Oxidative Stress in Benign Prostatic Hyperplasia and Prostate Cancer

2010 ◽  
Vol 85 (3) ◽  
pp. 328-333 ◽  
Author(s):  
Gianna Pace ◽  
Caterina Di Massimo ◽  
Daniela De Amicis ◽  
Carlo Corbacelli ◽  
Laura Di Renzo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia

scholarly journals Role of gangliosides in prostate pathology

2016 ◽  
Vol 19 (1) ◽  
pp. 10-15
Author(s):  
Ilinca Nicolae ◽  
◽  
Corina-Daniela Ene ◽  
Simona Roxana Georgescu ◽  
◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Differential Diagnosis ◽  
Benign Prostatic Hyperplasia ◽  
Molecular Pathology ◽  
Potential Role ◽  
Prostatic Hyperplasia ◽  
Immunologic Markers ◽  
Immunological Interactions

Molecular pathology of benign prostatic hyperplasia is multifactorial and involves endocrine, biochemical, immunological interactions. The mechanisms involved in the onset and progression of benign prostatic hyperplasia are: infections, 50 years of age, hormones and neurotransmitters imbalances, inflammation, oxidative stress. The potential role of glycosylation in the pathogenesis of prostate disease has been neglected. In this study we documented the profile of gangliosides in normal and pathological prostatic tissues together with the pathologic changes seen in the level of extracellular gangliosides in patients with prostate pathology. Analysis of the data in the literature suggests that gangliosides may represent immunologic markers useful in the differential diagnosis between prostate cancer and benign prostatic hyperplasia.

Oxidative Stress in Benign Prostatic Hyperplasia: A Systematic Review

2014 ◽  
Vol 94 (3) ◽  
pp. 249-254 ◽  
Author(s):  
Paola Lucia Minciullo ◽  
Antonino Inferrera ◽  
Michele Navarra ◽  
Gioacchino Calapai ◽  
Carlo Magno ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Free Radicals ◽  
Benign Prostatic Hyperplasia ◽  
Defense Mechanisms ◽  
Cellular Proliferation ◽  
Prostatic Hyperplasia ◽  
Dietary Factors ◽  
Key Words Oxidative Stress

Background: Several parameters including inflammatory mediators, hormones, dietary factors, inflammatory genes, and oxidative stress (OS) have been considered to play a role in the development of benign prostatic hyperplasia (BPH). Prostate tissue damage and OS may lead to compensatory cellular proliferation with resulting hyperplastic growth. Methods: We searched MEDLINE for articles in English published up to March 2014 using the key words ‘oxidative stress', ‘antioxidants' and ‘benign prostatic hyperplasia'. Results: Prostatic inflammation can cause the generation of free radicals. The extent of oxidative damage can be exacerbated by a decreased efficiency of antioxidant defense mechanisms. The balance between OS and the antioxidant component also has a role in developing prostate disease. Several works show the role of oxidant products and of depletion of antioxidant substances in BPH patients. It is accepted that free radicals play a role in carcinogenesis and that BPH should be considered a premalignant condition which may evolve into prostate cancer. High OS parameters and low antioxidant activity are more prominent in prostate cancer patients compared with BPH and controls. Conclusions: Further studies are needed to clarify the potential role of antioxidants in BPH also in view of preventing the progression to prostate cancer.

scholarly journals The evaluation of oxidative stress parameters in the benign prostatic hyperplasia, prostatitis and prostate cancer

2019 ◽  
Vol 11 (3) ◽  
pp. 315-321 ◽  
Author(s):  
Aliseydi Bozkurt ◽  
Cebrail Gürsul ◽  
Merve Aydin ◽  
İlyas Sayar ◽  
Mehmet Karabakan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

scholarly journals Oxidative stress and antioxidant status in non-metastatic prostate cancer and benign prostatic hyperplasia

2006 ◽  
Vol 39 (2) ◽  
pp. 176-179 ◽  
Author(s):  
Ahmet Aydin ◽  
Zorica Arsova-Sarafinovska ◽  
Ahmet Sayal ◽  
Ayse Eken ◽  
Onur Erdem ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Antioxidant Status ◽  
Metastatic Prostate Cancer ◽  
Prostatic Hyperplasia

468: Polymorphic CA Repeats in IGF-I Gene is a Common Genetic Modifier in the Etiology of Prostate Cancer and Benign Prostatic Hyperplasia

2004 ◽  
Vol 171 (4S) ◽  
pp. 125-125
Author(s):  
Lizhong Wang ◽  
Kazunari Sato ◽  
Norihiko Tsuchiya ◽  
Chikara Ohyama ◽  
Shigeru Satoh ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Genetic Modifier ◽  
Prostatic Hyperplasia ◽  
Igf I ◽  
I Gene

scholarly journals Light-controlled calcium signalling in prostate cancer and benign prostatic hyperplasia

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Vipin Sharma ◽  
Rita Rana ◽  
Ruma Baksi ◽  
Swapnil P. Borse ◽  
Manish Nivsarkar
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Calcium Signalling ◽  
Prostatic Hyperplasia
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