Migraine with Aura Is a Risk Factor for Cervical Artery Dissection: A Case-Control Study

2010 ◽  
Vol 30 (1) ◽  
pp. 36-40 ◽  
Author(s):  
V. Artto ◽  
T.M. Metso ◽  
A.J. Metso ◽  
J. Putaala ◽  
E. Haapaniemi ◽  
...  
Keyword(s):  
Risk Factor ◽  
Migraine With Aura ◽  
Case Control Study ◽  
Case Control ◽  
Artery Dissection ◽  
Cervical Artery Dissection ◽  
Cervical Artery ◽  
Control Study

Migraine and the risk of cervical artery dissection: A case-control study

Neurology ◽  
2002 ◽  
Vol 59 (3) ◽  
pp. 435-437 ◽  
Author(s):  
C. Tzourio ◽  
L. Benslamia ◽  
B. Guillon ◽  
S. Aidi ◽  
M. Bertrand ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Artery Dissection ◽  
Cervical Artery Dissection ◽  
Cervical Artery ◽  
Control Study

scholarly journals Recent Infection And Risk of Spontaneous Cervical Artery Dissection: A Case-Control Study

Stroke ◽  
2001 ◽  
Vol 32 (suppl_1) ◽  
pp. 361-361
Author(s):  
Benoit Guillon ◽  
Christophe Tzourio ◽  
Karine Berthet ◽  
Lamia Benslamia ◽  
Christian Lucas ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Strenuous Exercise ◽  
Artery Dissection ◽  
Cervical Artery Dissection ◽  
Minor Trauma ◽  
Recent Infection ◽  
Cervical Artery ◽  
Control Study

P124 Background and Purpose: Spontaneous cervical artery dissection (SCAD) is a major cause of stroke in young adults, for which an underlying arteriopathy related to a generalized extracellular matrix defect could often be a predisposing condition. As triggering factors such as minor trauma/strenuous exercise or infection may be implicated in the occurrence of SCAD, we conducted a case-control study to assess the relationship between recent infection and risk of SCAD. Methods: Forty-eight patients with SCAD and 52 patients with ischemic stroke from other causes (controls) were recruited prospectively and consecutively from two centers during an 18-month period. Controls were included if they were roughly comparable to cases for sex and age. To analyze the history of recent infection (within one month before SCAD or ischemia), a face-to-face interview, with a structured questionnaire focused on symptoms typical of infection, was performed as soon as possible after admission. Results: Patients and controls were comparable for age (44.6 (7.5) vs 45.2 (9.1), P=0.72) and sex distribution (46% of women vs 43%, P=0.81). Recent infection was found in 31.3% (15/48) of patients with SCAD and 13.5% (7/52) of controls, yielding a crude odds ratio of 2.92 (95% CI, 1.07 to 8.74; P=0.032). In a logistic model adjusted for age, sex, center, educational level and migraine, the odds ratio for recent infection in cases was 3.05 (95% CI, 1.06 to 8.74; P=0.038). Conclusion: This prospective case-control study showed a significant association between recent infection and SCAD, consistent with the triggering role of an infectious process in the occurrence of SCAD.

History of Migraine and the Risk of Spontaneous Cervical Artery Dissection

Cephalalgia ◽  
2005 ◽  
Vol 25 (8) ◽  
pp. 575-580 ◽  
Author(s):  
A Pezzini ◽  
F Granella ◽  
M Grassi ◽  
C Bertolino ◽  
E Del Zotto ◽  
...  
Keyword(s):  
Family History ◽  
Migraine Without Aura ◽  
Case Control Study ◽  
Case Control ◽  
Personal History ◽  
Artery Dissection ◽  
Cervical Artery Dissection ◽  
Cervical Artery ◽  
History Of ◽  
Control Study

The pathophysiology of spontaneous cervical artery dissection (sCAD) is largely unknown. An association with migraine has been suggested, but not definitively proven. In the setting of a hospital-based prospective case-control study we assessed personal and family history of migraine in 72 patients with sCAD, 72 patients with cerebral infarct unrelated to a CAD (non-CAD) and 72 control subjects. Personal history of migraine was significantly associated to sCAD compared to non-CAD (59.7% vs. 30.6%; OR 3.14; 95% CI 1.41-7.01) and controls (18.1%; OR 7.41; 95% CI 3.11-17.64). As opposed to migraine with aura, migraine without aura was significantly more frequent among sCAD than among non-CAD (56.9% vs. 25.0%; OR 3.91; 95% CI 1.71-8.90) and controls (12.5%; OR 9.84; 95% CI 3.85-25.16). Similar results were observed when the frequencies of family history of migraine were compared. These findings are consistent with the hypothesis that migraine may represent a predisposing condition for sCAD.

Percutaneous coronary intervention in spontaneous coronary artery dissection: a case-control study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Kotecha ◽  
A.D.P.E Premawardhana ◽  
M Garcia-Guimaraes ◽  
D Pellegrini ◽  
A.D Wood ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Case Control Study ◽  
Case Control ◽  
Artery Dissection ◽  
Funding Source ◽  
Complication Rates ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Control Study ◽  
Reduced Flow

Abstract Background Spontaneous Coronary Artery Dissection (SCAD) is an important cause of acute coronary syndrome particularly in young-middle aged women. Revascularisation is challenging due to an underlying disrupted and friable coronary vessel wall leading to widely reported worse outcomes than for atherosclerotic coronary disease. Therefore, a conservative approach where possible is favoured however in some cases haemodynamic instability, ongoing ischaemia and reduced distal flow mandates consideration of revascularisation. Purpose To compare SCAD survivors managed with PCI or conservatively in terms of presentation characteristics, complications and long-term outcomes. Methodology and results 226 angiographically confirmed SCAD survivors (95% female,47±9.7yrs) who underwent PCI were compared in a case control study with two hundred and twenty-five angiographically confirmed SCAD survivors (92% female, 49±9.9yrs) who were conservatively managed. Patients were recruited from UK, Spanish and Dutch SCAD registries and both groups were well matched in terms of baseline demographics. Those treated with PCI were more likely to present with proximal SCAD (30.8% vs 7.6% P<0.01) and ST elevation myocardial infarction (STEMI) or cardiac arrest with reduced flow (32.3% vs 6.3% P<0.01). Intervention was performed with stents in 72.4%, plain old balloon angioplasty in 21.1% and wiring in 6.4% of cases and more often for multi-segment disease (40.8% vs 26.3% P<0.01). In cases with initial reduced flow undergoing PCI an improvement in flow was seen in 83%. Analysis of UK PCI cases (n=144) reveal complications in 56 (38.8%). However, when assessed for significance defined by a reduction in flow in a proximal/mid vessel, stent extension into left main stem, iatrogenic dissection requiring PCI and CABG as a consequence of PCI only 13 cases (9%) met criteria. Iatrogenic dissection accounts for the majority (76.9%). SCAD lesion length was associated with presence of complications (P=0.025). There was a non-significant trend towards major adverse cardiovascular events (MACE) occurring more frequently in those undergoing PCI (18% vs 11% P=0.067) driven by revascularisation (5% vs 1% P=0.036). Median follow up was 2.7 years. Conclusions PCI in SCAD is often performed in higher risk patients; in those presenting with reduced flow, the majority demonstrate improvement. Importantly whilst overall complication rates were similar to those widely reported, clinically significant complications were low. Multivariate modelling will reveal factors associated with complications to aid future decision making in this challenging patient group. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): British Heart Foundation

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