Forward Masking Is Dependent on Inner Hair Cell Activity

1996 ◽  
Vol 1 (6) ◽  
pp. 320-327 ◽  
Author(s):  
Mao Li Duan ◽  
Barbara Canlon
Keyword(s):  
Hair Cell ◽  
Cell Activity ◽  
Forward Masking ◽  
Inner Hair Cell

Effects of inner hair cell loss on inferior colliculus evoked potential thresholds, amplitudes and forward masking functions in chinchillas

1998 ◽  
Vol 120 (1-2) ◽  
pp. 121-132 ◽  
Author(s):  
Sandra L McFadden ◽  
Craig Kasper ◽  
Judith Ostrowski ◽  
Dalian Ding ◽  
Richard J Salvi
Keyword(s):  
Hair Cell ◽  
Inferior Colliculus ◽  
Evoked Potential ◽  
Cell Loss ◽  
Forward Masking ◽  
Hair Cell Loss ◽  
Inner Hair Cell

Dopamine regulates the glutamatergic inner hair cell activity in guinea pigs

1997 ◽  
Vol 107 (1-2) ◽  
pp. 46-52 ◽  
Author(s):  
Elmar Oestreicher ◽  
Wolfgang Arnold ◽  
Klaus Ehrenberger ◽  
Dominik Felix
Keyword(s):  
Hair Cell ◽  
Guinea Pigs ◽  
Cell Activity ◽  
Inner Hair Cell

scholarly journals Inner hair cell stereocilia are embedded in the tectorial membrane

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Pierre Hakizimana ◽  
Anders Fridberger
Keyword(s):  
Electron Microscopy ◽  
Hair Cell ◽  
Mechanical Stimulation ◽  
Hair Cells ◽  
Viscous Drag ◽  
Tectorial Membrane ◽  
Inner Hair Cell ◽  
Inner Hair Cells ◽  
Inward Currents

AbstractMammalian hearing depends on sound-evoked displacements of the stereocilia of inner hair cells (IHCs), which cause the endogenous mechanoelectrical transducer channels to conduct inward currents of cations including Ca2+. Due to their presumed lack of contacts with the overlaying tectorial membrane (TM), the putative stimulation mechanism for these stereocilia is by means of the viscous drag of the surrounding endolymph. However, despite numerous efforts to characterize the TM by electron microscopy and other techniques, the exact IHC stereocilia-TM relationship remains elusive. Here we show that Ca2+-rich filamentous structures, that we call Ca2+ ducts, connect the TM to the IHC stereocilia to enable mechanical stimulation by the TM while also ensuring the stereocilia access to TM Ca2+. Our results call for a reassessment of the stimulation mechanism for the IHC stereocilia and the TM role in hearing.

Free radical scavenger protects against inner hair cell loss after cochlear ischemia

Neuroreport ◽  
2003 ◽  
Vol 14 (14) ◽  
pp. 1881-1884 ◽  
Author(s):  
Toshiki Maetani ◽  
Nobuhiro Hakuba ◽  
Masafumi Taniguchi ◽  
Jun Hyodo ◽  
Yoshitaka Shimizu ◽  
...  
Keyword(s):  
Free Radical ◽  
Hair Cell ◽  
Cell Loss ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Hair Cell Loss ◽  
Inner Hair Cell

scholarly journals A Complex of RIM2alpha and RIM-Binding Protein 2 Stabilizes Slow Voltage-Dependent Inactivation of Cochlear Inner Hair Cell Cav1.3 L-Type Ca2+ Channels

2018 ◽  
Vol 114 (3) ◽  
pp. 637a-638a
Author(s):  
Nadine J. Ortner ◽  
Alexandra Pinggera ◽  
Anita Siller ◽  
Nadja Hofer ◽  
Niels Brandt ◽  
...  
Keyword(s):  
Hair Cell ◽  
Binding Protein ◽  
Inner Hair Cell ◽  
Dependent Inactivation ◽  
Voltage Dependent ◽  
Ca2 Channels
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