scholarly journals Validation of the German Revised Addenbrooke’s Cognitive Examination for Detecting Mild Cognitive Impairment, Mild Dementia in Alzheimer’s Disease and Frontotemporal Lobar Degeneration

2010 ◽  
Vol 29 (5) ◽  
pp. 448-456 ◽  
Author(s):  
P. Alexopoulos ◽  
A. Ebert ◽  
T. Richter-Schmidinger ◽  
E. Schöll ◽  
B. Natale ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Frontotemporal Lobar Degeneration ◽  
Mild Dementia ◽  
Addenbrooke’S Cognitive Examination

scholarly journals Predictors of accidents in people with mild cognitive impairment, mild dementia due to Alzheimer's disease and healthy controls in simulated driving

2020 ◽  
Vol 35 (8) ◽  
pp. 859-869
Author(s):  
Alexandra Economou ◽  
Dimosthenis Pavlou ◽  
Ion Beratis ◽  
Nikolaos Andronas ◽  
Eleonora Papadimitriou ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Healthy Controls ◽  
Mild Dementia ◽  
Simulated Driving

The Mini-Mental State Examination: Czech Norms and Cutoffs for Mild Dementia and Mild Cognitive Impairment due to Alzheimer's Disease

2016 ◽  
Vol 42 (1-2) ◽  
pp. 50-57 ◽  
Author(s):  
Ales Bartos ◽  
Miloslava Raisova
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Mild Dementia ◽  
Dementia Patients ◽  
Early Alzheimer’S Disease ◽  
State Examination

Background: There is a lack of normative studies of the Mini-Mental State Examination (MMSE) for comparison with early Alzheimer's disease (AD) according to new diagnostic criteria. Participants and Methods: We administered the MMSE to normal elderly Czechs and to patients with mild cognitive impairment (MCI) and mild dementia due to AD according to NIA-AA criteria. Results: We established percentile- and standard deviation-based norms for the MMSE from 650 normal seniors (age 69 ± 8 years, education 14 ± 3 years, MMSE score 28 ± 2 points) stratified by education and age. Dementia patients scored significantly lower than the MCI patients and both groups (110 early AD patients) had significantly lower MMSE scores than the normal seniors (22 ± 5 or 25 ± 3 vs. 28 ± 2 points) (p < 0.01). The optimal cutoff was ≤27 points with sensitivity of 86% and specificity of 79% for early detection of AD patients. Conclusion: We provided MMSE norms, several cutoffs, and higher cutoff scores for early AD using recent guidelines.

[P3-441]: THE ADDENBROOKE's COGNITIVE EXAMINATION-REVISED (ACE-R) IN THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER's DISEASE: A PRELIMINARY ANALYSIS

2017 ◽  
Vol 13 (7S_Part_23) ◽  
pp. P1138-P1138
Author(s):  
Viviane Amaral Carvalho ◽  
Luciano Inácio Mariano ◽  
Thais Bento Lima-Silva ◽  
Henrique Cerqueira Guimaraes ◽  
Leonardo Cruz de Souza ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Preliminary Analysis ◽  
Addenbrooke’S Cognitive Examination

Addenbrooke's cognitive examination III: diagnostic utility for mild cognitive impairment and dementia and correlation with standardized neuropsychological tests

2016 ◽  
Vol 29 (1) ◽  
pp. 105-113 ◽  
Author(s):  
Jordi A. Matias-Guiu ◽  
Ana Cortés-Martínez ◽  
Maria Valles-Salgado ◽  
Teresa Rognoni ◽  
Marta Fernández-Matarrubia ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Tests ◽  
Pearson Correlation ◽  
Amnestic Mild Cognitive Impairment ◽  
Visuospatial Function ◽  
Early Stages ◽  
Addenbrooke’S Cognitive Examination

ABSTRACTBackground:Addenbrooke's Cognitive Examination III (ACE-III) is a screening test that was recently validated for diagnosing dementia. Since it assesses attention, language, memory, fluency, and visuospatial function separately, it may also be useful for general neuropsychological assessments. The aim of this study was to analyze the tool's ability to detect early stages of Alzheimer's disease and to examine the correlation between ACE-III scores and scores on standardized neuropsychological tests.Methods:Our study included 200 participants categorized as follows: 25 healthy controls, 48 individuals with subjective memory complaints, 47 patients with amnestic mild cognitive impairment and 47 mild Alzheimer's disease, and 33 patients with other neurodegenerative diseases.Results:The ACE-III memory and language domains were highly correlated with the neuropsychological tests specific to those domains (Pearson correlation coefficient of 0.806 for total delayed recall on the Free and Cued Selective Reminding Test vs. 0.744 on the Boston Naming Test). ACE-III scores discriminated between controls and patients with amnestic mild cognitive impairment (AUC: 0.906), and between controls and patients with mild Alzheimer's disease (AUC: 0.978).Conclusion:Our results suggest that ACE-III is a useful neuropsychological test for assessing the cognitive domains of attention, language, memory, and visuospatial function. It also enables detection of Alzheimer's disease in early stages.

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