Glycosylated Hemoglobins in Pregnant Women with Normal and Abnormal Glucose Tolerance

1994 ◽  
Vol 37 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Diana F.M. Loke ◽  
S. Chua ◽  
L.P. Kek ◽  
A.C. Thai ◽  
S.S. Ratnam
Keyword(s):  
Glucose Tolerance ◽  
Pregnant Women ◽  
Abnormal Glucose Tolerance

scholarly journals Prevalence of Abnormal Glucose Tolerance in Obese Pregnant Women - A Study from a Tertiary Care Centre

2021 ◽  
Vol 10 (44) ◽  
pp. 3769-3774
Author(s):  
Ann Mary George ◽  
Ajay Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Pregnant Women ◽  
Oral Glucose ◽  
Government Medical College ◽  
Abnormal Glucose Tolerance ◽  
Family History Of Diabetes ◽  
Medical College ◽  
History Of

BACKGROUND Obesity has emerged as an important risk factor in modern obstetrics and poses a major threat to pregnancy by causing complications including gestational diabetes. It also increases the risk of cardiovascular diseases and diabetes mellitus in later life. Obesity creates major technical challenges in providing maternity services too. The objective of the study was to assess the prevalence of abnormal glucose tolerance in obese pregnant women in a Government Medical College over one year. METHODS A prospective observational study was conducted among obese pregnant women, registered at the Outpatient department of Obstetrics and Gynaecology at the Government Medical College, Kottayam from January 2017 to December 2017. 450 women were considered for the study after satisfying inclusion and exclusion criteria. BMI was calculated using pre-pregnant weight. An oral glucose test was performed with 75 gm glucose at 24 to 28 weeks of pregnancy after 8 hours of fasting. International Association of Diabetes and Pregnancy Study Group cut-offs i.e., fasting blood sugar values more than 92 mg/dl, 1hr value more than 180 mg/dl, 2 hr value more than 153 mg/dl were used as the criteria. Oral glucose tolerance was considered abnormal if any of the above values were impaired. RESULTS The prevalence of abnormal glucose tolerance among the 450 pregnant women was 35.6 %. The incidence of abnormal GTT increased with increasing age and in those with a history of menstrual irregularities and infertility treatment. No relation was found between economic status, family history of diabetes, preeclampsia and abnormal GTT. CONCLUSIONS Obesity turns to be a menace in the reproductive life of women that begins by affecting the fertility, continues to cause complications in pregnancy, increases morbidity in the long-term future and reduces the quality of life. Since more than one-third of the study population was affected by gestational diabetes, active intervention to reduce the weight preconceptionally is needed. KEY WORDS Obesity, Glucose Tolerance Test, Gestational Diabetes Mellitus, Body Mass Index, Pregnancy

scholarly journals Cardiac Diastolic Evaluation in Pregnant Women with Abnormal Glucose Tolerance: An Opportunity to Detect the Early and Subclinical Alterations and Prevent Cardiovascular Diseases

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
B. Pintaudi ◽  
G. Di Vieste ◽  
F. Corrado ◽  
M. F. Creazzo ◽  
A. Fazio ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Cardiovascular Diseases ◽  
Glucose Tolerance ◽  
Pregnant Women ◽  
Diastolic Function ◽  
Wave Velocity ◽  
Model Assessment ◽  
Abnormal Glucose Tolerance ◽  
Diastolic Velocity ◽  
Increased Risk

Objectives of this study were to assess diastolic function in pregnant women with abnormal glucose tolerance (AGT), compared with normal glucose tolerance (NGT) women, and to evaluate the insulin resistance status and its association with Doppler-echocardiographic indexes. Echocardiograms of 108 consecutive Caucasian women with singleton pregnancies were performed. Insulin resistance status was estimated by the homeostasis model assessment of insulin resistance (HOMA-IR) and the quantitative insulin sensitivity check index (QUICKI). All the studied women showed normal diastolic patterns. Patients with AGT (50.9%), as compared with NGT women, had higher HOMA-IR (1.70±1.30versus1.01±0.81,P=0.003), lower QUICKI (0.36±0.005versus0.40±0.06,P=0.004), higher lateral mitral annulus late diastolic velocity (13.6±4.9versus11.9±4.9,P=0.03), and higher A-wave velocity, the wave responsible for the active atrial contraction component (75.2±14.2versus67.7±16.2,P=0.01). At multivariate regression analysis HOMA-IR was the only parameter associated with A-wave velocity. In conclusion, women with AGT had an increased subclinical diastolic active participation, which is associated with higher levels of insulin resistance. For the increased risk of deterioration of cardiac diastolic function, earlier and more seriously than normal pregnancy, AGT women may have a careful followup to detect the early signs of cardiac alteration and to prevent cardiovascular diseases.

scholarly journals Continuous Glucose Monitoring in Patients with Abnormal Glucose Tolerance during Pregnancy: A Case Series

2016 ◽  
Vol 7 ◽  
pp. JCM.S34825 ◽  
Author(s):  
Mie Tonoike ◽  
Miyako Kishimoto ◽  
Mayumi Yamamoto ◽  
Tetsu Yano ◽  
Mitsuhiko Noda
Keyword(s):  
Glycemic Control ◽  
Glucose Tolerance ◽  
Pregnant Women ◽  
Glucose Intolerance ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Case Series ◽  
Postprandial Hyperglycemia ◽  
Abnormal Glucose Tolerance ◽  
Glucose Fluctuations

Abnormal glucose tolerance during pregnancy is associated with perinatal complications. We used continuous glucose monitoring (CGM) in pregnant women with glucose intolerance to achieve better glycemic control and to evaluate the maternal glucose fluctuations. We also used CGM in women without glucose intolerance (the control cases). Furthermore, the standard deviation (SD) and mean amplitude of glycemic excursions (MAGE) were calculated for each case. For the control cases, the glucose levels were tightly controlled within a very narrow range; however, the SD and MAGE values in pregnant women with glucose intolerance were relativity high, suggesting postprandial hyperglycemia. Our results demonstrate that pregnant women with glucose intolerance exhibited greater glucose fluctuations compared with the control cases. The use of CGM may help to improve our understanding of glycemic patterns and may have beneficial effects on perinatal glycemic control, such as the detection of postprandial hyperglycemia in pregnant women.

scholarly journals Plasma zinc and magnesium concentrations in pregnant women with abnormal glucose tolerance

2006 ◽  
Vol 20 (5) ◽  
Author(s):  
Jessica De Haene ◽  
Tuan Nguyen ◽  
Ratna Mukherjea ◽  
Luz Maria De Regil ◽  
Janet C King ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Pregnant Women ◽  
Plasma Zinc ◽  
Abnormal Glucose Tolerance

Effect of interventions in pregnant women with mildly impaired glucose tolerance

2021 ◽  
Author(s):  
Ryosuke Shindo ◽  
Shigeru Aoki ◽  
Junko Kasai ◽  
Sayuri Nakanishi ◽  
Yusuke Saigusa ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Pregnant Women ◽  
Impaired Glucose Tolerance
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