Modulation of Experimental Phacoanaphylactic Endophthalmitis with the Antioxidants Sodium Benzoate, and 2,3-Dihydroxybenzoic Acid

1987 ◽  
Vol 19 (2) ◽  
pp. 120-128 ◽  
Author(s):  
George E. Marak, Jr. ◽  
Narsing A. Rao ◽  
Alex Sevanian ◽  
Vera Zdravkovich ◽  
Gerd O. Till ◽  
...  
Keyword(s):  
Sodium Benzoate ◽  
Dihydroxybenzoic Acid

The preparation of 3-amino-3-deoxy-1,2-O-isopropylidene-α-L-erythrofuranose, 3-amino-3-deoxy-1,2-O-isopropylidene-β-D-threofuranose and their derivatives

1980 ◽  
Vol 45 (12) ◽  
pp. 3378-3390 ◽  
Author(s):  
Jiří Jarý ◽  
Milena Masojídková ◽  
Ivan Kozák ◽  
Miroslav Marek ◽  
Jan Staněk
Keyword(s):  
Nucleophilic Substitution ◽  
Sodium Azide ◽  
Sodium Benzoate ◽  
Nmr Spectra ◽  
Subsequent Reduction ◽  
H Nmr ◽  
Amino Derivatives

The title amino derivatives VI and XIV were prepared by nucleophilic substitution of p-toluenesulfonyl derivatives II and XVII with sodium azide or hydrazine and subsequent reduction. Nucleophilic substitution of compounds II and XVII with sodium benzoate was also investigated. The 1H NMR spectra of the substances prepared are discussed.

scholarly journals Gross morphology of thymus and spleen in rats after formation of defect in the tibia and sodium benzoate intake

Bone Reports ◽  
2021 ◽  
Vol 14 ◽  
pp. 100889
Author(s):  
Vladyslav Luzin ◽  
Irina Belik ◽  
Dmitry Astrakhantsev ◽  
Nadezhda Mosyagina
Keyword(s):  
Sodium Benzoate

scholarly journals EFFECT OF COCAINE ON THE GROWTH OF LUPINUS ALBUS. A CONTRIBUTION TO THE COMPARATIVE PHARMACOLOGY OF ANIMAL AND PLANT PROTOPLASM

1922 ◽  
Vol 4 (5) ◽  
pp. 573-584 ◽  
Author(s):  
David I. Macht ◽  
Marguerite B. Livingston
Keyword(s):  
Sodium Benzoate ◽  
Lupinus Albus ◽  
The Other ◽  
Plant Roots ◽  
Animal Tissues ◽  
Decomposition Products ◽  
Other Hand ◽  
Low Toxicity

1. The effects of cocaine and its decomposition products were studied on the growth of the young roots of Lupinus albus. 2. The results obtained were compared with similar experiments on animal tissues. 3. It was found that, while cocaine is the most toxic of these compounds studied for animal tissues, it was of comparatively low toxicity in respect to its effect on the growth of roots. On the other hand, sodium benzoate, being practically non-toxic for animals, was the most toxic of the compounds studied for the plant roots.

scholarly journals The effect of chelating agents on iron mobilization in Chang cell cultures

Blood ◽  
1976 ◽  
Vol 48 (6) ◽  
pp. 923-929 ◽  
Author(s):  
GP White ◽  
A Jacobs ◽  
RW Grady ◽  
A Cerami
Keyword(s):  
Cell Cultures ◽  
Chelating Agents ◽  
Transferrin Saturation ◽  
Molar Ratio ◽  
Iron Release ◽  
Dihydroxybenzoic Acid ◽  
Equal Degree ◽  
Therapeutic Value ◽  
Chang Cell

Abstract The investigation of chelating agents with potential therapeutic value in patients with transfusional iron overload has been facilitated by the use of Chang cell cultures. These cells have been incubated with [59Fe]transferrin for 22 hr, following which most of the intracellular radioiron is found in the cytosol, distributed between a ferritin and a nonferritin form. Iron release from the cells depends on transferrin saturation in the medium, but when transferrin is 100% saturated, which normally does not allow iron release, desferrioxamine, 2,3- dihydroxybenzoic acid, rhodotorulic acid, cholythydroxamic acid, and tropolone all promote the mobilization of ferritin iron and its release from cells. They are effective to an approximately equal degree. The incubation of [59Fe]transferrin with tropolone in vitro at a molar ratio of 1:500 results in the transfer of most of the labeled iron to the chelator, reflecting the exceptionally high binding constant of this compound. How far these phenomena relate to therapeutic potentially remains to be seen.

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