The Correlation Between Human Growth Hormone (HGH) Concentration in Blood Plasma and the Evolution of Diabetic Retinopathy

1972 ◽  
Vol 165 (1) ◽  
pp. 71-77 ◽  
Author(s):  
R. Sévin
Keyword(s):  
Growth Hormone ◽  
Diabetic Retinopathy ◽  
Blood Plasma ◽  
Human Growth Hormone ◽  
Human Growth ◽  
In Blood Plasma

STIMULATION OF IMMUNOREACTIVE INSULIN AND HUMAN GROWTH HORMONE RELEASE BY ADMINISTRATION OF ARGININE IN PATIENTS WITH DIABETIC RETINOPATHY

1972 ◽  
Vol 70 (4) ◽  
pp. 719-730 ◽  
Author(s):  
W. Waldhäusl
Keyword(s):  
Growth Hormone ◽  
Diabetic Retinopathy ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Immunoreactive Insulin ◽  
Insulinogenic Index ◽  
Hormone Release ◽  
Arginine Hydrochloride ◽  
The Mean ◽  
Secretory Capacity

ABSTRACT The effect of arginine hydrochloride (30 g), given twice at 90 min intervals, on the release of immunoreactive insulin and of human growth hormone was studied in healthy subjects (HS), in diabetics without and with various degrees of retinopathy and in acromegalics. The insulinogenic index estimated by the ratio of μU IRI per ml/mg per 100 ml of blood glucose was maximal in HS after the first administration of arginine. It was highest in acromegalics and diminished in all the diabetic subjects. The release of human growth hormone as estimated by the mean sum of increments above the basal levels (x̄ + sem) during period I and II was 80.2±15 ng/ml and 59.0±18 ng/ml in HS (n = 7), 38±8.6 ng/ml and 36±16.3 ng/ml in diabetics without retinopathy (n = 9), 4.2±0.4 ng/ml and 19±7 ng/ml in insulin treated diabetics with retinopathy (n = 9), and 22.7±10.7 ng/ml and 46±10.5 ng/ml in orally treated diabetics with retinopathy (n = 7). Patients suffering from proliferative retinopathy (n = 9) exhibited values of 32.8±10.6 ng/ml during period I and 43.5±10.6 ng/ml during period II. The secretory response of HGH to arginine in acromegalics (n = 6) was not significant. The data reported suggest an impaired secretory capacity for the release of human growth hormone to the administration of arginine in patients with diabetic retinopathy. The observations do not support the hypothesis that an exaggerated release of HGH plays a role in the development of diabetic retinopathy.

Effect of pituitary ultrasonic treatment on plasma human growth hormone levels in diabetic retinopathy and acromegaly

1975 ◽  
Vol 12 (2) ◽  
pp. 137-149
Author(s):  
Michele Muggeo ◽  
Maurizio Molinari ◽  
Domenico Fedele ◽  
Antonio Tiengo ◽  
Gaetano Crepaldi
Keyword(s):  
Growth Hormone ◽  
Diabetic Retinopathy ◽  
Human Growth Hormone ◽  
Ultrasonic Treatment ◽  
Human Growth ◽  
Hormone Levels

LIPOLYTIC ACTIVITY OF ENZYME DIGESTED HUMAN GROWTH HORMONE

1965 ◽  
Vol 49 (3_Suppl) ◽  
pp. S143
Author(s):  
Zvi Laron ◽  
Avivah Kowadlo-Silbergeld
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Lipolytic Activity ◽  
Human Growth

The minimal amino acid sequence of the insulin-potentiating fragments of human growth hormone: its mechanism of action

Diabetes ◽  
1980 ◽  
Vol 29 (10) ◽  
pp. 782-787 ◽  
Author(s):  
F. M. Ng ◽  
J. Bornstein ◽  
C. E. Pullin ◽  
J. O. Bromley ◽  
S. L. Macaulay
Keyword(s):  
Growth Hormone ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Human Growth Hormone ◽  
Mechanism Of Action ◽  
Human Growth
Sign in / Sign up

Export Citation Format

Share Document