Features of Optical Coherence Tomography Are Predictive of Visual Outcomes after Intravitreal Bevacizumab Injection for Diabetic Macular Edema

2010 ◽  
Vol 224 (6) ◽  
pp. 374-380 ◽  
Author(s):  
Mi In Roh ◽  
Ji Hyun Kim ◽  
Oh Woong Kwon
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Intravitreal Bevacizumab ◽  
Optical Coherence ◽  
Visual Outcomes ◽  
Intravitreal Bevacizumab Injection ◽  
Bevacizumab Injection

scholarly journals Optical coherence tomography findings predictive of response to treatment in diabetic macular edema

2018 ◽  
Vol 46 (11) ◽  
pp. 4455-4464 ◽  
Author(s):  
Young Joo Cho ◽  
Dong Hyun Lee ◽  
Min Kim
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Serous Retinal Detachment ◽  
Intravitreal Bevacizumab ◽  
Internal Limiting Membrane ◽  
Response To Treatment ◽  
Optical Coherence ◽  
Sd Oct

Objective To evaluate the short-term efficacy of intravitreal bevacizumab (IVB) and posterior sub-tenon triamcinolone injections (PSTI) on the basis of spectral-domain optical coherence tomography (SD-OCT) patterns in diabetic macular edema (DME). Methods We retrospectively reviewed 73 eyes of 73 patients with DME. Based on the presence of serous retinal detachment (SRD), eyes were categorized into two groups, and either IVB or PSTI treatment was performed. Central macular thickness (CMT) and the degree of SRD were assessed preoperatively and 1 month postoperatively. The severity of intraretinal edema was approximated based on the distance from the external limiting membrane to the internal limiting membrane. Results In eyes with SRD, reduction of SRD was greater with IVB than with PSTI. Moreover, reduction of intraretinal edema was greater with PSTI than with IVB. In eyes without SRD, PSTI achieved greater CMT reduction, compared with IVB. Conclusions In DME patients with SRD, IVB achieved greater reduction of SRD, compared with PSTI; however, intraretinal edema responded more favorably to PSTI, regardless of the presence of SRD. Our results suggest that the classification of DME based on OCT findings may be useful to predict responses to IVB or PSTI treatments.

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