Regional Variations in Uterine Blood Flow in the Guinea Pig: Relationship to Pregnancy Site Distribution

1983 ◽  
Vol 15 (1) ◽  
pp. 33-40 ◽  
Author(s):  
David R. Garris ◽  
Lamar T. Blankenship ◽  
D.S. Whitehead
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Uterine Blood Flow ◽  
Regional Variations ◽  
Site Distribution

Uterine blood flow and timing of blastocyst implantation in the guinea pig

1981 ◽  
Vol 241 (2) ◽  
pp. E142-E145
Author(s):  
D. R. Garris ◽  
D. S. Whitehead
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Guinea Pigs ◽  
Temporal Relationship ◽  
Oxygen Electrode ◽  
Uterine Blood Flow ◽  
Serum Estradiol ◽  
Dramatic Rise ◽  
Blastocyst Implantation

The temporal and direct relationships between serum estradiol (E) and progesterone (P) levels and uterine blood flow (UBF) and intrauterine oxygen tension (IU PO2) were examined in guinea pigs between days 1 and 8 of pregnancy. Both UBF and IU PO2 were measured in situ using a noninvasive electromagnetic blood flow monitor and needle oxygen electrode, respectively. Serum P levels remained relatively constant throughout the first 8 days of pregnancy. In contrast, serum E levels declined to basal levels between days 1 and 3, and then subsequently rose between days 4 and 7 before again falling to basal levels by day 8. The changes in UBF and IU PO2 paralleled those of serum E levels, both exhibiting a rise between days 5 and 6. The direct effect of oil, E, or P injections on UBF and IU PO2 measurements in ovariectomized animals indicated that E induced a dramatic rise in both uterine parameters, whereas both measurements remained at basal levels after oil or P treatment. The results of this study indicate that UBF and IU PO2 levels are directly regulated by the cyclic fluctuations in serum E. The temporal relationship between the days 4 to 7 rise in serum E, UBF, and IU PO2 levels and the timing of blastocyst implantation suggest that these events are involved in uterine preparation for nidation in the guinea pig.

scholarly journals Pregnancy Stimulation of DNA Synthesis and Uterine Blood Flow in the Guinea Pig

1997 ◽  
Vol 41 (5) ◽  
pp. 708-715 ◽  
Author(s):  
Linda E Keyes ◽  
Richard Majack ◽  
Edward C Dempsey ◽  
Lorna G Moore
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Dna Synthesis ◽  
Uterine Blood Flow ◽  
Stimulation Of

EFFECT OF INTRAVENOUS EPINEPHRINE UPON UTERINE BLOOD FLOW VELOCITY IN THE PREGNANT GUINEA PIG

1985 ◽  
Vol 63 (Supplement) ◽  
pp. A453
Author(s):  
D. H. Chestnut ◽  
C. P. Weiner ◽  
J. E. Herrig ◽  
J. Wang
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Uterine Blood Flow

CSE Tied to Brief Drop In Uterine Blood Flow

Ob Gyn News ◽  
2007 ◽  
Vol 42 (13) ◽  
pp. 23
Author(s):  
Kate Johnson
Keyword(s):  
Blood Flow ◽  
Uterine Blood Flow

Behavioral activity during prolonged hypoxemia in fetal sheep

1988 ◽  
Vol 65 (6) ◽  
pp. 2420-2426 ◽  
Author(s):  
A. D. Bocking ◽  
R. Gagnon ◽  
K. M. Milne ◽  
S. E. White
Keyword(s):  
Blood Flow ◽  
Eye Movements ◽  
Normal Incidence ◽  
Behavioral Activity ◽  
Uterine Blood Flow ◽  
Fetal Sheep ◽  
Pregnant Sheep ◽  
Fetal Breathing ◽  
Fetal Breathing Movements ◽  
Internal Iliac

Experiments were conducted in unanesthetized, chronically catheterized pregnant sheep to determine the fetal behavioral response to prolonged hypoxemia produced by restricting uterine blood flow. Uterine blood flow was reduced by adjusting a vascular occluder placed around the maternal common internal iliac artery to decrease fetal arterial O2 content from 6.1 +/- 0.3 to 4.1 +/- 0.3 ml/dl for 48 h. Associated with the decrease in fetal O2 content, there was a slight increase in fetal arterial PCO2 and decrease in pH, which were both transient. There was an initial inhibition of both fetal breathing movements and eye movements but no change in the pattern of electrocortical activity. After this initial inhibition there was a return to normal incidence of both fetal breathing movements and eye movements by 16 h of the prolonged hypoxemia. These studies indicate that the chronically catheterized sheep fetus is able to adapt behaviorally to a prolonged decrease in arterial O2 content secondary to the restriction of uterine blood flow.

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