Optic Nerve Trauma with Prolonged Blindness Followed by Visual-Evoked Potential

1987 ◽  
Vol 194 (1) ◽  
pp. 40-43 ◽  
Author(s):  
Fabian A. Abraham ◽  
Avraham Spierer ◽  
Michael Blumenthal
Keyword(s):  
Optic Nerve ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Nerve Trauma ◽  
Visual Evoked

scholarly journals Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination

10.3791/52934 ◽  
2015 ◽  
Author(s):  
Yuyi You ◽  
Vivek K. Gupta ◽  
Nitin Chitranshi ◽  
Brittany Reedman ◽  
Alexander Klistorner ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Rat Model ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Potential Recording ◽  
Visual Evoked

scholarly journals Evaluation of Visual Evoked Potential in Psoriasis Vulgaris Patients in a Tertiary Care Centre

2021 ◽  
Vol 8 (6) ◽  
pp. 148-154
Author(s):  
T. N. Vijayalakshmi ◽  
K. Vishnu Priya ◽  
D. Celine
Keyword(s):  
Optic Nerve ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Psoriasis Vulgaris ◽  
Tertiary Care ◽  
Sensory Nerves ◽  
Ophthalmological Examination ◽  
P100 Latency ◽  
Increased Risk ◽  
Visual Evoked

Psoriasis is an immunologically mediated, inflammatory disease with increased risk of painful and destructive arthritis, cardiovascular morbidity and psychosocial challenges. Psoriasis vulgaris is the most common form of psoriasis, seen in approximately 90% of patients. Besides skin, other regions widely involved are bone, cardiovascular system and eye. Psoriatic eye manifestations involve many of the structures of eye; from eyelid till optic nerve. Recording of Visual evoked potential helps in studying the integrity of optic nerve and its abnormality signifies demyelination. The concept Brain skin axis proposed in literature shows involvement of nervous system with immune mediated inflammatory pathway in Psoriasis. During intense inflammatory course, highly dense sensory nerves in plaques trigger the release of neuropeptides, targeting keratinocytes and further nerve damage. With this background, the present study was aimed to assess Optic pathway integrity by Visual Evoked Potential in patients of Psoriasis vulgaris. Materials and Methods: A Case control study was done with Institutional Ethics Committee approval and written informed consent on 100 plaque type psoriatic cases and 50 apparently healthy subjects as controls. Cases were divided into 2 groups based on their disease duration as I – new cases (1 to 5 years), II – old cases (6 to 10 years). Psoriatic patients treated with UVB and Methotrexate and with relapse of both gender of 15 to 35 years were included in the study. Patients with Diabetes Mellitus, Hypertension, any other chronic illness and autoimmune disease, severe forms of psoriasis, patients on oral steroids, and with H /O ocular diseases, eye surgery and neurological illness were excluded from the study. The mean Psoriasis Area Severity Index (PASI) was 16.09 ± 11.11. According to PASI score, the cases were categorised as <10 – mild; >11-20 – moderate; and>21 – severe. Clinical and ophthalmological examination was done for study participants. After proper instructions to patients for VEP procedure, VEP was recorded using Physiopac –NEURO PERFECT EMG 2000 SYSTEM. P100 latency of controls and cases was taken for analysis and analysed using SPSS 21.0 version. Results: There was increase in P100 latency of cases when compared to controls. P100 latency progressively increases as the severity of disease increases. Conclusion: Increased latency of P100 is a sign for demyelination. As this is seen in the present study, in psoriatic patients, there is a probability of optic nerve involvement during active state of disease. Keywords: Psoriasis, VEP, P100, PASI.

Visual evoked potentials (VEP) studies in primary open glaucoma

2021 ◽  
Vol 19 (3) ◽  
pp. 28-31
Author(s):  
Bhagya V ◽  
Keyword(s):  
Optic Nerve ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Pathway ◽  
Nerve Damage ◽  
Open Angle ◽  
Optic Nerve Damage ◽  
Visual Evoked

Background: With increasing prevalance of primary open angle glaucoma and optic nerve damage as a consequence of this, there is a need for early diagnosis and prevention of optic nerve damage. VEP, the potential recorded from the occipital region in response to the visual stimuli can be used for early detection of the primary open angle glaucoma. Visual evoked potential (VEP) is a non invasive method to assess the visual pathway. The present study was done to evaluate the impact of primary open angle glaucoma on central nervous system particularly, visual pathway. Methods: 30 primary open angle glaucoma patients attending outpatient department of ophthalmology department, SS hospital, Davanagere and 30 age matched controls selected randomly from general population were subjected to Visual evoked potential. Parameters for VEP such as latencies of waves N70, P100, and N155 peak-to-peak amplitudes of waves N70-P100 and P100-N155 were assessed and analyzed by using unpaired student-T test for comparison between cases and controls. Results: The present study observed that the there was a statistically significant increase in P100 latency in cases compared to the controls. And also there was a statistically significant decrease in N70 and P100 amplitude in cases compared to the controls. Conclusion: The present study correlates with earlier findings that visual pathway gets involved in primary open angle glaucoma even before the development of neuropathy which can be detected using VEP. Meticulous follow-up is a must to prevent the complications of primary open angle glaucoma, so that further damage can be prevented.

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