Primary Malignant Melanoma of the Female Urethra: A Case Report with Immunohistochemical Findings

1988 ◽  
Vol 43 (2) ◽  
pp. 110-112 ◽  
Author(s):  
G. Barbagli ◽  
A. Natali ◽  
C. Urso ◽  
G. Barbanti ◽  
I. Menchi ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Primary Malignant Melanoma ◽  
Female Urethra

scholarly journals PRIMARY MALIGNANT MELANOMA OF THE FEMALE URETHRA: A CASE REPORT

2018 ◽  
Vol 109 (2) ◽  
pp. 111-115 ◽  
Author(s):  
Hiroaki Suzuki ◽  
Yasukazu Nakanishi ◽  
Koji Yoshino ◽  
Madoka Kataoka ◽  
Hiroshi Fukushima ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Primary Malignant Melanoma ◽  
Female Urethra

S298: Primary malignant melanoma of female urethra: Case report

2014 ◽  
Vol 13 (7) ◽  
pp. e1605
Author(s):  
K. Moysidis ◽  
P. Georgopoulos ◽  
K. Kazanas ◽  
I. Sokolakis ◽  
K. Ksouplidis ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Primary Malignant Melanoma ◽  
Female Urethra

scholarly journals Primary malignant melanoma of female urethra: a case report and review of literature

2020 ◽  
Vol 1 (3) ◽  
Author(s):  
Shashank Agrawal ◽  
Tak GR ◽  
Aditya Parikh ◽  
Arvind Prakash Ganpule ◽  
Abhishek Gajendra Singh ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Protein S ◽  
Primary Malignant Melanoma ◽  
Female Urethra ◽  
Inguinal Lymph Node Dissection ◽  
Rare Case Report ◽  
S 100 ◽  
History Of ◽  
Poorly Differentiated

We report an extremely rare case report of primary malignant melanoma of female urethra. A 65 years old diabetic elderly postmenopausal female presented with a history of intermittent blood spots on undergarments for few days. Genital examination revealed a single, tan colored, soft chestnut size and polypoidal non ulcerated mass lesion protruding through the urethral meatus. Mass biopsy revealed poorly differentiated epithelial malignancy and immuno-histological analysis revealed positive with HMB 45 and protein S-100 suggestive of melanoma. Metastatic work up for the malignancy was negative. Complete urethrectomy with Mitrofanoff procedure with inguinal lymph node dissection was performed. Pathological diagnosis was malignant melanoma of urethra. We discuss the clinicopathological features and treatment option possible in this scenario.

scholarly journals Primary malignant melanoma of the female urethra: A case report

2021 ◽  
Vol 34 ◽  
pp. 101493
Author(s):  
Kazuhiro Watanabe ◽  
Go Hasegawa ◽  
Katsunori Kashima ◽  
Yo Sato ◽  
Noboru Hara ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Primary Malignant Melanoma ◽  
Female Urethra

Primary malignant melanoma of the female urethra: A case report

1995 ◽  
Vol 27 (1) ◽  
pp. 107-111 ◽  
Author(s):  
F. Aragona ◽  
G. Maio ◽  
R. Piazza ◽  
R. Salmaso
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Primary Malignant Melanoma ◽  
Female Urethra

scholarly journals Primary malignant melanoma of the trachea: A case report

2014 ◽  
Vol 9 (2) ◽  
pp. 657-660 ◽  
Author(s):  
HISAO IMAI ◽  
YOSHIO KIYOHARA ◽  
SHUSUKE YOSHIKAWA ◽  
NAO KUSUTANI ◽  
AKIRA ONO ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Primary Malignant Melanoma

scholarly journals Carbon ion radiotherapy with complete tumor regression for primary malignant melanoma of female urethra orifice: a case report

2022 ◽  
Vol 50 (1) ◽  
pp. 030006052110727
Author(s):  
Xiaojun Li ◽  
Yihe Zhang ◽  
Yanshan Zhang ◽  
Yancheng Ye ◽  
Ying Qi ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Tumor Regression ◽  
Treatment Protocol ◽  
Carbon Ion Radiotherapy ◽  
Primary Malignant Melanoma ◽  
Radiation Dermatitis ◽  
Survival Duration ◽  
Female Urethra ◽  
Carbon Ion ◽  
Complete Tumor

Primary malignant melanoma of the female urethra (PMMFU) is extremely rare, accounting for 0.2% of all melanomas, and fewer than 200 cases have been reported worldwide. Because of the small number of clinical cases and unclear biological characteristics, there is no uniform and standard treatment protocol. We herein describe the treatment of PMMFU using carbon ion radiotherapy. The radiotherapy was delivered at 60.8 Gy (RBE) in 16 fractions, once daily, five times per week. The patient achieved complete tumor disappearance within 1 year after carbon ion radiotherapy and remained disease-free thereafter. She developed acute grade 1 radiation dermatitis and urethritis, which resolved quickly; no other toxic effects were observed. At the time of this writing, her survival duration was 33 months. This case demonstrates that carbon ion radiotherapy may be a good option for primary genitourinary mucosal malignancies.

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