Effects of Ischemia-Reperfusion on Light-Evoked Alkalinization Outside Rod Photoreceptors in the Cat Retina

1993 ◽  
Vol 25 (6) ◽  
pp. 371-377
Author(s):  
Fumiaki Yamamoto ◽  
Kano Hiroi ◽  
Yoshihito Honda
Author(s):  
Michael A. Freed ◽  
Peter Sterling

One of the most basic of structure-function relationships in the mammalian visual system is the relationship between the size of a ganglion cell's receptive field and the number of rod photoreceptors which are connected to it. There is also the flip side of the coin: how many ganglion cells does a single photoreceptor connect to? We have estimated the number of rods which converge upon an on-beta type of retinal ganglion cell; we have also estimated the number of on-beta ganglion cells which a single rod diverges to. Our method is to extract a three-dimensional circuit from a series of two-dimensional electron microscope sections. The results have implications for the preservation of the signal/noise ratio in the ganglion cell.There are two well-documented routes from the rods to the on-beta ganglion cell.


1992 ◽  
Vol 54 (5) ◽  
pp. 685-697 ◽  
Author(s):  
Fumiaki Yamamoto ◽  
Gerard A. Borgula ◽  
Roy H. Steinberg

Author(s):  
Peter Sterling

The synaptic connections in cat retina that link photoreceptors to ganglion cells have been analyzed quantitatively. Our approach has been to prepare serial, ultrathin sections and photograph en montage at low magnification (˜2000X) in the electron microscope. Six series, 100-300 sections long, have been prepared over the last decade. They derive from different cats but always from the same region of retina, about one degree from the center of the visual axis. The material has been analyzed by reconstructing adjacent neurons in each array and then identifying systematically the synaptic connections between arrays. Most reconstructions were done manually by tracing the outlines of processes in successive sections onto acetate sheets aligned on a cartoonist's jig. The tracings were then digitized, stacked by computer, and printed with the hidden lines removed. The results have provided rather than the usual one-dimensional account of pathways, a three-dimensional account of circuits. From this has emerged insight into the functional architecture.


2001 ◽  
Vol 120 (5) ◽  
pp. A379-A379
Author(s):  
Y TAKAMATSU ◽  
K SHIMADA ◽  
K CHIJIWA ◽  
M TANAKA

2006 ◽  
Vol 175 (4S) ◽  
pp. 521-521
Author(s):  
Motoaki Saito ◽  
Tomoharu Kono ◽  
Yukako Kinoshita ◽  
Itaru Satoh ◽  
Keisuke Satoh

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