scholarly journals Diet, Nutrition and Modulation of Genomic Expression in Fetal Origins of Adult Disease

2010 ◽  
pp. 56-72 ◽  
Author(s):  
Alan A. Jackson ◽  
Graham C. Burdge ◽  
Karen A. Lillycrop
Keyword(s):  
Fetal Origins ◽  
Genomic Expression ◽  
Adult Disease

scholarly journals Diet, Nutrition and Modulation of Genomic Expression in Fetal Origins of Adult Disease

2010 ◽  
Vol 3 (4-6) ◽  
pp. 192-208 ◽  
Author(s):  
Alan A. Jackson ◽  
Graham C. Burdge ◽  
Karen A. Lillicrop
Keyword(s):  
Fetal Origins ◽  
Genomic Expression ◽  
Adult Disease

scholarly journals Fetal origins of adult disease

1999 ◽  
Vol 81 (1) ◽  
pp. 5-6 ◽  
Author(s):  
Simon C. Langley-Evans
Keyword(s):  
Fetal Origins ◽  
Adult Disease

scholarly journals Homage to the ‘H’ in developmental origins of health and disease

2016 ◽  
Vol 8 (1) ◽  
pp. 8-29 ◽  
Author(s):  
C. S. Rosenfeld
Keyword(s):  
Female Offspring ◽  
Postnatal Period ◽  
Environmental Chemicals ◽  
Primary Concern ◽  
Developmental Origins ◽  
Adult Health ◽  
Fetal Origins ◽  
Adult Disease ◽  
Remediation Strategies ◽  
Health And Disease

Abundant evidence exists linking maternal and paternal environments from pericopconception through the postnatal period to later risk to offspring diseases. This concept was first articulated by the late Sir David Barker and as such coined the Barker Hypothesis. The term was then mutated to Fetal Origins of Adult Disease and finally broadened to developmental origins of adult health and disease (DOHaD) in recognition that the perinatal environment can shape both health and disease in resulting offspring. Developmental exposure to various factors, including stress, obesity, caloric-rich diets and environmental chemicals can lead to detrimental offspring health outcomes. However, less attention has been paid to date on measures that parents can take to promote the long-term health of their offspring. In essence, have we neglected to consider the ‘H’ in DOHaD? It is the ‘H’ component that should be of primary concern to expecting mothers and fathers and those seeking to have children. While it may not be possible to eliminate exposure to all pernicious factors, prevention/remediation strategies may tip the scale to health rather than disease. By understanding disruptive DOHaD mechanisms, it may also illuminate behavioral modifications that parents can adapt before fertilization and throughout the neonatal period to promote the lifelong health of their male and female offspring. Three possibilities will be explored in the current review: parental exercise, probiotic supplementation and breastfeeding in the case of mothers. The ‘H’ paradigm should be the focus going forward as a healthy start can indeed last a lifetime.

scholarly journals The fetal origins of adult disease

BMJ ◽  
2001 ◽  
Vol 322 (7283) ◽  
pp. 375-376 ◽  
Author(s):  
R. Robinson
Keyword(s):  
Fetal Origins ◽  
Adult Disease

scholarly journals The fetal origins of adult disease: a narrative review of the epidemiological literature

2012 ◽  
Vol 3 (8) ◽  
pp. 1-7 ◽  
Author(s):  
Jens Christoffer Skogen ◽  
Simon Øverland
Keyword(s):  
Narrative Review ◽  
Fetal Origins ◽  
Adult Disease
Sign in / Sign up

Export Citation Format

Share Document