Indications and Results of Prednisone Treatment in Thyroid Ophthalmopathy

1976 ◽  
Vol 173 (3-4) ◽  
pp. 163-167 ◽  
Author(s):  
R.C. Apers ◽  
J.A. Oosterhuis ◽  
J.J.M. Bierlaagh
2015 ◽  
pp. 163-167
Author(s):  
R. C. Apers ◽  
J. A. Oosterhuis ◽  
J. J. M. Bierlaagh

2015 ◽  
Vol 2 (3) ◽  
pp. 10-12
Author(s):  
Vimala Sheshadri Iyengar ◽  
Varun Gosain ◽  
Karnalli Jagannatha ◽  
Rampura Bommarayigowda Ramegowda

1994 ◽  
Vol 162 (3) ◽  
pp. 734-735 ◽  
Author(s):  
R A O'Neil ◽  
S L Ngu ◽  
I W Prosser

Author(s):  
Thaddeus S. Nowinski ◽  
Joseph C. Flanagan

1987 ◽  
Vol 72 (3) ◽  
pp. 329-334 ◽  
Author(s):  
Silvano Adami ◽  
G. Graziani ◽  
D. Tartarotti ◽  
R. Cappelli ◽  
S. Casati ◽  
...  

1. The response of circulating 1,25-dihydroxyvitamin D [l,25-(OH)2D] to challenge with vitamin D treatment both before and after 7–10 days of prednisone therapy (25 mg/day) was investigated in five anephric subjects, six patients with chronic renal failure (CRF), two patients with vitamin D intoxication and four patients with hypoparathyroidism. 2. In anephric subjects serum 25-hydroxyvitamin D [25-(OH)D] rose from 58 ± 48 (sd) to 377±221 (sd) nmol/l after administration of 150 μg of 25-(OH)D3 for 1 month. Serum l,25-(OH)2D, which was barely detectable in only two out of five patients under basal conditions, rose to 30 ± 21 pmol/l after 2 weeks of therapy with 25-(OH)D3, but fell to 10 ± 5 pmol/l during prednisone treatment. 3. In CRF patients circulating l,25-(OH)2D rose from 37 ± 24 to 58 ± 24 pmol/l during 25-(OH)D3 therapy, but fell to 41 ± 31 pmol/l during prednisone treatment. In two patients with rheumatoid arthritis, hypercalcaemia due to vitamin D intoxication was associated with raised levels of 1,25-(OH)2D (288 and 317 pmol/l). Administration of prednisore resulted in suppression of l,25-(OH)2D levels (132 and 96 pmol/l respectively) and reduction of serum calcium to within the normal range. 4. In the hypoparathyroid patients prednisone therapy did not affect circulating 25-(OH)D levels but serum l,25-(OH)2D fell from 192 ± 42 to 117 ± 23 pmol/l and serum calcium from 2.41 ± 0.21 to 2.20 ± 0.05 mmol/l. 5. These findings indicate that a steroid sensitive extrarenal production of l,25-(OH)2D may occur in all subjects with a threshold serum concentration of the precursor 25-(OH)D.


Diabetes Care ◽  
1987 ◽  
Vol 10 (1) ◽  
pp. 39-43 ◽  
Author(s):  
L. Mistura ◽  
L. Beccaria ◽  
F. Meschi ◽  
A. F. D'arcais, ◽  
C. Pellini ◽  
...  

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