen C.W. Brown ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Transurethral Resection ◽  
Troponin T
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