Effects of Hyperventilation and Hypoventilation on Cochlear Blood Flow and Endocochlear Direct-Current Potential

ORL ◽  
1995 ◽  
Vol 57 (4) ◽  
pp. 171-176 ◽  
Author(s):  
Hirofumi Yamamoto ◽  
Kazuo Makimoto ◽  
Michiro Kawakami ◽  
Yoshimitsu Ohinata ◽  
Hiroaki Takahashi
2021 ◽  
Author(s):  
Friedrich Ihler ◽  
Saskia Freytag ◽  
Benedikt Kloos ◽  
Jennifer Lee Spiegel ◽  
Frank Haubner ◽  
...  

1993 ◽  
Vol 113 (2) ◽  
pp. 146-151 ◽  
Author(s):  
Tian-Ying Ren ◽  
E. Laurikainen ◽  
W. S. Quirk ◽  
J. M. Miller ◽  
A. L. Nuttall

2013 ◽  
Vol 77 (6) ◽  
pp. 981-985 ◽  
Author(s):  
Chul Ho Jang ◽  
Yong Beom Cho ◽  
Cheol Hee Choi ◽  
Jae-Young Um ◽  
Pa-Chun Wang ◽  
...  

1987 ◽  
Vol 104 (3-4) ◽  
pp. 243-250 ◽  
Author(s):  
Maria Hillerdal ◽  
Erik Borg ◽  
Berit Engstrom ◽  
Elisabeth Hultcrantz

1990 ◽  
Vol 10 (3) ◽  
pp. 358-364 ◽  
Author(s):  
F. Tegtmeier ◽  
C. Weber ◽  
U. Heister ◽  
I. Haker ◽  
D. Scheller ◽  
...  

The effects of complete ischemia on cerebral arachidonic acid (AA) metabolism were investigated in the isolated perfused rat brain. During 12.5 min of ischemia, AA, 5-hydroxy-6,8,11,14-eicosatetraenoic acid, and 15-hydroxy-5,8,11,13-eicosatetraenoic acid increased 129-, 4-, and 10-fold, respectively, while subsequent reperfusion for 30 min resulted in normalized levels independently of the duration of preceding ischemia. Prostaglandin (PG) F2α, PGE2, PGD2, 6-keto-PGF1α, and thromboxane (Tx) B2 remained at preischemic levels during 12.5 min of complete ischemia. However, at the end of subsequent reperfusion for 30 min, the levels of the prostanoids PGF2α, PGE2, PGD2, 6-keto-PGF1α, and TxB2 increased according to the preceding ischemic time. The levels reached a maximum after 7.5 min of ischemia and were elevated by 7-, 14-, 48-, 3-, and 30-fold, respectively. A prolongation of ischemia of up to 12.5 min was not associated with further increases of prostanoids at the end of reperfusion. The mechanisms underlying the metabolism of eicosanoids are discussed in relation to the changes of cortical direct current potential.


2001 ◽  
Vol 121 (2) ◽  
pp. 130-134 ◽  
Author(s):  
Hideki Takago, Kazunori Yokoyama, K

1989 ◽  
Vol 246 (3) ◽  
pp. 147-150 ◽  
Author(s):  
M. Kawakami ◽  
K. Makimoto ◽  
T. Nakajima ◽  
H. Takahashi

1987 ◽  
Vol 96 (4) ◽  
pp. 341-348 ◽  
Author(s):  
Daniel Zaluzec ◽  
Joseph Ramzy ◽  
Robert Wotring ◽  
Lincoln Gray

Chickens were injected with 9-micron-diameter radioactive microspheres. Cochleas were removed through the external auditory meatus, and the positions of all embedded microspheres were drawn under camera-lucida. Constant measurements of arterial pressures and postinjection blood-gas determinations confirmed that injections were made into normal circulatory systems. The averaged estimate of cochlear blood flow in chickens is 0.75 μl/min. Variability in these data from chickens is similar to that reported from mammals. A potentially important but puzzling observation is an inverse relationship between blood flow to the cochlea and to the brain. The ease of cochlear extraction makes chickens ideal models for study of cochlear blood flow.


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