Relation between Basement Membrane Degradation and Serum Levels of Laminin P1 in Patients with Transitional Cell Carcinoma of the Bladder

1993 ◽  
Vol 50 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Abou Farha ◽  
P.P.C.A. Menheere ◽  
F.H.M. Nieman ◽  
R.A. Janknegt ◽  
J.W. Arends
Keyword(s):  
Basement Membrane ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Serum Levels ◽  
Membrane Degradation ◽  
Carcinoma Of The Bladder ◽  
Basement Membrane Degradation

Squamous cell carcinoma antigen in genitourinary tumors

1989 ◽  
Vol 4 (4) ◽  
pp. 226-228 ◽  
Author(s):  
K.I. Wishnow ◽  
D.E. Johnson ◽  
H.A. Fritsche
Keyword(s):  
Squamous Cell Carcinoma ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Germ Cell Tumors ◽  
Serum Levels ◽  
Metastatic Adenocarcinoma ◽  
Adenocarcinoma Of The Prostate ◽  
Carcinoma Of The Bladder ◽  
Scc Antigen

We have evaluated the serum levels of squamous cell carcinoma (SCC) antigen in patients with adenocarcinoma of the kidney, adenocarcinoma of the prostate, germ cell tumors of the testis, transitional cell carcinoma of the bladder, and SCC of the penis, urethra, and bladder. Serum SCC antigen levels were elevated in 5 of 11 patients (45%) with metastatic SCC of the penis, and in the 3 patients for whom serial determinations were made, the serum levels correlated correctly with the progression of disease or response to treatment. The antigen was elevated in 1 of 3 patients with SCC of the urethra, and 1 apparent false-positive value was observed in a patient with adenocarcinoma of the prostate. Otherwise, no SCC antigen elevations were noted among 10 patients with metastatic adenocarcinoma of the prostate, 8 with metastatic adenocarcinoma of the kidney, 11 with metastatic transitional cell carcinoma of the bladder, 8 with metastatic nonseminomatous germ cell tumors of the testis, and 2 patients with metastatic SCC of the bladder

969: Intravesical Antisense G3139 Efficacy in Transitional Cell Carcinoma of the Bladder

2004 ◽  
Vol 171 (4S) ◽  
pp. 257-257
Author(s):  
Sam B. Gray ◽  
Brian J. Duggan ◽  
Perry Maxwell ◽  
Ken Arthur ◽  
Neil Anderson ◽  
...  
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Carcinoma Of The Bladder

scholarly journals A Rare Case of Sensory Neuropathy Associated with Transitional Cell Carcinoma of the Bladder

2020 ◽  
Vol 13 (3) ◽  
pp. 1397-1401
Author(s):  
Sujitha Ketineni ◽  
Sreenath Kodali ◽  
Sasikanth Gorantla
Keyword(s):  
Lymph Nodes ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Rare Case ◽  
Transitional Cell ◽  
Sensory Neuropathy ◽  
Endobronchial Ultrasound ◽  
Whole Body ◽  
Initial Symptoms ◽  
Carcinoma Of The Bladder

Malignancies can trigger an autoimmune response against the nervous system and manifest as paraneoplastic neurological syndromes (PNS). Initial symptoms of PNS may develop up to 5 years prior to the diagnosis of the underlying malignancy. We report a rare case of PNS associated with transitional cell carcinoma of the bladder in a 70-year-old male with a 6-month history of rapidly progressive symmetric sensory neuropathy. Peripheral neuropathy serological workup was unremarkable. A paraneoplastic neuropathy panel revealed anti-Hu autoantibodies. Further evaluation with a whole-body PET scan could not identify the primary malignancy, but it showed hypermetabolic hilar lymph nodes. An endobronchial ultrasound biopsy of the hilar lymph nodes was negative for cancer. The patient developed painless hematuria 2.5 years after the onset of the sensory neuropathy. Cystoscopy with biopsy revealed non-muscle-invasive transitional cell carcinoma of the bladder. Progression of the sensory neuropathy stopped after tumor resection. This case highlights the importance of a diligent and systematic approach to diagnose PNS. A relentless search is often required to detect PNS-associated occult malignancies.

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