Radiation Cataractogenesis in the Amphibian Lens

1982 ◽  
Vol 14 (2) ◽  
pp. 73-82 ◽  
Author(s):  
B.V. Worgul ◽  
H. Rothstein ◽  
C. Medvedovsky ◽  
G.R. Merriam, Jr. ◽  
M.A Wilson
Keyword(s):  
Amphibian Lens

The zinc metabolism of the amphibian lens

1980 ◽  
Vol 30 (4) ◽  
pp. 333-343 ◽  
Author(s):  
Geraldine F. Baldwin ◽  
P.J. Bentley
Keyword(s):  
Zinc Metabolism ◽  
Amphibian Lens

scholarly journals Amphibian Lens Histones and Their Relation to the Cell Cycle

1970 ◽  
Vol 55 (5) ◽  
pp. 688-702 ◽  
Author(s):  
Alan Johnson ◽  
Howard Rothstein
Keyword(s):  
Cell Cycle ◽  
Epithelial Cells ◽  
Dna Synthesis ◽  
Tissue Specific ◽  
Fiber Cells ◽  
Early Stages ◽  
Histone Synthesis ◽  
Inhibition Of Dna Synthesis ◽  
First Time ◽  
Amphibian Lens

Histones have been electrophoretically separated from acid extracts of the frog lens for the first time. The five conventional histone fractions, representing four electrophoretic bands (f1; f2b, f3; f2a2; and f2a1), are present in both the epithelial and fiber cells. In addition, a fifth fraction was isolated from both sources and the evidence suggests that it may be a tissue-specific histone, possibly related to the lysine-rich f2c fraction found previously only in nucleated erythrocytes. The epithelial cells contain a substantially greater amount of histone than the fiber cells. Moreover, the fibers, unlike the epithelium, manifest no net histone synthesis or turnover following lenticular explantation. Microspectrophotometric, radioautographic, and gel electrophoretic studies indicate that the histones are synthesized in frog lenses concurrently with DNA. Inhibition of DNA synthesis does not completely abolish that of histones but reduces it by about one-half. In the early stages of culture (prior to their synthesis and that of DNA) the histones appear to undergo alterations which are prevented by treatment with cycloheximide.

The calcium metabolism of the amphibian lens

1980 ◽  
Vol 30 (4) ◽  
pp. 379-389 ◽  
Author(s):  
Geraldine F. Baldwin ◽  
P.J. Bentley
Keyword(s):  
Calcium Metabolism ◽  
Amphibian Lens

Synthesis of macromolecules in epithelial cells of the cultured amphibian lens

1968 ◽  
Vol 50 (2) ◽  
pp. 454-459 ◽  
Author(s):  
M. Bagchi ◽  
H. Rothstein ◽  
G.S. Stein
Keyword(s):  
Epithelial Cells ◽  
Amphibian Lens
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